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What are the main uses of 2- (4-aminophenyl) -5-aminobenzimidazole?
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First, in the field of medicine, 2- (4-hydroxyphenyl) -5-hydroxybenzofuranone can be used to synthesize drugs with specific therapeutic effects. According to traditional medicinal chemistry theory, the unique structure of the compound may interact with specific targets in vivo. If the occurrence of certain diseases is related to the abnormal activity of specific proteins or enzymes, the structure of this compound may fit the target, regulate its activity, and achieve the purpose of treating diseases. For example, in the development of anti-cancer drugs, studies have found that it may affect the proliferation, differentiation and apoptosis-related signaling pathways of cancer cells, providing a new direction for the development of anti-cancer drugs.
Second, in materials science, it also has potential applications. Because it contains specific functional groups, it can be introduced into polymer materials through chemical reactions to give new properties to the materials. For example, adding this compound to polymer materials may improve the antioxidant properties of the materials. When the material is exposed to air and other environments, oxidation reactions are prone to occur and the properties are deteriorated. The antioxidant properties of the compound may effectively inhibit the oxidation process and prolong the service life of the material. It has application potential in plastic products, fiber materials and other fields.
Third, in the field of organic synthesis, 2- (4-hydroxyphenyl) -5-hydroxybenzofuranone is often used as a key intermediate. Organic synthesis aims to build complex organic molecules. Due to its structural characteristics, this compound can react with other organic reagents through various chemical reactions, such as esterification, etherification, alkylation, etc., to build more complex organic compound structures, providing an important foundation for the synthesis of new organic functional materials and the total synthesis of natural products.
What are the synthesis methods of 2- (4-aminophenyl) -5-aminobenzimidazole
To prepare 2- (4-aminophenyl) -5-aminobenzolidone, the synthesis method is as follows:
First, o-phenylenediamine and urea are used as starting materials, and the condensation reaction is carried out under appropriate reaction conditions. Under the environment of high temperature and suitable catalyst, the carbonyl group in urea and the amino group of o-phenylenediamine condensate to gradually form the basic skeleton structure of benzimidazolidone. This process requires strict control of temperature and reaction time. If the temperature is too high or the time is too long, side reactions may occur, which affects the purity and yield of the product.
Next, the obtained benzimidazolidone intermediate is modified by amination. Appropriate amination reagents, such as certain compounds containing amino groups, are used, and appropriate reaction solvents and reaction conditions are selected. During the reaction, it is necessary to precisely control the dosage of reagents and the pH of the reaction environment, because pH has an important impact on the selectivity of the check point of the amination reaction. If the conditions are improper, excess or wrong amino groups may be introduced into the structure of benzimidazolone, resulting in impure products.
During the entire synthesis process, after each step of the reaction, the product should be purified by separation and purification methods such as recrystallization and column chromatography to remove unreacted raw materials, by-products and catalysts and other impurities. To ensure the purity of the intermediate at each step, it is necessary to lay the foundation for the final high-purity 2- (4-aminophenyl) -5-aminobenzimidazolone. At the same time, the reaction equipment needs to be kept clean to avoid impurities from mixing into the reaction system and affecting the reaction process and product quality.
What are the physicochemical properties of 2- (4-aminophenyl) -5-aminobenzimidazole?
2 - (4 -Aminophenyl) -5 -Aminobenzothiazole is an organic compound. Its physical and chemical properties are unique and are described in detail as follows:
Appearance properties: It is often in solid form, the specific color varies depending on the purity and preparation conditions, or it is a white to light yellow powdery solid with fine texture.
Melting point and boiling point: In view of the intermolecular force and structural characteristics of the compound, it has a specific melting point and boiling point. The exact value has been determined by experiments. The melting point is about [X] ° C. At this temperature, the lattice can be overcome, and the solid state is converted into a liquid state; the boiling point is about [X] ° C. At that time, the molecule obtains enough energy to break free from the liquid phase and transform into a gaseous state.
Solubility: Different solubility in organic solvents. In common organic solvents such as dichloromethane, N, N-dimethylformamide (DMF), it exhibits a certain solubility. Because of this, the structure of the compound and the molecules of the organic solvent can form interactions such as van der Waals force, hydrogen bond, etc., thereby enhancing dissolution. However, the solubility in water is poor, because of its large proportion of hydrophobic groups in the molecule, and the weak force between water molecules, it is difficult to form a stable dispersion system.
Stability: relatively stable at room temperature and pressure. However, in case of strong oxidizing agents, strong acids, strong bases and other specific chemical reagents, the structure may change. In case of strong oxidants, amino groups and other groups may be oxidized, resulting in changes in structure and properties; in strong acid and alkali environments, reactions such as amino protonation or ring opening of benzothiazole rings may occur, affecting their stability.
Spectral properties: In the infrared spectrum, amino groups (-NH2O) exhibit characteristic absorption peaks at 3300-3500 cm , which are derived from the stretching vibration of N-H bonds; the skeleton vibration of the benzene ring has absorption peaks between 1450-1600 cm ; the benzothiazole ring also has specific absorption peaks, providing a basis for structural identification. In hydrogen nuclear magnetic resonance spectroscopy (HNMR), hydrogen atoms in different chemical environments exhibit corresponding chemical shifts. By analyzing the position of the peak, the integrated area and the coupling constant, the connection mode of hydrogen atoms in the molecule and the chemical environment can be clarified, and the structure can be accurately analyzed.
What is the price range of 2- (4-aminophenyl) -5-aminobenzimidazole in the market?
Today I have a question, what is the price range of 2- (4-aminopyridine) -5-aminopyridine-indole in the market. These are all chemical substances, and the determination of their price depends on many factors.
The source of the material, if the raw material is easy to harvest and not difficult to obtain, the price may be slightly cheaper; if the source is thin, it is not easy to obtain, and the price must be high.
It also depends on the preparation method. If the method is simple and efficient, it will save labor and speed, and the price may be low. If the method is complicated and dangerous, it will take a long time and cost a lot, and the price will be high.
Furthermore, the demand of the market is also the main reason. If there are many applicants, the goods are scarce, and the price will rise; if there are few applicants, the goods will be accumulated, and the price will be reduced.
However, I have searched all kinds of ancient books, but I have not obtained the exact price of these two things. The price of chemicals in the market today often varies according to time, place and situation.
Generally speaking, the price of these fine chemicals may vary depending on the purity. Low purity, per gram or tens of dollars; high purity, per gram or to hundreds of dollars, or even more than a thousand gold. If you buy in bulk, merchants may have discounts, and the total price will be different. If you really want to know the exact price, you should consult the merchants in the chemical market, the sellers of chemical materials, or visit the professional chemical trading platform to get the current real price.
What are the application fields of 2- (4-aminophenyl) -5-aminobenzimidazole
2-%284-%E6%B0%A8%E5%9F%BA%E8%8B%AF%E5%9F%BA%29-5-%E6%B0%A8%E5%9F%BA%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91, this is a chemically synthesized substance with a wide range of application fields.
In the field of medicine, this substance can be used as a drug intermediate. Gein 2-%284-%E6%B0%A8%E5%9F%BA%E8%8B%AF%E5%9F%BA%29-5-%E6%B0%A8%E5%9F%BA%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91 has a specific chemical structure and activity, and after ingenious chemical modification and transformation, it can become a drug molecule with a specific pharmacological activity. For example, in the development of some anti-infective drugs, based on this, after subsequent reactions, it can construct an active ingredient that can precisely act on pathogens, inhibit their growth and reproduction, and bring good news to the recovery of patients.
In the field of materials science, it also has important uses. It can participate in the synthesis of polymer materials, giving materials unique properties by means of copolymerization with other monomers. For example, introducing it into a polymer system can change the mechanical properties, thermal stability or optical properties of the material. If used in the preparation of high-performance engineering plastics, it can improve the strength and heat resistance of plastics, so that it can be applied in aerospace, automobile manufacturing and other fields that require strict material properties, to produce more durable and adapt to extreme environments.
In the agricultural field, 2-%284-%E6%B0%A8%E5%9F%BA%E8%8B%AF%E5%9F%BA%29-5-%E6%B0%A8%E5%9F%BA%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91 or can be used to synthesize new pesticides. With its chemical properties, pesticides with high selectivity, high efficiency and low toxicity to pests can be designed, which can effectively control crop diseases and pests, ensure food yield and quality, and reduce environmental pollution and impact on non-target organisms, contributing to sustainable agricultural development.