2-Buthyl-1-H-imidazole-4(5)-carbaldehyde

2-Butyl-1-H-imidazole-4 (5) -formaldehyde is an organic compound. It has unique chemical properties. In terms of physical properties, under normal conditions, or as a solid, due to the molecular structure containing a variety of groups, its melting point and boiling point are affected by the interaction of groups. The molecule contains a long carbon chain of butyl, which enhances the dispersion force between molecules, or increases the melting point and boiling point. At the same time, the existence of imidazole ring and aldehyde group makes the molecule have a certain polarity and may have certain solubility in polar solvents such as ethanol and acetone.
In terms of chemical properties, aldehyde groups are active and can undergo many reactions. First, oxidation reaction can occur. In case of common oxidants such as Torun reagent and Feilin reagent, aldehyde group can be easily oxidized to carboxyl group to obtain 2-butyl-1-H-imidazole-4 (5) -carboxylic acid. Second, reduction reaction can occur. Under the action of reducing agents such as lithium aluminum hydride and sodium borohydride, aldehyde group can be reduced to alcohol hydroxyl group to generate 2-butyl-1-H-imidazole-4 (5) -methanol. Furthermore, aldehyde group can undergo nucleophilic addition reaction with compounds containing active hydrogen. If it reacts with alcohol, acetal can be formed; if it reacts with amine, imine can be formed.
In addition, the imidazole ring also has certain reactivity. The nitrogen atom on the ring has a lone pair electron, which can participate in the reaction as an electron donor. For example, it can undergo nucleophilic substitution reaction with halogenated hydrocarbons, introducing new substituents on the imidazole ring nitrogen atom. At the same time, the conjugate system of the imidazole ring makes the whole molecule relatively stable, which also affects the aldehyde reactivity, making the reaction selective and unique.

The common synthesis methods of 2-butyl-1-H-imidazole-4 (5) -formaldehyde are as follows.
First, it can be alkylated and formylated by imidazole derivatives. First, the alkylation reaction is carried out with a suitable imidazole compound and halobutane in a suitable solvent in the presence of a base. Bases such as potassium carbonate, sodium hydride, etc., the solvent can be N, N-dimethylformamide (DMF), acetonitrile, etc. After the alkylation reaction is completed, the product is then formylated. The common reagent for formylation is the combination of N, N-dimethylformamide (DMF) and phosphorus oxychloride (POCl). The target product can be obtained by reaction at low temperature and then hydrolysis treatment.
Second, it can also be obtained by cyclization from raw materials containing specific substituents. For example, a compound containing butyl and a functional group that can be cyclized to form an imidazole ring is used as a starting material and cyclized under suitable catalyst and reaction conditions. The catalyst may be an acidic catalyst such as p-toluenesulfonic acid. The reaction conditions need to consider factors such as temperature and time to cyclize the molecule, and at the same time construct an imidazole ring and a formyl group, and finally obtain 2-butyl-1-H-imidazole-4 (5) -formaldehyde.
Furthermore, the tandem strategy of multi-step reaction is also feasible. The structure of imidazole ring was constructed gradually, and then butyl group and formyl group were introduced in turn. The reaction conditions needed to be precisely controlled in each step to achieve higher yield and selectivity, so as to successfully synthesize the target 2-butyl-1-H-imidazole-4 (5) -formaldehyde.

2-Butyl-1-H-imidazole-4 (5) -formaldehyde is useful in many fields.
In the field of pharmaceutical research and development, it may be a key intermediate. Due to the diverse biological activities of imidazole compounds, based on this substance, new drugs can be chemically modified, such as antibacterial and antiviral agents. Due to its unique structure, it can fit with specific targets in organisms, and then regulate physiological processes to achieve the effect of treating diseases.
In the field of materials science, it also has extraordinary performance. It can be used to prepare functional materials, such as materials with special optical and electrical properties. By reacting with other compounds through its aldehyde group, complex structures are constructed, giving novel properties to materials, which are applied to optoelectronic devices, sensors, etc., so that device performance can be improved.
In the field of organic synthesis, it is an important building block. With its active groups in its structure, it participates in a variety of organic reactions, such as condensation reactions, addition reactions, etc., assisting in the synthesis of complex organic molecules, enriching the types of organic compounds, and contributing to the development of organic synthesis chemistry.
In addition, in the field of catalysis, it can be used as a ligand to combine with metal ions to form catalysts, which play a catalytic role in specific chemical reactions, improve reaction efficiency and selectivity, and reduce the requirements of reaction conditions. It has potential application value in chemical production and other processes.

The question you are asking is about the market price of 2-butyl-1-H-imidazole-4 (5) -formaldehyde. However, the market price of this chemical often changes for many reasons, and it is difficult to generalize.
First, the price of raw materials has a great impact. If the price of the raw materials required for the preparation of this aldehyde fluctuates, the cost of this aldehyde will also change, and the market price will eventually fluctuate. Second, the preparation method is also the key. An efficient and low-cost preparation process can reduce its production cost, and the market price is also different.
Furthermore, the supply and demand relationship in the market determines the price. If there are many people who need this product, but the output is limited, the price will rise; conversely, if the supply is abundant and the demand is weak, the price may fall. And different regions, due to differences in transportation costs, market competition, etc., the price also varies.
To know the exact market price of this 2-butyl-1-H-imidazole-4 (5) -formaldehyde, it is advisable to consult the chemical raw material supplier, or check the chemical product trading platform, in order to obtain recent and accurate price information. The market is ever-changing, and the real-time price is not constant for a long time. The current inquiry shall prevail.

2-Butyl-1-H-imidazole-4 (5) -formaldehyde, this is a rather special chemical substance. Its storage conditions are extremely critical, related to its stability and quality.
The cover is very easy to interact with the surrounding environmental factors due to its active chemical properties. First, it should be placed in a cool place. Extreme heat will accelerate its chemical reaction process and cause it to deteriorate. Although "Tiangong Kaiwu" does not directly mention this chemical substance, it also has the same reason for the collection and storage of objects. If the hiding place should be protected from the sun heat, this chemical substance should also be kept away from high-temperature heat sources, and the temperature should not exceed 25 ° C.
Secondly, keep it dry. Moisture can easily cause many chemical reactions, causing its structure to change. Just like the principle of moisture-proof storage in "Tiangong Kaiwu", this substance should be stored in a dry environment, and the humidity should be controlled at 40% - 60%. If the environment is humid, water vapor is easy to adhere to it, or cause adverse reactions such as hydrolysis.
Furthermore, pay attention to sealed storage. Because it is volatile and may react with oxygen and other components in the air. Sealing can isolate the air and prevent it from contacting with external substances. Just like the method of sealing utensils in "Tiangong Kaiwu", a suitable container should be used to ensure good sealing. Glass or special plastic containers should be used. The lid is not easy to react with the substance because of its stable chemical properties. In this way, proper storage can ensure the quality and effectiveness of 2-butyl-1-H-imidazole-4 (5) -formaldehyde.