2 3 Bromophenyl 1 Phenyl 1h Benzimidazole
quinoline thiophene imidazole thiazole

2-(3-bromophenyl)-1-phenyl-1H-benzimidazole

    Specifications

    HS Code

    588204

    Chemical Formula C20H13BrN2
    Molecular Weight 361.24
    Appearance Solid (predicted)
    Solubility In Water Low solubility (predicted)
    Solubility In Organic Solvents Soluble in common organic solvents (predicted)
    Logp Predicted to be lipophilic

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    Frequently Asked Questions

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    What are the physical properties of 2- (3-bromophenyl) -1-phenyl-1H-benzimidazole
    2-%283-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1-%E8%8B%AF%E5%9F%BA-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91%E7%9A%84%E5%88%99%E4%B8%BA2 - (3 - x) - 1 - x - 1H - x + y (here\ (x\) instead of benzene,\ (y\) instead of pyridine, convenient expression), simplification can be obtained:\ (2 - 3 + x - 1 - x - 1H - x + y = -2 - 1H - x + y\). This substance is an organic compound, and its physical properties are as follows:
    Looking at its properties, under normal temperature and pressure, it is mostly in a liquid state, with a clear texture, resembling colorless water, but it also has a unique appearance. Under light, there are occasional glimmers of light, as if concealing mysterious breath.
    Smell its smell, with a special fragrance, not vulgar fragrance, but like the fragrance of ancient books, leisurely, but clearly discernible, lingering on the tip of the nose, giving people a unique impact of smell.
    In terms of its solubility, in organic solvents such as ethanol and ether, it is like a fish entering water, which can be well miscible and blend seamlessly; however, in the water environment, it is like the barrier between oil and water, which is difficult to blend, and is mostly in a layered state.
    Looking at its boiling point, due to the force between molecules, the boiling point is quite high, and a higher temperature is required to make it change from liquid to gaseous state, just like it has been tested many times before it can be sublimated.
    Depending on its density, it is slightly lighter than water. If it is placed in one place with water, it can be seen that it floats lightly on the water surface, like a boat on water, leisurely.
    The physical properties of this compound are of great significance in many fields such as organic synthesis and chemical research, paving the way for scientific research and exploration.
    What are the chemical properties of 2- (3-bromophenyl) -1-phenyl-1H-benzimidazole
    2-%283-%E6%BA%B4%E8%8B%AF%E5%9F%BA%29-1-%E8%8B%AF%E5%9F%BA-1H-%E8%8B%AF%E5%B9%B6%E5%92%AA%E5%94%91, this is the expression of a chemical substance, and its chemical properties should be understood in ancient French.
    This substance contains specific groups and structures, and its chemical properties are unique. From the perspective of reactivity, due to the specific benzene ring structure and related substituents, it exhibits certain activity in the electrophilic substitution reaction. The electron cloud density distribution of the benzene ring is affected by the substituent group, making the benzene ring more vulnerable to the attack of electrophilic reagents.
    In the oxidation reaction, because there are parts that can be oxidized in the structure, under suitable oxidizing agents and reaction conditions, oxidation changes can occur. For example, in case of strong oxidizing agents, the oxidation of the substituent group or the partial change of the benzene ring structure may be caused. < Br >
    In terms of reduction reactions, specific functional groups can undergo reduction reactions under the action of suitable reducing agents, such as some unsaturated bonds can be reduced to saturated bonds, thereby changing the structure and properties of the substance.
    In an acid-base environment, its chemical properties are also different. If it is in an acidic environment, some functional groups may protonate, changing their electron cloud distribution and reactivity; in an alkaline environment, reactions such as substitution and elimination may occur, depending on their specific structure and the strength of alkalinity.
    Furthermore, its physical properties and chemical properties are interrelated. Such as solubility, due to the existence of polar and non-polar parts of the molecular structure, the solubility varies in different solvents, and this property also affects its behavior in chemical reactions. Its chemical properties are complex and changeable, and it is affected by the interaction of various parts in the structure. Under different reaction conditions, it presents a variety of reaction results.
    What are the synthesis methods of 2- (3-bromophenyl) -1-phenyl-1H-benzimidazole
    To prepare 2 - (3 - thiophenyl) - 1 - thiophenyl - 1H - thiophenopyrazole, there are many synthesis methods, and each has its advantages and disadvantages, which are described in detail below.
    First, thiophene derivatives are used as starting materials to construct the target structure through multi-step reactions. First, take an appropriate thiophene derivative, and under specific conditions, make a substitution reaction at a specific position on the thiophene ring, and introduce the desired substituent. This substitution reaction requires fine regulation of reaction conditions, such as temperature, catalyst dosage, etc., so that the reaction can be selectively carried out to obtain key intermediates. Then, the intermediate is reacted with another nitrogen-containing heterocyclic compound in a suitable base and solvent system, and through the cyclization step, the parent nuclear structure of thiophene and pyrazole is constructed. In this process, the cyclization conditions are also extremely important, which will affect the yield and purity of the product.
    Second, the strategy of transition metal catalysis is adopted. Using thiophene-containing halogenates or borate esters as substrates, under the action of transition metal catalysts (such as palladium, copper, etc.), the coupling reaction occurs with the nucleophile of the nitrogen-containing heterocyclic ring. The advantage of this method is that the reaction conditions are relatively mild and the carbon-heteroatom bond can be effectively constructed. However, transition metal catalysts are expensive, and post-reaction treatment needs to pay attention to the residual problem of the catalyst, so as not to affect the quality of the product.
    Third, with the help of intramolecular cyclization reaction. First, design and synthesize a linear precursor molecule with a suitable functional group, which needs to contain thiophenyl and potential cyclization check points. Subsequently, under the action of heat, light or chemical reagents, an intramolecular cyclization reaction occurs to generate the target 2 - (3 - thiophenyl) -1 - thiophenyl - 1H - thiophenopyrazole. This method has high atomic economy and relatively simple steps. However, the synthesis of precursor molecules also requires certain skills and conditions optimization.
    All synthetic methods have their own strengths and weaknesses. In practical application, it is necessary to comprehensively consider the availability of raw materials, cost, difficulty in controlling reaction conditions, and the purity and yield of the product, and make a prudent choice.
    In which fields is 2- (3-bromophenyl) -1-phenyl-1H-benzimidazole used?
    2- (3-cyanophenyl) -1-phenyl-1H-benzopyrazole compounds have applications in the fields of medicine, materials and agriculture, and are classified as follows.
    In the field of medicine, it exhibits quite significant biological activity. Many studies have shown that these compounds have potential anti-tumor activity. Through specific mechanisms, they can inhibit the proliferation of tumor cells and induce tumor cell apoptosis, opening up new paths for the development of anti-tumor drugs. For example, some derivatives can precisely act on key targets in tumor cells, blocking tumor cell growth signaling pathways, thereby inhibiting tumor growth. In addition, these compounds also have anti-inflammatory properties, which can regulate the release of inflammatory mediators in the body, reduce the inflammatory response, or can be developed as new anti-inflammatory drugs.
    In the field of materials, 2- (3-cyanophenyl) -1-phenyl-1H-benzopyrazole compounds can be used to prepare functional materials. Due to its unique molecular structure, it has specific optical and electrical properties. For example, it can be applied to organic Light Emitting Diode (OLED) materials. With its luminous properties, the luminous efficiency and color purity of OLED devices can be improved, which contributes to the development of display technology. Or it can be used to prepare sensor materials, and by virtue of its interaction with specific substances, it can achieve highly sensitive detection of certain substances.
    In the agricultural field, such compounds may have agricultural activities. On the one hand, it may be developed as a new type of pesticide, which has repellent or toxic effects on some crop pests, and may have lower environmental toxicity and higher selectivity than traditional pesticides, which is conducive to the development of green agriculture. On the other hand, it may have a regulatory effect on plant growth, which can promote plant growth and enhance plant resistance, such as improving plant resistance to drought, salinity and other stresses, thereby improving crop yield and quality.
    What is the market outlook for 2- (3-bromophenyl) -1-phenyl-1H-benzimidazole?
    In today's world, the market prospects of 2- (3-benzyl) -1-benzyl-1H-indolopyridine and the like are related to many parties.
    Guanfu such compounds are gradually emerging in the field of pharmaceutical research and development. Its unique structure may have the ability to specifically combine with biological targets, just like a delicate key that can open specific biological locks. Therefore, many pharmaceutical companies and scientific research institutes have cast their attention on it, hoping to use it to develop new agents to cure various diseases.
    If it is anti-cancer, this compound may be able to inhibit the proliferation and metastasis of cancer cells by regulating cell signaling pathways, just like building a strong barrier in the battlefield where cancer cells are raging. In the prevention and treatment of nervous system diseases, it may regulate the metabolism of neurotransmitters, improve nerve cell function, and bring hope to patients trapped in epilepsy, Parkinson's disease, etc.
    Furthermore, in the field of materials science, it may emerge due to its unique photoelectric properties. It can be used as a new type of luminescent material in Light Organic Emitting Diode (OLED) to make the display screen more gorgeous and lower energy consumption, as if injecting a new force into the display technology field.
    However, its market prospects are not smooth. The complexity of the synthesis process and the high cost are like a steep mountain, and there is a way forward. And the research and development of new drugs requires long and rigorous clinical trials, during which the risks are unpredictable. Material applications also need to overcome many difficulties such as stability and large-scale preparation.
    Although there are challenges, opportunities coexist. With the advancement of science and technology, the synthesis process may be simplified and costs can be controlled. If there is a breakthrough in clinical research and the advent of new drugs, it will definitely open up a broad market. If the application of materials can solve the problem, it will also set off a wave of innovation in related industries. Therefore, the market prospect of 2- (3-benzyl) -1-benzyl-1H-indolopyridine is full of variables and hope, and it is worth all parties to move forward and explore its endless possibilities.