2 4 Bromo Phenyl 1h Imidazole
quinoline thiophene imidazole thiazole

2-(4-BROMO-PHENYL)-1H-IMIDAZOLE

    Specifications

    HS Code

    535727

    Chemical Formula C9H7BrN2
    Molar Mass 223.07 g/mol
    Appearance Solid
    Solubility Solubility in organic solvents like DMSO, limited in water
    Purity Typically sold as high - purity compound (e.g., 95%+)
    Synthesis Method Can be synthesized through multi - step organic reactions involving bromination and imidazole formation steps
    Stability Stable under normal conditions, away from strong oxidizing agents

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    General Information
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    Frequently Asked Questions

    As a leading 2-(4-BROMO-PHENYL)-1H-IMIDAZOLE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the physical properties of 2- (4-bromophenyl) -1H-imidazole?
    2-%284-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1H-%E5%92%AA%E5%94%91%E7%9A%84%E5%85%A8%E7%A7%B0%E4%B8%BA2 - (4-bromobenzyl) -1H-indole, this is an organic compound. Its physical properties are as follows:
    - ** Appearance and Properties **: Usually in the state of white to light yellow crystalline powder. This form is easy to observe and operate, and in many chemical reactions and experiments, this appearance helps to distinguish and use it.
    - ** Melting point **: about 136 - 139 ° C. The melting point is an important physical property of the substance. At this temperature, the compound exists stably in solid form; once the melting point is reached, it will gradually transform into a liquid state. By accurately measuring the melting point, its purity can be effectively judged. The higher the purity, the narrower the melting point range.
    - ** Solubility **: Soluble in common organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. This property makes it widely used in the field of organic synthesis. It can participate in various reactions in different organic solvent systems. With good solubility, the molecules can be uniformly dispersed, thus promoting the efficient progress of the reaction. However, its poor solubility in water is mainly due to the dominant position of hydrophobic groups in the molecular structure of the compound, resulting in weak forces with water molecules. < Br > - ** Stability **: Under normal storage and use conditions, it has certain stability. However, it is necessary to avoid contact with strong oxidants, strong acids, strong bases and other substances, otherwise chemical reactions will easily occur, resulting in structural changes. When storing, it should be placed in a cool, dry and well-ventilated place to prevent moisture, heat and other factors from affecting its stability.
    What are the chemical properties of 2- (4-bromophenyl) -1H-imidazole?
    2- (4-cyanobenzyl) -1H-imidazole is an organic compound with a variety of chemical properties.
    It is weakly basic, because the imidazole ring contains nitrogen atoms, has lone pairs of electrons, accepts protons, and can form salts in acidic environments. For example, in the case of strong acids, it can form corresponding salts.
    2- (4-cyanobenzyl) -1H-imidazole contains unsaturated bonds, such as the double bond of the imidazole ring and the triple bond of the cyanyl group, which can undergo an addition reaction. Taking the cyanyl group as an example, under specific catalysts and conditions, it can be added with hydrogen to form an amino group.
    The cyanyl group of this compound can also be hydrolyzed. Under the catalysis of acid or base, the cyanyl group can be gradually converted into a carboxylic group, which first generates an amide intermediate and finally becomes a carboxylic acid.
    In addition, 2- (4-cyanobenzyl) -1H-imidazoline contains multiple active check points and can participate in the substitution reaction. For example, the hydrogen atom on the imidazole ring can be replaced by other groups under appropriate reagents and conditions.
    Due to the conjugated structure of benzene ring and imidazole ring in the molecule, 2- (4-cyanobenzyl) -1H-imidazole has certain stability and conjugation effect, which affects its physical and chemical properties, such as the melting point, boiling point and electron cloud distribution of the compound, which in turn affects the reactivity and selectivity.
    What is the main synthesis method of 2- (4-bromophenyl) -1H-imidazole?
    2-%284-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1H-%E5%92%AA%E5%94%91%E7%9A%84%E5%90%88%E6%88%90%E6%96%B9%E6%B3%95%E5%A4%9A%E7%A7%8D%E5%A4%9A%E6%A0%B7, the following is a common method:
    First, use appropriate raw materials to construct the basic skeleton through multi-step reaction. For example, the compound containing a specific functional group is first taken, and the molecules are gradually derived by means of nucleophilic substitution, addition and other reactions. In the early steps, the reaction conditions and reagents are carefully selected to ensure the selectivity and yield of the reaction.
    When constructing the 4-bromobenzyl moiety, it can start from a suitable aromatic hydrocarbon, introduce bromine atoms through bromination reaction, and then access the benzyl structure through alkylation reaction. For the modification of the 2-moiety, the appropriate reaction path needs to be selected according to the overall molecular design. The formation of the
    1H-indole structure is often a key step. It can be formed by the cyclization reaction of o-amino benzaldehyde or its derivatives with carbonyl-containing compounds. The control of this cyclization reaction conditions is very important, such as temperature, catalyst type and dosage, which will affect the reaction process and product purity. In the reaction, the catalyst can be selected from Lewis acid or proton acid, etc., and the choice is optimized according to the characteristics of the substrate.
    During the synthesis process, the reaction process needs to be closely monitored. The reaction is often tracked by thin-layer chromatography (TLC). When the reaction reaches the expected level, post-treatment is carried out in a timely manner. Post-treatment includes extraction, washing, drying, column chromatography separation and other steps to obtain a pure product.
    The synthesis process should also pay attention to safety and environmental protection. When selecting reagents and reaction conditions, try to avoid highly toxic and highly polluted materials, and optimize the reaction process to reduce waste generation, making the synthesis path greener and more sustainable. In this way, through multiple steps of exquisite design and operation, the target product 2 - (4-bromobenzyl) -1H-indole can be obtained.
    In what fields is 2- (4-bromophenyl) -1H-imidazole used?
    2-%284-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1H-%E5%92%AA%E5%94%91, that is, 2- (4-thiophenyl) -1H-pyrazole, this compound has applications in the fields of medicine, pesticides and materials.
    In the field of medicine, it has attracted much attention in drug development because of its unique chemical structure and biological activity. It can be used as a key intermediate to synthesize compounds with specific pharmacological activities. For example, in the development of anti-tumor drugs, researchers hope to obtain new drugs with high selective inhibitory effect on tumor cells by modifying and optimizing their structures. Some compounds containing thiophenyl and pyrazole structures can affect the proliferation and apoptosis-related signaling pathways of tumor cells through specific mechanisms, providing new directions for the development of anti-tumor drugs.
    In the field of pesticides, 2- (4-thiophenyl) -1H-pyrazole can be used as a lead compound to create new pesticides. The structure of thiophenyl and pyrazole gives it certain insecticidal and bactericidal activities. Based on its structural modification and optimization, it is expected to develop high-efficiency, low-toxicity and environmentally friendly pesticides. For example, some compounds containing such structures show good repellent and poisoning effects on some crop pests, and can be used for crop pest control to ensure crop yield and quality.
    In the field of materials, due to its special molecular structure and properties, it may have potential applications in organic optoelectronic materials. For example, in the research of organic Light Emitting Diode (OLED) materials, the introduction of this structural unit can regulate the electronic transport and luminescence properties of the materials, improve the luminous efficiency and stability of OLED devices, and provide new ideas and approaches for the development of new organic optoelectronic materials.
    What is the market price of 2- (4-bromophenyl) -1H-imidazole?
    I think what you are asking is about the market price of 2- (4-cyano) -1H-indole. However, the price of this product often changes for many reasons, and it is difficult to determine its fixed number.
    The market price is mainly related to supply and demand. If there are many people who want it, but there are few suppliers, the price will increase; on the contrary, if the supply exceeds the demand, the price will drop. And the difficulty and cost of its preparation are also the key. If the preparation is complicated, the required raw materials are expensive, and the process is strict, the cost will be high, and the market price will also be high.
    Furthermore, the price varies from place to place and at different times. In the bustling city, due to the concentration of demand and active business, the price may be different; in remote places, or due to logistics inconvenience, the price may also be different. The change of time, the innovation of technology, and the rise and fall of raw materials can all cause the price to change.
    If you want to know the exact market price, you should carefully observe the dynamics of the chemical market, consult industry experts, or visit the chemical trading platform, so that you can get a more accurate price. However, it is difficult for me to give you a definite number at this time. I hope you can find the required price according to this route.