2 Amino 1h Imidazole 4 Carboxylic Acid Ethyl Ester
quinoline thiophene imidazole thiazole

2-amino-1H-imidazole-4-carboxylic acid ethyl ester

    Specifications

    HS Code

    899235

    Chemical Formula C6H9N3O2
    Molar Mass 155.155 g/mol
    Appearance Solid (presumed, common for such compounds)
    Solubility Solubility characteristics would depend on solvent, but generally sparingly soluble in non - polar solvents, more soluble in polar protic solvents like water and alcohols
    Melting Point No specific data provided, but similar imidazole - based esters may have melting points in the range of 100 - 200 °C
    Boiling Point Estimated to have a boiling point at elevated temperatures under normal pressure considering its molecular weight and structure
    Density No exact density data, but likely in the range of 1 - 1.3 g/cm³ based on similar organic compounds
    Acidity Basicity The amino group can act as a base, and the imidazole ring can also participate in acid - base reactions
    Stability Stable under normal conditions, but can react under strong acidic, basic or oxidative/reductive conditions
    Reactivity Can undergo hydrolysis in the presence of acids or bases to form the corresponding carboxylic acid and ethanol, can react with electrophiles due to the presence of nitrogen atoms in the imidazole and amino groups

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    Frequently Asked Questions

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    What are the chemical properties of 2-amino-1H-imidazole-4-carboxylic acid ethyl ester
    2-Amino-1H-imidazole-4-carboxylic acid ethyl ester, this is an organic compound. Looking at its structure, it contains an imidazole ring. This ring is a five-membered nitrogen-containing heterocycle with certain aromaticity, giving the compound unique stability and electronic characteristics.
    In terms of physical properties, under normal temperature and pressure, it may be a white to light yellow crystalline powder. Due to the presence of polar groups, it may have a certain solubility in polar solvents such as water and alcohols.
    In terms of chemical properties, amino groups (-NH2O) are basic and can be neutralized with acids to form salts. In case of hydrochloric acid, lone pairs of electrons on the amino nitrogen atom can bind protons to form corresponding ammonium salts.
    Esteryl groups (- COOCH < Br > CH < Br >) are active and easy to hydrolyze, and can be carried out under acidic or basic conditions. In acidic hydrolysis, 2-amino-1H-imidazole-4-carboxylic acids and ethanol are formed; in basic hydrolysis, 2-amino-1H-imidazole-4-carboxylate and ethanol are formed, and the hydrolysis is more complete under basic conditions.
    In addition, the nitrogen atom on the imidazole ring has lone pair electrons, which can participate in the coordination reaction and form complexes with metal ions. This property may have applications in the fields of materials science and bioinorganic chemistry. Due to its unique structure, it can be used as a key intermediate in organic synthesis for the preparation of more complex imidazole-containing compounds, which may have potential biological activity in the field of medicinal chemistry or can be developed into new drugs.
    What are the synthesis methods of 2-amino-1H-imidazole-4-carboxylic acid ethyl ester
    The synthesis of 2-amino-1H-imidazole-4-carboxylic acid ethyl ester is a key research direction in the field of chemistry. There are various synthesis paths, so let me tell you in detail.
    First, the corresponding imidazole carboxylic acid can be started from the corresponding imidazole carboxylic acid and esterified to form this ester. First, take the imidazole carboxylic acid, place it in a suitable reaction vessel, add an appropriate amount of ethanol as an esterification reagent, and introduce a catalyst such as concentrated sulfuric acid. Under the state of heating and reflux, the carboxylic acid and ethanol undergo esterification reaction, and the reaction system gradually approaches equilibrium after several years. After the reaction is completed, 2-amino-1H-imidazole-4-carboxylic acid ethyl ester can be obtained by a series of post-treatment methods such as neutralization, extraction, and distillation.
    Second, the imidazole ring can also be constructed from the beginning. Under specific reaction conditions, the imidazole ring structure is first constructed with suitable nitrogen and carbon-containing raw materials, such as glyoxal, cyanamide, and ethyl acetate. In an alkaline environment, glyoxal and cyanamide are condensed, and then reacted with ethyl acetate. After cyclization and aminolysis, the target product is gradually formed. This process requires precise control of reaction conditions, such as temperature, pH, reaction time, etc. A slight difference in the pool will affect the yield and purity of the product.
    In addition, transition metal catalysis can also be used. Transition metal catalysts such as palladium and copper are selected, and specific ligands are used to promote the coupling reaction of imidazole-containing substrates with halogenated ethyl acetate or other suitable electrophilic reagents. The reaction conditions in this way are relatively mild and the selectivity is quite high. However, the cost of transition metal catalysts is high, and subsequent separation is also difficult, which needs to be properly disposed of.
    All these synthesis methods have their own advantages and disadvantages. In practical applications, when considering the availability of raw materials, cost considerations, product purity requirements, and many other factors, a suitable synthesis path is carefully selected to achieve the purpose of efficient, economical, and environmentally friendly synthesis.
    2-amino-1H-imidazole-4-carboxylic acid ethyl ester is used in which areas
    2-Amino-1H-imidazole-4-carboxylic acid ethyl ester, this is an organic compound. It has applications in many fields.
    In the field of medicine, because of its specific chemical structure and properties, it can be used as a key intermediate in drug synthesis. With this structure, it can participate in a series of chemical reactions to construct complex drug molecules with biological activity. For example, in the development of some new drugs for the treatment of specific diseases, it is used as a starting material to introduce other functional groups through carefully designed reaction steps to prepare drugs with high affinity and activity to specific targets, which is expected to bring new opportunities for disease treatment.
    In the field of materials science, it also has unique uses. Polymer materials with special properties can be prepared by polymerizing with other monomers through specific reactions. For example, by rationally designing the polymerization reaction conditions and formulations, the resulting materials may have unique thermal stability, mechanical properties or optical properties, etc., which can be used to make special plastics, fibers or optical materials to meet different industrial needs.
    In the field of agricultural chemistry, 2-amino-1H-imidazole-4-carboxylate ethyl ester can be used as a raw material for the synthesis of new pesticides or plant growth regulators. By modifying and modifying its chemical structure, pesticides that have efficient control of crop diseases and pests and are environmentally friendly, or regulators that can precisely regulate the growth and development process of plants, can be synthesized to help sustainable agricultural development.
    In addition, in the study of organic synthetic chemistry, it is often used as an important reagent to explore novel chemical reaction paths and methods. With its unique structure, researchers have carried out various reaction mechanism studies, promoted the theoretical and practical progress of organic synthetic chemistry, and provided new ideas and methods for the synthesis of more complex organic compounds.
    What is the market price of 2-amino-1H-imidazole-4-carboxylic acid ethyl ester
    2-Amino-1H-imidazole-4-carboxylic acid ethyl ester, the price of this product in the city is determined, which involves many factors and is difficult to generalize.
    The price of raw materials is one of the main reasons for the appearance of the Guanfu chemical market. If the raw materials for synthesizing this ester are widely sourced and affordable, the cost of this ester is also low, and the price is close to the people. On the contrary, if the raw materials are rare and difficult to find, the price will be high.
    Furthermore, the complexity of the process is also related to the price. If the preparation method is simple, energy consumption is low, and labor is saved, the cost is controllable, and the price in the city may be appropriate. If you need exquisite art, harsh environment, many twists and turns can be achieved, and the price is high.
    And the supply and demand of the market, the price is very huge. If there are many people in need, but the production is insufficient, the merchant will raise the price to make a profit. If the supply exceeds the demand, the stock is full, and the merchant may reduce the price to promote.
    The difference in the region also makes the price different. Prosperous and well-connected places, convenient logistics, smooth trade, or because of competition, the price may be reasonable. And remote places, difficult transshipment, and all the costs, the price may be high.
    From this perspective, in order to know the exact market price of 2-amino-1H-imidazole-4-carboxylic acid ethyl ester, it is necessary to carefully observe the price of raw materials, the state of technology, the state of supply and demand, and the differences in regions.
    What are the storage conditions for 2-amino-1H-imidazole-4-carboxylic acid ethyl ester?
    2-Amino-1H-imidazole-4-carboxylic acid ethyl ester, this is an organic compound. Depending on its storage conditions, the following points should be carefully paid attention to.
    Bear the brunt and need to be placed in a cool place. Because if it is heated, or the molecular movement intensifies, triggering a chemical reaction and causing its properties to change. In a cool place, the temperature is relatively stable, which can reduce the risk of temperature fluctuations.
    Furthermore, be sure to keep it dry. If this compound encounters water vapor, it may hydrolyze, destroying its molecular structure and damaging its quality. Therefore, the storage environment should be protected from moisture, and the environment can be maintained dry with the help of desiccants.
    In addition, pay attention to isolating the air. Oxygen and other components in the air may react with the compound such as oxidation. Store in a sealed container to reduce its contact with the air and maintain its chemical stability.
    In addition, this compound may have certain toxicity or irritation, and should be stored separately from food, medicine, etc., and away from fire and heat sources to prevent safety accidents due to unexpected conditions.
    Store 2-amino-1H-imidazole-4-carboxylate ethyl ester, create a cool, dry, sealed environment, and do a good job of safety protection, so as to ensure its quality and safety.