2 Benzyl 4 5 Dihydro 1h Imidazole Hydrochloride 1 1
quinoline thiophene imidazole thiazole

2-benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1)

    Specifications

    HS Code

    275977

    Chemical Formula C10H13ClN2
    Molar Mass 196.68 g/mol
    Appearance Solid
    Solubility In Water Soluble
    Physical State At Room Temperature Solid
    Odor Odorless (usually)
    Melting Point Data specific to this compound needed
    Boiling Point Data specific to this compound needed
    Density Data specific to this compound needed
    Ph In Solution Data specific to this compound needed

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    General Information
    Where to Buy 2-benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1) in China?
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    Frequently Asked Questions

    As a leading 2-benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1) supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2-benzyl-4, 5-dihydro-1H-imidazole hydrochloride (1:1)?
    2-Benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1), its chemical structure is as follows.
    This compound contains the core structure of imidazole, which is a five-membered heterocyclic ring with two nitrogen atoms. At the 4,5-position of 1H-imidazole, the dihydro state is also, that is, the carbon-carbon double bond of this two position is hydrogenated to form a single bond.
    At the 2-position, benzyl is connected. Benzyl is formed by connecting benzyl groups. The benzyl ring is a six-membered aromatic ring with a conjugated π electronic system, which imparts specific electronic properties and steric resistance to the molecule. The benzene ring is linked to the 2-position carbon of the imidazole ring by methylene (-CH 2O -).
    Furthermore, this compound is in the form of hydrochloride salt in a ratio of 1:1. That is, the nitrogen atom on the imidazole ring forms a cationic part by bonding with the hydrogen ion (H 🥰) dissociated by hydrochloric acid (HCl) by means of lone pair electrons, and the chloride ion (Cl) balances the charge with it to maintain electrical neutrality. This structure makes the compound have both the characteristics of the imidazole ring, the influence of benzyl group and the properties of salts, and has specific activities and applications in organic synthesis, medicinal chemistry and other fields.
    What are the main uses of 2-benzyl-4, 5-dihydro-1H-imidazole hydrochloride (1:1)?
    2-Benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1) has a wide range of uses. In the field of medicine, it can be an important intermediate for drug synthesis. With this substance, a variety of drugs with special pharmacological activities can be prepared, or used to treat specific diseases, such as certain neurological diseases, cardiovascular diseases, etc. Because of its structural properties, it can interact with specific targets in organisms to regulate physiological functions.
    In the field of organic synthesis, it is also a key raw material. Chemists can build complex organic molecular structures through various reactions according to their chemical properties, expand the variety of organic compounds, and lay the foundation for the research and development of new materials.
    In the field of materials science, materials made from this raw material may have unique physical and chemical properties, such as specific adsorption, stability, etc., and can be applied to fields such as separation membrane materials, adsorbents, etc., to help the development of related technologies.
    It is also indispensable in scientific research and exploration, providing a material basis for many studies, helping scientists to deeply explore chemical reaction mechanisms, biological activity mechanisms, etc., and promoting the progress and expansion of scientific knowledge.
    What are the physical properties of 2-benzyl-4, 5-dihydro-1H-imidazole hydrochloride (1:1)?
    2-Benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1), is an organic compound. It has many physical properties and is closely related to many chemical reactions and applications.
    The appearance of this compound is usually white to off-white crystalline powder. The cover is stable at room temperature and pressure due to the presence of specific functional groups in its structure, giving it a solid state appearance.
    Discuss solubility, which is soluble in water. In the molecular structure of the cover, the hydrochloride part can generate ion-dipole interaction with water molecules, which in turn makes the compound disperse in water and reach a dissolved state. At the same time, it also has a certain solubility in common organic solvents such as ethanol, because the organic part of the molecular structure can interact with organic solvents such as ethanol to produce van der Waals forces.
    Melting point is also an important physical property. Its melting point is about a specific value (the specific melting point needs to be accurately determined according to experiments), which is due to the strength of the intermolecular forces. When the temperature rises to the melting point, the molecule gains enough energy to overcome the intermolecular forces, thereby transforming from a solid state to a liquid state.
    In addition, the compound is hygroscopic. Because of the presence of a check point in its molecular structure that can form hydrogen bonds with water molecules, it is easy to absorb moisture in the air in a high humidity environment, resulting in its own deliquescence. This property requires attention during storage and use, and should be stored in a dry place.
    The physical properties of 2-benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1), such as appearance, solubility, melting point, and hygroscopicity, have a key impact on its application in chemical synthesis, drug discovery, and other fields.
    What is the synthesis method of 2-benzyl-4, 5-dihydro-1H-imidazole hydrochloride (1:1)?
    There are currently methods for preparing 2-benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1), which are described in detail as follows.
    Starting materials, benzyl glyoxal, ethylenediamine, etc. are often taken. When using benzyl glyoxal and ethylenediamine as raw materials, the two are put into a suitable reaction vessel, and an appropriate amount of solvent, such as alcohol solvent, methanol, ethanol, can be added. This solvent can provide a homogeneous environment for the reaction and help the reactants to fully contact.
    During the reaction, temperature control is required. Generally speaking, the temperature of the reaction system is raised to about 50-80 degrees Celsius, which allows the reaction to occur smoothly and increases the reaction rate. In the reaction, the carbonyl group of benzyl glyoxal and the amino group of ethylenediamine undergo condensation reaction to gradually form the structure of 2-benzyl-4,5-dihydro-1H-imidazole.
    After the reaction is basically completed, that is, after confirming that the reactants are exhausted and the amount of product formation does not increase by TLC (thin layer chromatography) or other suitable monitoring means, the reaction mixture needs to be treated. The reaction solution is first cooled to room temperature, and then an appropriate amount of hydrochloric acid solution is added dropwise. The amount of hydrochloric acid needs to be precisely controlled to achieve a stoichiometric ratio of 2-benzyl-4,5-dihydro-1H-imidazole to hydrochloric acid of 1:1. The dropwise addition process should be slow and stirred at the same time to
    With the addition of hydrochloric acid, 2-benzyl-4,5-dihydro-1H-imidazole hydrochloride is formed in the solution. At this time, the method of evaporating the solvent can be used to precipitate the product. The reaction solution is placed in a vacuum distillation device, heated appropriately, and the solvent is volatilized. As the solvent decreases, the product gradually crystallizes and precipitates. Finally, through conventional operations such as suction filtration, washing, and drying, a pure 2-benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1) product can be obtained. In this way, the desired compound is also obtained.
    2-Benzyl-4, 5-dihydro-1H-imidazole hydrochloride (1:1) What are the precautions during storage and transportation?
    2-Benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1) is a chemical and the like. During storage and transportation, many matters must not be ignored.
    First words storage. This medicine should be placed in a cool, dry and well-ventilated place. Cover a cool environment to avoid changes in the properties of the drug caused by excessive temperature. If heated, it may cause it to decompose and deteriorate, losing its original chemical properties and efficacy. A dry place can prevent moisture erosion. Because moisture can easily make the drug deliquescent, or cause chemical reactions, which will damage its quality. Well ventilated, it can keep the gas in the storage environment fresh and prevent the accumulation of harmful gases from affecting the drug.
    In addition, it must be kept away from fire sources and oxidants. This medicine may be flammable, and in case of open flames and hot topics, there is a risk of fire. Contact with the oxidant can easily trigger a violent oxidation reaction, endangering safety.
    As for transportation, the packaging must be solid and reliable. To ensure that the medicine is not damaged and there is no risk of leakage on the bumpy and vibrating road. The means of transportation should also be clean and dry to avoid mixing with other chemicals. To prevent interaction and accidental changes. During loading and unloading, the operation should be gentle, so as not to cause the packaging to collide or fall, causing damage to the medicine.
    In short, the storage and transportation of 2-benzyl-4,5-dihydro-1H-imidazole hydrochloride (1:1) must be based on its chemical properties and adhere to standards in order to ensure its quality and safety.