2-bromo-1H-imidazole-4,5-dicarbonitrile

2-Bromo-1H-imidazole-4,5-dicarbonitrile (2-bromo-1H-imidazole-4,5-dicarbonitrile) is an important organic compound with significant uses in many fields.
First, in the field of medicinal chemistry, this compound is a key intermediate. Due to the imidazole ring structure widely existing in many bioactive molecules, 2-bromo-1H-imidazole-4,5-dicarbonitrile has a specific functional group, which can be chemically modified to construct a variety of complex structures to develop new drugs. For example, for specific disease targets, by structural modification and optimization, highly active and highly selective drug molecules can be obtained, which brings new opportunities for disease treatment.
Second, it is also common in the field of materials science. With its unique chemical structure and properties, it can participate in the preparation of functional materials. For example, introducing it into polymer materials through specific reactions may endow the materials with special electrical and optical properties, such as the preparation of organic semiconductor materials with special photoelectric properties, which can be used in organic Light Emitting Diodes (OLEDs), solar cells and other devices to improve their performance and efficiency.
Furthermore, in the field of organic synthetic chemistry, 2-bromo-1H-imidazole-4,5-dinitrile can participate in a variety of organic reactions as a reaction substrate. Bromine atoms and dinitrile groups are active functional groups, which can undergo nucleophilic substitution, cyclization and other reactions, providing an effective way for the construction of complex organic molecular structures, assisting organic chemists in synthesizing various organic compounds with unique structures and properties, and promoting the development of organic synthetic chemistry.

2-Bromo-1H-imidazole-4,5-dinitrile is one of the organic compounds. Its physical properties are quite critical and are related to the basis of many chemical applications.
First of all, its appearance, under room temperature and pressure, is mostly white to light yellow solid powder. This color and shape are important characteristics for preliminary identification of this object, just like ancient people saw it, first observe its shape. Its texture is delicate, like the gathering of fine sand, the feeling of touch, and it is also different from other objects.
Furthermore, its melting point is within a specific temperature range. Determination of melting point is like detecting the properties of a substance. When the external temperature reaches this value, this substance will gradually melt from the solid state to the liquid state. Between this transformation, it contains changes in the internal structure of the substance. And this melting point value is stable and is not affected by small changes in the ordinary environment. It is like the strength of a rock, which can be used to identify the authenticity of this substance.
Solubility is also an important physical property. In common organic solvents, such as dichloromethane, N, N-dimethylformamide, etc., this substance exhibits a certain solubility. In dichloromethane, it is like a snowflake integrated into water and gradually dispersed to form a uniform solution. This is because the intermolecular forces between the two are in harmony with each other, like a tenon and mortise. However, in water, the solubility is not good, such as oil floating in water, the two are distinct, because the molecular structure of water molecules and the compound is very different, and it is difficult to be compatible.
In addition, the density of this substance also has characteristics. Although the density value is constant, it occupies a unique spatial position in the mixed system due to the different densities of other substances. In the process of separation and purification, this characteristic is very promising. For example, the ancients used the difference in the weight of objects to sort.
The physical properties of 2-bromo-1H-imidazole-4,5-dinitrile, such as appearance, melting point, solubility, density, etc., are related to each other, forming a unique physical "portrait" of this object. It is an indispensable key element in many fields such as chemical research and industrial production. Like a tool in the hands of a craftsman, it is difficult to do without one.

To prepare 2-bromo-1H-imidazole-4,5-dinitrile, the method is as follows:
First take an appropriate amount of 4,5-dinitrile-1H-imidazole and place it in a clean reaction vessel. This imidazole compound has relatively active properties and needs to be handled with care. Dissolve it in a suitable organic solvent, such as dichloromethane, to form a uniform solution. The choice of solvent should be good solubility to the reactants and no side reactions with the reactants.
Then, under low temperature, dark and stirring conditions, slowly add a brominating reagent. The brominating reagent can be selected from N-bromosuccinimide (NBS), etc. The low temperature state, about 0 ° C to 5 ° C, can make the reaction proceed smoothly and reduce the occurrence of side reactions. The rate of stirring, when moderate, allows the reactants to be fully mixed. This principle is due to the intense bromination reaction, low temperature and stirring can effectively control the reaction process. When adding the brominating reagent
, you need to add it dropwise, and you must not be too hasty. After each drop is added, wait for the reaction to stabilize slightly, and then add the next drop. This process requires close observation of reaction phenomena, such as changes in solution color, precipitation formation, etc. When the brominating reagent is added, keep stirring at low temperature for a period of time to complete the reaction.
After the reaction is completed, remove the organic solvent by appropriate methods, such as vacuum distillation, etc. Then, the product is purified by column chromatography and other separation methods. During column chromatography, a suitable eluent is selected to obtain a pure 2-bromo-1H-imidazole-4,5-dinitrile product. The whole process requires fine operation and attention to the control of reaction conditions to obtain ideal results.

2-Bromo-1H-imidazole-4,5-dinitrile is a chemical substance, and many matters need to be paid attention to during storage and transportation.
First, when storing, choose a dry, cool and well-ventilated place. This is because the substance may be quite sensitive to humidity and temperature. Humid and high temperature environments may cause it to deteriorate or cause chemical reactions. If it is in a humid place, moisture may interact with the substance, causing its chemical structure to change and damage its quality. Under high temperature, its chemical activity may increase or cause instability.
Second, it should be stored separately from oxidants, acids, bases and other substances. Due to its active chemical properties, contact with the above-mentioned substances is prone to violent chemical reactions, or even the risk of combustion and explosion. In case of strong oxidizing agents, or triggering oxidation reactions, a large amount of energy is released.
Third, the storage container must be well sealed. This can prevent substances from evaporating and escaping, and can also avoid the intrusion of impurities such as external air and moisture. It is also crucial to choose containers of suitable materials, such as glass or specific plastic materials, to ensure that they do not react with the substance.
Fourth, during transportation, ensure that the packaging is complete and firm. To prevent the packaging from being damaged due to bumps and collisions during transportation, so that the material leaks. At the same time, the transportation vehicle should be clean, dry, and free of other residues that may react with it. And transportation personnel need to be familiar with the characteristics of the substance and emergency treatment methods, so that in the event of an accident such as leakage, they can respond quickly and properly to reduce harm.

Today, I am asking about the market price of 2 - bromo - 1H - imidazole - 4,5 - dicarbonitrile. However, this is a fine chemical, and its market price often varies with quality, purity, supply and demand, purchase quantity and supplier, so it is difficult to determine the exact number.
If you want a high-purity product, its price is high. The preparation of fine chemicals often requires exquisite craftsmanship, which consumes manpower, material resources and financial resources. If the market demand for it is strong and the supply is limited, the price will also tend to be higher.
If the purchase volume is quite large, the supplier may give a certain discount because of small profits but quick turnover, and the price may be slightly reduced. And different suppliers have different pricing due to cost considerations and business strategies.
Therefore, if you want to know the exact market price, you can get a more accurate price by consulting chemical product suppliers, chemical trading platforms, or checking relevant market survey reports.