2-amino-1h-imidazole-5-dicarbonitrile

2-Amino-1H-imidazole-5-dicarbonitrile, Chinese name 2-amino-1H-imidazole-5-dimethylnitrile, this substance has a wide range of uses.
In the field of medicinal chemistry, it is often a key intermediate. By means of organic synthesis, it can be ingeniously converted into compounds with complex structures and specific biological activities through multi-step reactions. In the process of developing many new drugs, this is used as a starting material, modified and derived, and effective drugs for specific disease targets can be obtained. For example, in the development of antifungal drugs, based on the unique structure of this substance, through rational design and reaction, drugs with unique mechanisms of action on fungal cell walls or cell membranes can be prepared, interfering with the normal physiological activities of fungi, thereby achieving high-efficiency antifungal effects.
In the field of materials science, it also shows unique value. Due to the fact that its own structure contains groups such as nitrogen heterocycles and cyanyl groups, it can participate in the polymerization reaction under specific conditions to construct new polymer materials. Such materials may have excellent thermal stability, mechanical properties and electrical properties. For example, polymerization with some conjugated monomers is expected to generate materials with excellent photoelectric properties, which can be used in optoelectronic devices such as organic Light Emitting Diodes (OLEDs) or solar cells to improve device performance and efficiency.
In pesticide chemistry, it is also an important synthetic building block. Through appropriate chemical modification, new pesticides can be created. Its structure can be designed to interact with specific enzymes or receptors in pests, such as interfering with the signal transduction of the pest's nervous system, or inhibiting the activity of its key metabolic enzymes, so as to achieve the purpose of efficient insecticidal or deworming, and it is environmentally friendly and has low residues, which meets the needs of modern green pesticide development.

2 - amino - 1H - imidazole - 5 - dicarbonitrile, Chinese name 2 - amino - 1H - imidazole - 5 - dimethylnitrile, is an organic compound, which is widely used in the chemical and pharmaceutical fields. Its physical properties are as follows:
- ** Appearance properties **: At room temperature, it is mostly white to light yellow crystalline powder. This color state is easy to observe and distinguish. In production and experimental operations, its purity and quality can be preliminarily judged by its appearance. Powder is conducive to mixing with other substances to create convenience for subsequent chemical reactions.
- ** Melting boiling point **: Melting point is about 210 - 214 ° C. The melting point is relatively high, indicating that the intermolecular force is strong. This property makes the substance have good stability within a certain temperature range, and can maintain its own structure under specific chemical reaction conditions to ensure the precise progress of the reaction. Regarding the boiling point, due to the scarcity of relevant data, the exact value is difficult to determine. However, due to the fact that its structure contains polar groups such as nitrogen and cyanyl, there are hydrogen bonds and dipole-dipole interactions between molecules, and the boiling point should be higher.
- ** Solubility **: Slightly soluble in water, but easily soluble in organic solvents such as dimethyl sulfoxide (DMSO), N, N-dimethylformamide (DMF). Slightly soluble in water, due to the weak interaction between water molecules and the hydrogen bond formed by the compound. The organic solvent can rely on the principle of similar miscibility, and by virtue of its own polar or non-polar characteristics, form van der Waals forces with the molecules of the compound to promote its dissolution. This solubility is of great significance in organic synthesis, and a suitable solvent can be selected according to the reaction requirements to promote the smooth development of the reaction.
- ** Stability **: Under normal temperature and pressure, the substance is well stable. In case of open flame, hot topic, or contact with strong oxidants, there is a risk of chemical reactions. Because of its structure, cyanide groups have certain reactivity, and can participate in nucleophilic substitution, addition and other reactions under specific conditions. Therefore, when storing and using, be sure to keep away from fire sources, heat sources and strong oxidants to ensure safe operation.

To prepare 2-amino-1H-imidazole-5-dinitrile, the following ancient method can be used.
First, suitable starting materials, such as nitrogen-containing heterocyclic precursors and cyanide-containing reagents. First, the nitrogen-containing heterocyclic precursors, such as a specific imidazole derivative, are carefully placed in a clean reaction vessel. This container must be dry and airtight to prevent impurities from invading.
Then, slowly add cyanide-containing reagents, such as potassium cyanide or other cyanide sources. When adding, pay attention to the rate to maintain a smooth reaction. During the addition process, it is recommended to maintain a low temperature environment, about in an ice bath, which can allow the reaction to proceed accurately and reduce the generation of side reactions.
Subsequently, an appropriate amount of catalyst is added. This catalyst should be able to effectively promote the reaction and speed up the process. And its dosage must be precisely controlled. More than excessive catalysis causes an increase in by-products, and less than slow reaction.
After that, the reaction system is heated to an appropriate temperature. The choice of this temperature is very critical, depending on the raw materials and reaction characteristics, usually between tens of degrees Celsius and more than 100 degrees Celsius. Maintain this temperature and continue to stir to fully contact the reactants to accelerate the completion of the reaction.
During the reaction, it should be monitored regularly. The reaction process can be observed by thin-layer chromatography or other suitable analytical means. When the reaction reaches the desired level, the heating is stopped and the reaction system is slowly cooled.
After cooling, extract with a suitable solvent. When choosing a solvent, consider the solubility of the product and the convenience of separation. After extraction, the organic phase is dried, and a desiccant such as anhydrous sodium sulfate can be added to remove water.
Finally, the pure 2-amino-1H-imidazole-5-dinitrile product is obtained by distillation, recrystallization and other purification methods. During operation, care must be taken to prevent product loss or the introduction of new impurities. In this way, a qualified target product can be obtained.

2-Amino-1H-imidazole-5-dimethylnitrile, this compound is used in many fields.
In the field of medicine, it can be used as a key intermediate. Physicians want to make specific drugs, often rely on this compound as a starting material, and through multiple steps of delicate reactions, they can obtain drugs with unique effects. For example, some antibacterial drugs, with the special structure of 2-amino-1H-imidazole-5-dimethylnitrile, fit with the key targets in bacteria, blocking the pathway of bacterial growth and metabolism, making it difficult for bacteria to wreak havoc and achieve the effect of healing and saving people.
In the field of materials science, it also has extraordinary performance. Craftsmen integrate it into a specific material system to improve the properties of the material. Or enhance the stability of the material to make the material durable in different environments; or endow the material with special optical and electrical properties, such as for the preparation of new photoelectric materials, so that the material can perceive light signals and accurately convert them into electrical signals, making it useful in the manufacture of optoelectronic devices.
It can also be seen in the research and development of pesticides. Farmers want to protect crops from insect infestation, and researchers use 2-amino-1H-imidazole-5-dimethylnitrile as a base to create targeted pesticides. Such pesticides can precisely act on the specific physiological processes of pests, or damage the nervous system of pests, making them disordered; or interfere with the respiratory system of pests, making them difficult to survive and effectively protecting farmland crops.
From this point of view, 2-amino-1H-imidazole-5-dimethonitrile is of great value in the fields of medicine, materials science, pesticide research and development, and is actually a widely used compound.

2-Amino-1H-imidazole-5-dimethylnitrile is a special organic compound. In the current market situation, its use is quite extensive. In the field of medicinal chemistry, it is often used as a key intermediate to assist in the synthesis of many drugs with specific biological activities. Due to its unique chemical structure, it can impart special properties to drug molecules, thereby enhancing the efficacy of drugs.
In the field of materials science, 2-amino-1H-imidazole-5-dimethylnitrile has also emerged. Researchers have found that it can participate in the preparation process of some high-performance materials, enhancing the stability and functionality of materials.
At the market supply level, some professional chemical reagent suppliers will provide this compound, but its production process has certain complexity, so the output is not extremely impressive. In terms of price, it is in a relatively high range due to factors such as raw material cost and synthesis difficulty.
In terms of demand situation, with the rapid development of pharmaceutical research and development and materials science, the demand for 2-amino-1H-imidazole-5-dimethanonitrile is rising steadily. However, due to the limitation of production technology, there is still a certain gap between market supply and demand. This gap may prompt more researchers and enterprises to devote themselves to the optimization and innovation of relevant synthesis processes, in order to increase production and meet the growing market demand.