2 3 Phenylpropyl 1h Benzimidazole
quinoline thiophene imidazole thiazole

2-(3-phenylpropyl)-1H-benzimidazole

    Specifications

    HS Code

    915450

    Chemical Formula C16H16N2
    Molar Mass 236.31 g/mol
    Appearance Solid (usually white or off - white powder)
    Melting Point Specific value would need experimental determination
    Boiling Point Specific value would need experimental determination
    Solubility In Water Low solubility, likely sparingly soluble
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Pka Specific value would need experimental determination
    Density Specific value would need experimental determination
    Stability Stable under normal conditions, but may react with strong oxidizing or reducing agents

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    Frequently Asked Questions

    As a leading 2-(3-phenylpropyl)-1H-benzimidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 2- (3-phenylpropyl) -1H-benzimidazole?
    2-%283-%E8%8B%AF%E5%9F%BA%E4%B8%99%E5%9F%BA%29-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91, this compound has important uses in many fields.
    In the field of medicine, it is often a key intermediate. In the development of many drugs, complex active molecular structures are constructed based on specific chemical reactions. Because of its unique chemical properties and structural characteristics, it can precisely regulate the interaction between drugs and biological targets, enhance drug efficacy, and reduce adverse reactions. For example, in the process of antidepressant drug development, it is used as a starting material to synthesize compounds with high affinity for neurotransmitter receptors through multi-step reactions, thereby regulating neurotransmitter transmission and improving depression symptoms.
    In the field of materials science, it also shows unique value. Can participate in the preparation of materials with special optoelectronic properties. Introducing it into a polymer gives the material unique optical and electrical properties. For example, in the preparation of organic Light Emitting Diode (OLED) materials, this compound can optimize the luminous efficiency and stability of the material, make the OLED display show more brilliant colors and higher resolution, and help display technology innovation.
    At the level of scientific research and exploration, as an important research object of organic synthetic chemistry, scientists have deeply studied its reaction mechanism, developed novel synthesis methods and strategies, and promoted the development of organic synthetic chemistry. Its structural modification and derivatization research provides the possibility to discover new chemical substances and properties, expand the boundaries of chemical knowledge, and lay the foundation for innovative applications in more fields.
    What are the physical properties of 2- (3-phenylpropyl) -1H-benzimidazole?
    2-%283-%E8%8B%AF%E5%9F%BA%E4%B8%99%E5%9F%BA%29-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91, this is an organic compound. Its physical properties are unique, let me come one by one.
    Looking at its appearance, under normal conditions, it may be a colorless to light yellow liquid, clear and translucent, like morning dew, pure and free of impurities. Its texture is light, and under the sun, it shines softly.
    Smell its smell, emit a smell, or have a fragrant smell, but it is not a pungent and strong fragrance, just like the flowers of spring, fragrant and elegant, giving people a sense of pleasure, but not too much publicity.
    As for the boiling point, due to the molecular structure and interaction forces, the boiling point is in a specific range. Under appropriate pressure conditions, when it reaches a certain temperature, it will gradually change from liquid to gaseous state, and this temperature is its boiling point. This property is crucial in the process of separation and purification.
    In terms of melting point, when the temperature drops to a certain extent, the substance will solidify from liquid to solid. The level of melting point reflects the tightness of the molecular arrangement and the strength of the interaction. Like a soldier array, when it is tightly ordered, it needs a lower temperature to maintain the stability of the solid state.
    Solubility is also an important physical property. In organic solvents, such as ethanol, ether, etc., its solubility is good, just like fish entering water and can melt with it. However, in water, solubility or poor, due to the difference between molecular polarity and water molecules, it is difficult to disperse uniformly in water.
    The density is lighter than that of water, just like a feather floating on the water surface, when placed in water, it will float lightly on the upper layer, showing unique floating and sinking characteristics.
    The above are 2-%283-%E8%8B%AF%E5%9F%BA%E4%B8%99%E5%9F%BA%29-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91 common physical properties, which are of great significance for its research and application.
    What is the synthesis method of 2- (3-phenylpropyl) -1H-benzimidazole?
    2-%283-%E8%8B%AF%E5%9F%BA%E4%B8%99%E5%9F%BA%29-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91 that is, 2- (3 -indolyl) -1H -indolo-pyrrole, and its synthesis method is as follows:
    The starting material can be selected from suitable aniline derivatives and corresponding carbonyl-containing compounds. First, the aniline derivative is condensed with an aldehyde or ketone compound in the presence of an appropriate acidic or basic catalyst. This step requires precise control of the reaction temperature and time. If the temperature is too high or the time is too long, it is easy to cause side reactions to occur, affecting the purity and yield of the product; if the temperature is too low or the time is too short, the reaction is incomplete.
    Next, the generated intermediate product undergoes a dehydration cyclization reaction under the action of a specific dehydrating agent, forming a key indolo-pyrrole skeleton. In this step, the choice and dosage of the dehydrating agent are crucial. The activity and selectivity of different dehydrating agents vary, and careful choices must be made according to the characteristics of the reaction substrate and the requirements of the target product. At the same time, factors such as the solvent properties of the reaction system and the pH of the reaction environment will also have a significant impact on the cyclization process and results.
    Subsequent, functional group modification of the cyclization product may be required to introduce a 2- (3-indolyl) structure. This modification process is usually achieved by coupling reactions involving organometallic reagents, such as palladium-catalyzed cross-coupling reactions. During the reaction, the reaction conditions, including reaction temperature, reaction time, catalyst dosage, and ligand selection, must be strictly controlled to ensure that the reaction proceeds efficiently and selectively.
    The entire synthesis process is like a delicate dance of chemistry, and each step of the reaction requires careful regulation of various reaction parameters to successfully prepare 2- (3-indolyl) -1H-indolopyrrole, which provides a key compound basis for research and application in related fields.
    In which fields is 2- (3-phenylpropyl) -1H-benzimidazole used?
    2-%283-%E8%8B%AF%E5%9F%BA%E4%B8%99%E5%9F%BA%29-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91, its chemical name is 2- (3-indolyl) -1H-indole, which has extraordinary applications in medicine, materials science and many other fields.
    In the field of medicine, it shows significant biological activity. Studies have shown that this substance has inhibitory effect on some tumor cells. It can interfere with the proliferation and differentiation process of tumor cells through specific mechanisms, thus providing new ideas and potential directions for the research and development of anti-tumor drugs. In addition, in the study of neurological diseases, 2- (3-indolyl) -1H-indole has also been involved, which may provide assistance for the treatment of some neurodegenerative diseases.
    In the field of materials science, 2- (3-indolyl) -1H-indole has good optical and electrical properties due to its unique molecular structure. Scientists have used its properties to develop new organic optoelectronic materials. For example, its application in the manufacture of organic Light Emitting Diodes (OLEDs) is expected to improve the luminous efficiency and stability of OLEDs, and contribute to the progress of display technology. In the field of solar cells, this compound also shows potential application value, which may optimize the photoelectric conversion efficiency of batteries and promote the development of renewable energy technologies.
    In summary, 2- (3-indolyl) -1H-indole has become an important object of continuous exploration and research by researchers due to its diverse applications in the fields of medicine and materials science, and is expected to generate more innovative results in the future for the benefit of human society.
    What are the chemical properties of 2- (3-phenylpropyl) -1H-benzimidazole?
    The chemical properties of 2 - (3 -benzylpyridine) -1H -benzimidazole are quite unique, and allow me to describe them in detail for you.
    In this compound, the benzimidazole ring has certain aromatic properties and stability. Its nitrogen atom is rich in lone pairs of electrons, so it exhibits a certain alkalinity and can react with acids to form corresponding salts. This property is of great significance in many fields of organic reactions and pharmaceutical chemistry, or can be used to regulate the solubility and stability of compounds. The
    benzylpyridine part introduces special chemical activity to the compound. The benzyl ring and the pyridine ring in the benzyl group are fused in the conjugated system, which greatly affects the distribution of molecular electron clouds. The nitrogen atom of the pyridine ring makes this part alkaline, and can also participate in coordination chemistry-related reactions to form complexes with metal ions, which may be useful in the field of materials science and catalysis.
    Furthermore, this compound may have certain nucleophilic and electrophilic properties. Due to the difference in the distribution of electron clouds in the structure, carbon atoms or nitrogen atoms at specific locations can be used as nucleophilic check points to attack electrophilic reagents under suitable reaction conditions. On the contrary, some electron-deficient regions can also become electrophilic sites and accept nucleophilic reagent attacks.
    In addition, the solubility of this compound is also worthy of attention. Due to the presence of hydrophobic parts such as aromatic rings and nitrogen-containing heterocycles in the molecule, as well as possible polar groups, its solubility in organic solvents and water may exhibit special rules, or it has good solubility in some organic solvents, but poor solubility in water. This characteristic is a key consideration in the separation, purification and preparation of compounds.
    In summary, the chemical properties of 2- (3-benzylpyridine) -1H-benzimidazole are rich and diverse, and there are potential applications in many fields such as organic synthesis, drug research and development, and materials science.