2-[(2R)-2-Methylpyrrolidin-2-yl]-1H-benimidazole-4-carboxamide, dihydrochloride salt

2-%5B%282R%29-2-Methylpyrrolidin-2-yl%5D-1H-benimidazole-4-carboxamide, the expression of dihydrochloride salt is an organic compound. To clarify its chemical structure, consider its name.
"2 - [ (2R) - 2 - Methylpyrrolidin - 2 - yl]", showing that the benzimidazole ring is connected to the second position of a (2R) - 2 - methylpyrrolidin - 2 - group. Pyrrolidine is a nitrogen-containing five-membered heterocyclic ring with a methyl group at the second position and has an R configuration.
"1H - benimidazole - 4 - carboxamide", which is called 1H - benzimidazole - 4 - formamide, benzimidazole is formed by fusing the benzene ring with the imidazole ring, and the 4 position has a formamide group.
"dihydrochloride salt", which means that this compound forms a dihydrochloride salt, or can form a salt with hydrochloric acid due to the basic check point in the molecule.
Its chemical structure is roughly as follows: the central benzimidazole ring, the 2-position (2R) -2-methylpyrrolidine-2-group, the 4-position diformamide group, and the whole exists in the form of dihydrochloride salt. In this structure, the benzimidazole ring has a conjugated system, and the nitrogen atom of the pyrrolidine ring can participate in the reaction. The formamide group also has its specific chemical activity, and the dihydrochloride form affects its solubility and chemical properties.

2 - [ (2R) -2 -methylpyrrolidine-2-yl] -1H -benzimidazole-4 -formamide dihydrochloride has a wide range of uses. In the field of medicine, it is often a key intermediate for the development of new drugs. Pharmaceutical developers use its unique chemical structure to explore and create compounds with specific biological activities, which may be promising drugs for the treatment of difficult diseases.
In the field of chemical research, it also plays an important role. Chemists use it to conduct research on organic synthesis reactions, gain insight into reaction mechanisms, and explore novel synthetic pathways, in order to improve the efficiency and accuracy of organic synthesis. Because its structure contains specific functional groups, it can trigger a variety of chemical reactions, contributing to the development of organic synthetic chemistry.
In the field of life sciences, it may be used as a biological probe. With the interaction with biological macromolecules such as proteins and nucleic acids, scientists can analyze complex biochemical processes in living organisms, reveal the mysteries of life, and promote the progress of basic research in life sciences.
This compound has important uses in many fields such as medicine, chemistry, and life sciences. It is like a key, opening new doors for research in various fields, leading researchers to explore the unknown, pursue innovation, and make unremitting progress for human well-being and scientific progress.

To prepare 2 - [ (2R) -2 -methylpyrrolidine-2-yl] -1H -benzimidazole-4 -formamide dihydrochloride, you can follow the following method.
First take a suitable starting material, which contains structural fragments that can construct benzimidazole rings and pyrrolidine rings. Start with a compound with benzene ring and an amino group, react with a carbonyl-containing reagent under suitable conditions to construct a benzimidazole ring. This reaction may require acid or base catalysis, and heat to promote its cyclization.
When the benzimidazole ring is obtained, then introduce the pyrrolidine ring part. The pyrrolidine derivative with suitable substituents is connected to the benzimidazole intermediate through nucleophilic substitution or condensation reaction. During the reaction, appropriate solvents, such as dichloromethane, N, N-dimethylformamide, etc., are selected to facilitate the reaction.
After obtaining 2 - [ (2R) -2 - methylpyrrolidine - 2 - yl] -1H - benzimidazole - 4 - formamide, to prepare its dihydrochloride salt, the compound can be dissolved in an appropriate amount of organic solvents, such as ethyl ether, ethanol, etc., into dry hydrogen chloride gas. Hydrogen chloride forms a salt with the amino group in the compound, precipitates the dihydrochloride, and then filters, washes, and dries to obtain pure 2- [ (2R) -2 -methylpyrrolidine-2-yl] -1H -benzimidazole-4 -formamide dihydrochloride. After each step of the reaction, it needs to be detected by chromatography, spectroscopy, etc. to confirm the purity and structure of the product.

2 - [ (2R) -2 -methylpyrrolidine-2-yl] -1H -benzimidazole-4 -formamide dihydrochloride, which is complex and changeable in physical properties and has unique physical and chemical properties.
Looking at its physical properties, it often appears as a white crystalline powder at room temperature, which is fine and uniform. Its solubility is of great concern, and it is soluble in water. Due to the interaction between polar groups in the molecular structure and water molecules, it is like fish-water fusion, but it is poorly soluble in non-polar organic solvents.
When it comes to chemical properties, the benzimidazole ring in this compound has certain aromatic properties and stability, which is like a strong fortress and is difficult to be easily shaken. The methyl group on its pyrrolidine group, although small, affects the spatial structure of the molecule and the distribution of electron clouds, which in turn affects its chemical activity. The form of dihydrochloride allows the compound to dissociate hydrogen ions in solution, which is acidic and can neutralize with bases, just like yin and yang, generating corresponding salts and water. In addition, its amide group can participate in a variety of chemical reactions, such as hydrolysis. Under certain conditions, the amide bond is like a fragile bond, which is easily cut off to form carboxylic acids and amines. In this way, 2- [ (2R) -2 -methylpyrrolidine-2-yl] -1H -benzimidazole-4 -formamide dihydrochloride has unique and rich physical and chemical properties, and has potential application value in many fields.

In today's world, it is not easy to know the price of 2- [ (2R) -2 -methylpyrrolidine-2-yl] -1H -benzimidazole-4 -formamide dihydrochloride on the market. The price of these compounds, or involved in professional pharmaceutical and chemical fields, is affected by many factors.
First, the difficulty of production. If the synthesis method is complicated, rare reagents and harsh conditions are required, and the cost is high and the price is not cheap. Second, the difference between purity. High purity, because of the difficulty of refining, the price must be higher than that of low purity. Third, the supply and demand situation. If the demand is strong and the supply is limited, the price will rise; conversely, if the supply exceeds the demand, the price may fall.
If you want to know the price, you need to visit chemical raw material suppliers and pharmaceutical intermediates distributors. Or you can search and inquire on professional chemical trading platforms, such as Gade Chemical Network, Mobell, etc., to get a more accurate quotation. Or contact the relevant manufacturer to inquire directly, or you can get first-hand price information. However, the market price fluctuates constantly, and the real-time price is still subject to the current inquiry.