2 4 Bromophenyl 1 Phenyl 1h Benzoimidazole
quinoline thiophene imidazole thiazole

2-(4-Bromophenyl)-1-phenyl-1H-benzoimidazole

    Specifications

    HS Code

    599937

    Chemical Formula C20H13BrN2
    Molar Mass 361.234 g/mol
    Appearance Solid (likely white to off - white powder)
    Melting Point Specific value would require experimental determination
    Boiling Point Specific value would require experimental determination
    Solubility In Water Low (due to non - polar nature of large aromatic groups)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Density Specific value would require experimental determination
    Uv Vis Absorption Absorption bands in UV region due to conjugated aromatic system

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    General Information
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    Frequently Asked Questions

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    What are the main uses of 2- (4-bromophenyl) -1-phenyl-1H-benzimidazole?
    2-%284-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1-%E8%8B%AF%E5%9F%BA-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91, this is a chemical substance related expression. After analysis, it may be a structural simple expression of a complex organic compound. 2 - (4-hydroxybenzyl) -1-benzyl-1H-benzimidazole, such substances have important uses in many fields.
    In the field of medicine, it shows potential effects of antibacterial, antiviral and anti-tumor. Studies have shown that the specific structure of the substance can bind to some key targets in organisms, thereby inhibiting the growth and reproduction of bacteria, or inducing tumor cell apoptosis, providing valuable lead compounds for the development of new drugs. < Br >
    In the field of materials science, it can be used as a functional additive. Due to its structural properties, it can improve the stability, oxidation resistance and optical properties of materials. For example, when added to polymer materials, it can enhance the ability of materials to resist external environmental erosion and prolong the service life of materials; when applied to optical materials, it can improve the optical transmittance and refractive index of materials.
    It also has potential applications in agriculture. It can be used as a plant growth regulator to regulate the growth and development process of plants, improve the resistance of plants to diseases and pests, and promote crop production and income. Because of its unique chemical structure, it can simulate the action of certain hormones in plants and precisely regulate plant physiological activities.
    In summary, 2- (4-hydroxybenzyl) -1-benzyl-1H-benzimidazole plays an important role in many fields such as medicine, materials science and agriculture due to its unique chemical structure, and has broad application prospects and research value.
    What are the synthesis methods of 2- (4-bromophenyl) -1-phenyl-1H-benzimidazole
    To prepare 2 - (4 -quinolinyl) -1 -quinoline-1H -quinopyridine compounds, there are many synthesis methods, which are described in detail below.
    First, using nitrogen-containing heterocycles as the starting material, the key skeleton is built by nucleophilic substitution reaction. First, a suitable halogenated aromatic hydrocarbon and nitrogen heterocycles are co-heated in the presence of a base and a catalyst, and undergo nucleophilic substitution to form an intermediate product. Then, the intermediate product undergoes cyclization reaction under specific conditions to construct the quinopyridine structure of the target compound. For example, select an appropriate halogenated quinoline and another active nitrogen heterocycle, and reflux in a high-boiling organic solvent under the action of a base such as potassium carbonate and a copper catalyst to promote nucleophilic substitution; after heating or adding a specific cyclization reagent, cyclization is achieved to complete the synthesis.
    Second, a coupling reaction strategy catalyzed by transition metals is adopted. Halogenated quinoline derivatives and alkenyl or alkynyl quinoline derivatives are used as substrates, and in the presence of transition metal catalysts and ligands such as palladium and nickel, coupling reactions occur. Like the classic Heck reaction, Sonogashira reaction, etc., can effectively connect different fragments. Taking the Heck reaction as an example, haloquinoline and alkenyl quinoline are heated in an appropriate solvent under the combined action of palladium catalyst, base and ligand to form an intermediate connected by carbon-carbon double bond. After further intramolecular cyclization, the target 2 - (4 - quinolinyl) -1 - quinoline - 1H - quinopyridine compounds are obtained.
    Third, through intramolecular cyclization condensation reaction. Select linear precursor molecules with suitable functional groups, such as those containing multiple amino, carbonyl or halogen atoms and other active groups. Under the action of acids, bases or specific condensing agents, these precursor molecules first undergo intermolecular condensation to form larger molecular structures, and then undergo intramolecular cyclization under the induction of heat, light or catalysts to form target compounds. For example, quinoline derivatives containing ortho-amino and carbonyl groups, under the catalysis of acids, the amino and carbonyl groups are condensed, and then cyclized to form quinopyridine structures.
    These three types of methods are common ways to synthesize 2- (4-quinolyl) -1-quinoline-1H-quinopyridine compounds. In practice, the most suitable method should be selected according to the availability of raw materials, the difficulty of reaction conditions and the purity of the target product.
    What are the physical properties of 2- (4-bromophenyl) -1-phenyl-1H-benzimidazole?
    2-%284-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1-%E8%8B%AF%E5%9F%BA-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91%E7%9A%84%E5%88%86%E5%AD%90%E5%BC%8F%E4%B8%BA $C_ {10} H_ {12} O_2 $, which is a compound having the following physical properties:
    This substance is often in the form of a liquid under normal conditions, with certain properties, and can disperse a special fragrance, often used as a perfume component. Its boiling temperature is usually at a certain temperature, because it has certain properties, it can be reduced by a liquid. The melting phase is low, generally below normal temperature, and often holds a liquid under normal conditions.
    In terms of solubility, 2-%284-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1-%E8%8B%AF%E5%9F%BA-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91 soluble in water, because of the large proportion of carbon segments in the molecule, which is hydrophobic, and the water molecules are weak in the action of the two, so they are soluble. However, this material is easily soluble in many soluble substances, such as ethanol, ether, etc., because the molecular forces of the soluble molecules are similar, and follow the principle of "similar phase dissolution".
    Its density is usually slightly smaller than that of water. If water is mixed, it will float on the water surface. The amount of molecular phase and the arrangement of molecules make the amount of molecular phase smaller than that of water. 2-%284-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1-%E8%8B%AF%E5%9F%BA-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91 has a certain refractive property. The light is passed through the water, and the direction of propagation is changed. The refractive index is fixed at a fixed value under a specific component, which can be used as one of the dependencies of a fixed substance. In addition, this substance is determined in general conditions, but in specific components, such as high temperature and catalysis, it can be biochemically reversed and synthesized.
    What are the chemical properties of 2- (4-bromophenyl) -1-phenyl-1H-benzimidazole?
    2-% (4-cyanobenzyl) -1-benzyl-1H-benzimidazole is a class of organic compounds with unique chemical properties and considerable research value.
    This compound contains functional groups such as cyano and benzimidazole, which endow it with various chemical activities. Cyanyl groups have strong electron-withdrawing properties and can significantly affect the electron cloud distribution of molecules, which in turn makes the compound exhibit special reactivity. For example, in nucleophilic substitution reactions, the presence of cyano groups can enhance the reactivity at certain positions on the benzene ring, making it easier for nucleophiles to attack specific check points.
    The structure of benzimidazole is the core part of this compound, which has certain alkalinity and coordination ability. It can be used as a ligand to coordinate with a variety of metal ions to form complexes with specific structures and functions. These complexes have potential applications in catalysis, materials science and many other fields. For example, in catalytic reactions, it can play a catalytic role in specific chemical reactions by virtue of its unique structure and electronic properties, improving the reaction rate and selectivity.
    At the same time, the introduction of 1-benzyl groups also has an important impact on the physical and chemical properties of compounds. The steric resistance effect of benzyl groups affects the interaction between molecules, and its electronic effect also affects the reactivity of benzimidazole rings. In some chemical reactions, benzyl can play the role of protecting the group and avoid unnecessary reactions at specific positions on the benzimidazole ring. When the reaction is completed, the benzyl group can be removed by specific methods to obtain the target product.
    In the field of organic synthesis, 2% (4-cyanobenzyl) -1-benzyl-1H-benzimidazole is often used as a key intermediate to participate in the construction of various complex organic molecules. Using the reactivity of different functional groups, it can achieve precise modification and construction of molecular structures through a series of organic reactions, such as nucleophilic substitution, addition reaction, etc., providing an important basis for the synthesis of organic compounds with specific biological activities or material properties.
    What is the price range of 2- (4-bromophenyl) -1-phenyl-1H-benzimidazole in the market?
    Looking at what you said, I seem to be asking "the price of 2- (4-benzyl) -1-benzyl-1H-indolocarbazole in the market". However, this is a rather professional chemical, and its price range is difficult to describe in a single word.
    The price of
    covers its price is affected by many factors. First, purity is essential. If the purity is extremely high, it is almost perfect, and it can be used for high-end purposes such as scientific research, the price will be high; if the purity is slightly lower, it is only suitable for general experiments or basic research, and the price may be slightly lower. Second, the yield also affects it. If mass production, due to the scale effect, the unit cost may decrease, and the price will also decrease; if the output is scarce and the supply is in short supply, the price will rise. Third, the difficulty of preparation is also related. If the preparation process is complicated, special raw materials, high-end equipment and exquisite skills are required, and the cost is high and the price is expensive; if the preparation is relatively simple, the price may be close to the people.
    Although it is difficult to determine the range of its price, as far as I know, such professional chemicals used in scientific research range from hundreds to thousands of yuan per gram. If it is for industrial use and the purity requirements are slightly lower, the price may decrease, but it also depends on the specific market supply and demand and production conditions.