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What is the chemical structure of 2- [[[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl] sulfonyl] -1H-benzimidazole
The structure of this compound can be obtained by its naming and disassembly. "2 - [ [ [ 3-methyl-4- (2,2,2-trichloroethoxy) phenyl] methyl] benzyl] -1H-indole", where 1H-indole is the core parent nucleus of this compound.
Prospective 1H-indole, which has a nitrogen-containing bilicyclic structure, one is a benzene ring and the other is a pyrrole ring, which is fused together. At position 2 of the indole ring, a complex side chain is connected. < Br >
The side chain starts with a benzyl structure. On the benzyl ring of this benzyl group, there is a methyl substitution at position 3, and a "4- (2,2,2-trichloroethoxy) " structure at position 4. In this structure, 2,2,2-trichloroethyl is connected to the benzyl ring with an oxygen atom.
In addition, the benzyl group connected to position 2, its methylene is then connected to another benzyl group to form a structure of "[[3-methyl-4- (2,2,2-trichloroethoxy) phenyl] methyl] benzyl".
In this way, the parts are connected according to the naming convention, that is, the chemical structure of "2 - [ [ [ 3-methyl-4- (2,2,2-trichloroethoxy) phenyl] methyl] benzyl] -1H-indole" is obtained. The determination of this structure is based on the law corresponding to the naming and structure of organic chemistry, and is formed by analyzing and connecting each group one by one.
What are the physical properties of 2- [[[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl] sulfonyl] -1H-benzimidazole
This is a question about the physical properties of 2 - [ [ [ 3 -methyl-4- (2,2,2 -trifluoroethoxy) phenyl] methyl] pyridyl] -1H -indole. This product is in a solid state at room temperature or in a solid state. Looking at its molecular structure, it contains aromatic rings and heterocycles. This structure often causes intermolecular forces to increase, so it is in a solid state. Its melting point varies depending on the specific crystal type and purity, but it can be accurately determined by a melting point meter.
In terms of solubility, in view of its hydrophobic aromatic ring and alkyl group, its solubility in water is extremely low. However, in organic solvents, such as dichloromethane, chloroform, toluene and other organic solvents, there may be a certain solubility, because its structure is similar to that of organic solvents.
Density is also an important physical property, and its density is related to the molecular weight and the degree of molecular packing. It can be determined by density measuring instrument according to relevant standard methods. Because its molecular structure contains fluorine atoms, the relative mass of fluorine atoms is relatively large, or its density is higher than that of ordinary hydrocarbon compounds.
The refractive index of this substance is related to the molecular polarizability and molecular arrangement. It can be determined by refractive spectrometer at a specific temperature and wavelength. Its refractive index value may vary depending on the solvent environment and sample purity.
In summary, the physical properties of 2 - [ [ [ 3 -methyl-4- (2,2,2 -trifluoroethoxy) phenyl] methyl] pyridyl] -1H -indole are significantly affected by molecular structure, and may vary under different conditions. When experimental measurement, pay attention to condition control.
What is the synthesis method of 2- [[[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl] sulfonyl] -1H-benzimidazole
To prepare 2 - [[[3-methyl-4- (2,2,2-trifluoroethoxy) phenyl] methyl] benzyl] -1H-indole, the following ancient method can be carried out.
First take an appropriate reaction vessel, wash and dry it. Using 3-methyl-4- (2,2,2-trifluoroethoxy) benzaldehyde as the starting material, with an appropriate active hydrogen-containing reagent, in the presence of a basic catalyst, according to the method of condensation reaction, the two condensation occurs, and an intermediate containing an ethylene bond can be obtained. In this step, the temperature should be controlled within a certain range, and the pH of the reaction system should be paid attention to to to ensure the smooth reaction.
After the obtained intermediate is prepared, the nucleophilic substitution reaction is carried out with benzyl halide in the presence of a phase transfer catalyst and an appropriate organic solvent. During the reaction, attention should be paid to the stirring rate to make the reactants fully contact and improve the reaction efficiency. After
, the above-mentioned obtained product is subjected to intracolecular cyclization reaction under the action of a suitable catalyst. The key to this step is to select a suitable catalyst and reaction temperature to form the basic structure of 1H-indole.
After the cyclization reaction is completed, the product is purified. The method of recrystallization can be used to select a suitable solvent, so that the product can be precipitated from the solution, and then filtered, washed, dried, etc., to obtain pure 2- [[3-methyl-4- (2,2,2 -trifluoroethoxy) phenyl] methyl] benzyl] -1H -indole. Pay attention to the specifications of each step of the reaction, and carefully monitor the reaction process to obtain the ideal yield and purity.
2- [[[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl] sulfonyl] -1H-benzimidazole What are the application fields
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In the field of chemical synthesis, this compound can be used as a specific anti-molecular agent. In chemical synthesis, due to its special properties, it can be used to build more complex molecules, such as in the construction of natural compounds or molecular skeletons with specific biological activities. Through careful anti-chemical methods, it can be used to introduce specific functionalities, and to obtain compounds of desired purpose.
In the field of chemical research, or because of its specific characteristics, it can be used as an active ingredient in biological agents. It may affect the physiological functions of biological agents or enzyme interactions. For example, the cellular pathway may provide new strategies for the treatment of certain diseases. For example, it may act as an active molecule that inhibits the cellular pathway of a specific tumor, and represents a new direction in the research of anti-cancer compounds.
In the field of materials science, this compound or its specialization can be used to synthesize materials with special properties. For example, through the copolymerization or combination of other substances, the material can have better mechanical properties, optical properties, etc. For example, in optical materials, it may affect the light absorption, light absorption and other properties of the material, and be used in the fabrication of photonic devices.
What is the market outlook for 2- [[[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl] sulfonyl] -1H-benzimidazole?
Today, there are 2 - [[[3-methyl-4 - (2,2,2-trichloroethoxy) phenyl] methyl] benzyl] -1H-indole, and its market prospects are related to many factors.
If it is used in the field of medicine, it can be used as an active ingredient and has therapeutic effect on specific diseases. If it can be confirmed by rigorous clinical trials that the curative effect and safety are good, the market demand is expected to surge. The pharmaceutical market is vast, and many diseases urgently need effective drugs. If this compound can emerge, it will attract the attention of pharmaceutical companies. Investment in research and development, production and sales, and the future may be bright.
In the field of materials, if it has unique physical and chemical properties, such as excellent optical and electrical properties, it can be used for the creation of new materials. With the rapid development of science and technology, the demand for high-performance materials is increasing. If it can meet the needs of electronics, optical materials and other industries, the application scenarios will continue to expand, and the market share will gradually increase.
However, there are also challenges. If the synthesis process is complex, cumbersome and costly, it must limit large-scale production, affecting market supply and price competitiveness. And regulations and regulations are increasingly stringent. Whether it is approval for medical use or safety standards for material applications, strict requirements must be met. If the standards are not met, the road to market entry will be full of thorns.
Furthermore, the market competition is quite fierce. Similar or alternative compounds may have occupied part of the market, and to stand out, they need to have unique advantages in performance, cost, environmental protection, etc.
To sum up, the market prospect of 2- [[3-methyl-4- (2,2,2-trichloroethoxy) phenyl] methyl] benzyl] -1H-indole has both opportunities and challenges. When all conditions are met, a wide range of fields may be developed.