2 3 Methyl 4 2 2 2 Trifluoroethoxy Pyridin 2 Yl Methyl Sulfinyl 1h Benzimidazole
quinoline thiophene imidazole thiazole

2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole

    Specifications

    HS Code

    511908

    Chemical Formula C20H17F3N4O3S
    Molecular Weight 452.43
    Appearance Typically a solid
    Melting Point Specific value would require literature search
    Boiling Point Specific value would require literature search
    Solubility Solubility characteristics depend on solvent; data would need to be sourced
    Pka Value would need to be determined experimentally or from literature
    Logp Data would need to be obtained from relevant sources
    Chemical Stability Stability under different conditions (e.g., temperature, pH) needs to be investigated
    Crystal Structure Determined by X - ray crystallography; data would need to be sourced
    Vapor Pressure Value would require experimental determination or literature search

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    General Information
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    Frequently Asked Questions

    As a leading 2-({[3-methyl-4-(2,2,2-trifluoroethoxy)pyridin-2-yl]methyl}sulfinyl)-1H-benzimidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 2- ({[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl} sulfinyl) -1H-benzimidazole?
    This is a chemical nomenclature. To know its chemical structure, it is necessary to analyze it with chemical knowledge. "2 - {[3-methyl-4 - (2,2,2-trifluoroethoxy) pyridine-2-yl] methyl} sulfinyl-1H-benzimidazole", its core structure is benzimidazole, which is connected with a complex substituent at the second position of 1H-benzimidazole. This substituent is composed of sulfinyl-linked {[3-methyl-4 - (2,2,2-trifluoroethoxy) pyridine-2-yl] methyl}. The third position of the pyridine ring has a methyl group, and the fourth position is connected to a 2,2,2-trifluoroethoxy group. In the structure of this compound, benzimidazole is a fused double ring structure, which is formed by fusing a benzene ring and an imidazole ring. The pyridine ring is a six-membered nitrogen-containing heterocycle with a specific substituent distribution. The sulfinyl group is S = O structure, which connects different groups, giving it unique chemical properties. In summary, the chemical structure of this compound is composed of benzimidazole, pyridine and other structural units through a specific connection method, and the interaction of each part gives it specific chemical activities and properties.
    What are the physical properties of 2- ({[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl} sulfinyl) -1H-benzimidazole?
    2-% 28 +% 7B% 5B3 - methyl - 4 -% 282% 2C2% 2C2 - trifluoroethoxy%29pyridin - 2 - yl%5Dmethyl%7Dsulfinyl%29 - 1H - benzimidazole, this is an organic compound with unique physical properties.
    It is usually solid at room temperature and pressure. The melting point of this compound is one of its important physical properties. The exact value of the melting point depends on the strength of intermolecular forces, such as hydrogen bonds, van der Waals forces, etc. The arrangement and interaction of atoms in the molecular structure together determine the melting point. After experimental determination, the precise melting point value can be obtained, which is of great significance for the identification and purification of this compound.
    Solubility is also a key physical property. Its solubility in organic solvents varies depending on the type of solvent. In polar organic solvents, such as ethanol and acetone, it may exhibit a certain solubility due to the interaction between molecular polarity and solvent polarity. In non-polar solvents, solubility or poor. The characteristics of solubility have a significant impact on the reaction and separation process of compounds in solution.
    The density of the compound is also a characterization of physical properties. Density reflects the mass of a substance per unit volume and is related to the degree of close packing of molecules. Through accurate experimental measurement, its density data can be obtained, which provides an important reference in chemical production and the determination of the mixing ratio of substances.
    In addition, its appearance may have a specific color and shape. It may be white or off-white powder, which makes it easy to initially identify and distinguish from other compounds.
    The physical properties of this compound are determined by its unique molecular structure, and the properties are interrelated, which plays a crucial role in its application in chemistry, medicine and other fields.
    What are the main uses of 2- ({[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl} sulfinyl) -1H-benzimidazole?
    2-% 28 +% 7B% 5B3 - methyl - 4 -% 282% 2C2% 2C2 - trifluoroethoxy%29pyridin - 2 - yl%5Dmethyl%7Dsulfinyl%29 - 1H - benzimidazole, an organic compound, often referred to in chemical terms, commonly known as rabeprazole sodium, is a benzimidazole compound. Its main use is quite extensive, in the field of medicine, often used as proton pump inhibitors.
    Looking at the human stomach, the cells of the stomach wall secrete gastric acid, which is crucial for food digestion. However, excessive stomach acid can cause various stomach discomfort symptoms, such as gastric ulcer, duodenal ulcer, reflux esophagitis, etc. Rabeprazole sodium, like the guardian of the stomach, can precisely act on the proton pump on the cells of the stomach wall. Proton pump, like a key gate in the process of gastric acid secretion, Rabeprazole sodium can effectively inhibit the opening of this gate, thereby significantly reducing the amount of gastric acid secretion. In this way, it can relieve many diseases caused by excessive gastric acid for patients and help the stomach recover.
    Therefore, 2-% 28 +% 7B% 5B3-methyl-4 -% 282% 2C2% 2C2-trifluoroethoxy%29pyridin-2-yl%5Dmethyl%7Dsulfinyl%29-1H-benzimidazole is mainly used to treat gastric acid-related gastric diseases, and is an important agent in the field of medicine to protect stomach health.
    What are the synthesis methods of 2- ({[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl} sulfinyl) -1H-benzimidazole?
    To prepare 2 - {[3-methyl-4- (2,2,2-trifluoroethoxy) pyridine-2-yl] methyl} sulfinyl-1H-benzimidazole, the synthesis method has been studied by chemists throughout the ages, and there are many wonderful methods handed down.
    One method is to use 2-chloromethyl-3-methyl-4- (2,2,2-trifluoroethoxy) pyridine as the starting material. First, it undergoes a nucleophilic substitution reaction with thiol salts. This step requires a suitable solvent, such as dimethylformamide, and the temperature needs to be controlled in a moderate range, about 50-70 degrees Celsius, to promote the full reaction of the two and generate the corresponding thioether intermediates. Subsequently, the intermediate is oxidized, and an isothermal oxidizing agent of hydrogen peroxide or m-chloroperoxybenzoic acid can be selected. Under appropriate reaction conditions, the thioether is converted into the target sulfoxide product, namely 2 - {[3-methyl-4- (2,2,2-trifluoroethoxy) pyridine-2-yl] methyl} sulfinyl-1H-benzimidazole.
    Another method is to use 2-methyl-3-nitro-4- (2,2,2-trifluoroethoxy) pyridine as the starting material. The nitro group is first reduced to an amino group, and the commonly used reducing agent such as iron/hydrochloric acid system or hydrogen/palladium carbon catalyst converts the nitro group into an active amino group. Then, the product containing the amino group is condensed with o-phenylenediamine in the presence of a suitable acidic catalyst to form a benzimidazole ring. Finally, through specific thioetherification and oxidation steps, as in the previous method, the target product is obtained.
    Another one uses 2-halo benzimidazole as the starting material. First, it undergoes nucleophilic substitution reaction with halogenated hydrocarbons containing 3-methyl-4- (2,2,2-trifluoroethoxy) pyridine structure to form carbon-sulfur bonds to obtain thioether intermediates. After that, it is oxidized to obtain the target sulfinyl group product.
    Each of these synthesis methods has its own strengths. Chemists can choose the best one according to the availability of raw materials, the difficulty of reaction, and cost considerations, so as to achieve the efficient synthesis of 2 - {[3-methyl-4- (2,2,2-trifluoroethoxy) pyridine-2-yl] methyl} sulfinyl-1H-benzimidazole.
    What is the market outlook for 2- ({[3-methyl-4- (2,2,2-trifluoroethoxy) pyridin-2-yl] methyl} sulfinyl) -1H-benzimidazole?
    2-%28+%7B%5B3-methyl-4-%282%2C2%2C2-trifluoroethoxy%29pyridin-2-yl%5Dmethyl%7Dsulfinyl%29-1H-benzimidazole, this is a specific organic compound. Looking at its market prospects, there is a strong demand for compounds with unique structures and characteristics in the field of pharmaceutical research and development today. This compound may emerge in the study of drug activity due to its own structure.
    From the perspective of innovation, chemical synthesis technology is constantly improving, and researchers are committed to creating novel and efficient synthesis paths to improve the yield and purity of such compounds. If a cost-effective synthesis method can be found, it will greatly promote it to the market.
    Furthermore, drug development needs to go through a long and rigorous process. If this compound exhibits potential pharmacological activity, a series of studies on pharmacology, toxicology, etc. need to be carried out in depth. Once it passes the rigorous evaluation, it may become a new drug for the treatment of specific diseases, injecting vitality into the pharmaceutical market.
    However, there are also challenges. First, the synthesis process may be complex and expensive, limiting large-scale production. Second, under the fierce market competition, it is necessary to quickly seize the opportunity and stand out.
    Overall, 2-%28+%7B%5B3-methyl-4-%282%2C2%2C2-trifluoroethoxy%29pyridin-2-yl%5Dmethyl%7Dsulfinyl%29-1H-benzimidazole market prospects are full of opportunities and challenges. With scientific research progress and reasonable planning, it is expected to shine in the pharmaceutical market.