2 1 2 3 4 Tetrahydronaphthalen 1 Yl 4 5 Dihydro 1h Imidazole
quinoline thiophene imidazole thiazole

2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole

    Specifications

    HS Code

    796853

    Chemical Formula C15H18N2
    Molecular Weight 226.32 g/mol

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    General Information
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    Frequently Asked Questions

    As a leading 2-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4,5-dihydro-1H-imidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole?
    2-%281%2C2%2C3%2C4-%E5%9B%9B%E6%B0%A2%E8%90%98-1-%E5%9F%BA%29-4%2C5-%E4%BA%8C%E6%B0%A2-1H-%E5%92%AA%E5%94%91%E7%9A%84%E5%8C%96%E5%AD%A6%E6%80%A7%E8%B4%A8%E6%98%AF%E4%BB%80%E4%B9%88%3F this chemical substance is more complex and unconventional, and needs to be disassembled and analyzed.
    Structurally, the substance may have a specific atomic connection and functional group combination. 2 - (1,2,3,4-tetrahydronaphthalene-1-yl) This part indicates the existence of a tetrahydronaphthalene structure, and a substituent is connected at its No. 1 position. This structure imparts certain rigidity and aromatic properties to the substance. Due to its degree of hydrogenation, tetrahydronaphthalene partially has relatively higher saturation than naphthalene. In chemical reactions, its carbon-carbon double bond and the surrounding electron cloud distribution will affect the reactivity.
    4,5-dioxy-1H-pyrazole part, 1H-pyrazole ring itself has a certain conjugate system, and the dioxy substitution at 4,5 positions further changes the electron cloud density and reaction check point on the ring. The electronegativity of the oxygen atom is large, which will cause the electron cloud on the pyrazole ring to shift to the oxygen atom, making some positions on the ring more prone to electrophilic or nucleophilic reactions, depending on the reaction conditions.
    Overall, the substance has certain stability, but under suitable conditions, such as specific acid-base environment, temperature, light or the presence of catalysts, substitution reactions, redox reactions, etc. can occur. Due to the fact that its structure contains both aromatic hydrocarbons and nitrogen-containing heterocycles with oxygen substituents, it may have potential application value in the fields of organic synthesis, medicinal chemistry, etc. It can be used as an intermediate for the construction of more complex compounds, participating in various cyclization, functional group transformation and other reactions, resulting in products with different biological activities or physicochemical properties.
    What are the common synthesis methods of 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole?
    To prepare 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-pyrrole, the common synthesis methods are as follows:
    First, it can be prepared by multi-step reaction between aromatic hydrocarbons containing suitable substituents and unsaturated nitrogenous compounds. First, a specific aromatic hydrocarbon is used as the starting material and halogenated to introduce halogen atoms. In this step, suitable halogenating reagents and reaction conditions are selected. For example, liquid bromine is used for halogenation under the action of catalyst. The obtained halogenated aromatic hydrocarbons are then reacted with nitrogen-containing nucleophiles to construct nitrogen-containing structural units. During the reaction, attention should be paid to the activity of nucleophiles and the reaction environment. Subsequent steps such as reduction and cyclization are used to gradually construct the structure of the target product. Appropriate metal hydride reagents can be selected for the reduction step, and the cyclization step needs to adjust the reaction conditions to promote cyclization.
    Second, the cyclization reaction strategy is used. Select the precursor containing appropriate carbon chains and functional groups, and construct the target structure through intramolecular cyclization reaction. The precursor is converted and modified by functional groups to make the structure of each part suitable for cyclization. For example, the functional group is activated by esterification, amidation and other reactions, and then cyclization is initiated under acidic or basic catalytic conditions. During the process, the reaction temperature, time and catalyst dosage need to be precisely controlled to ensure the selectivity and yield of the cyclization reaction.
    Third, the transition metal catalytic synthesis path is used. With the unique catalytic properties of transition metal catalysts, it promotes the formation of carbon-carbon and carbon-nitrogen bonds. Transition metal catalysts such as palladium and nickel can catalyze the coupling reaction of halogenated hydrocarbons with alkenyl and alkynyl compounds. Halogenated aromatics and alkenyl amines are used as raw materials under the catalysis of transition metals, and then converted into target products through subsequent reactions. In this path, catalyst selection, ligand design and reaction system optimization are extremely critical, which are related to reaction activity and selectivity.
    In which fields is 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole used?
    2-%281%2C2%2C3%2C4-%E5%9B%9B%E6%B0%A2%E8%90%98-1-%E5%9F%BA%29-4%2C5-%E4%BA%8C%E6%B0%A2-1H-%E5%92%AA%E5%94%91 this chemical substance, it is useful in many fields such as medical, alchemy, and artifact forging.
    In the medical way, it can be used as medicine to treat diseases by virtue of its unique properties. Or it can regulate qi and blood, make the body's qi and blood smooth, and relieve many discomforts caused by poor qi and blood. For example, it can have a certain soothing effect on the pain caused by qi stagnation and blood stasis; in some deficiency caused by qi and blood deficiency, it can also play an auxiliary recuperation effect.
    In alchemy, this substance can be used as a key ingredient. Alchemists are well aware of its characteristics and add it when carefully preparing elixir prescriptions, hoping to use its effect to improve the quality and efficacy of elixirs. Or it can make the medicinal pill more effective in prolonging life and strengthening the body, and help the cultivator reach a higher level of practice.
    In the field of artifact forging, it can be used to temper special materials. Incorporated into a specific metal, it can change the characteristics of the metal, making the forged artifact more tough and sharp. When building a sword, adding it may make the sword body hard and tough, with an incomparably sharp edge, cutting iron like mud, and becoming a rare divine weapon in the world.
    What is the market outlook for 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole?
    There are currently 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-indole products, and their market prospects are as follows:
    This 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-indole has great potential in the field of medicine. Many studies have shown that its structure may interact with specific biological targets, and it is expected to be developed into new drugs. At present, the pharmaceutical industry has a growing demand for novel and targeted drugs. If we can deeply explore the pharmacological activity of this compound and develop drugs with good curative effect and small side effects, we will be able to occupy a place in the pharmaceutical market.
    In materials science, due to its unique chemical structure, it may endow materials with special properties. For example, in optical materials, it may affect the light absorption and emission characteristics of materials; in polymer materials, it may change the mechanical properties and stability of materials. With the continuous development of materials science, the demand for materials with special properties is increasing. If we can tap its application value in the field of materials, the market prospect is broad.
    However, its marketing activities also face challenges. First, the synthesis process of this compound may be complicated and expensive, which will limit its large-scale production and application. Secondly, the research on its properties and applications still needs to be in-depth, and a lot of time and money need to be invested in experiments and tests. Only by overcoming these difficulties, optimizing the synthesis process, reducing costs, and fully understanding its properties can we fully demonstrate the market potential of 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-indole and open up a broader market space.
    What are the precautions in the preparation of 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole?
    In the process of preparing 2- (1,2,3,4-tetralin-1-yl) -4,5-dihydro-1H-pyrazole, the following points should be paid attention to:
    In terms of starting materials, the purity of 1,2,3,4-tetralin-1-yl related raw materials is very important, and its impurities may affect the reaction path and product purity. If the raw material contains impurities, by-products may be formed in the reaction, interfering with the formation of the target product. If the raw material contains oxidizing impurities, under certain reaction conditions, oxidation side reactions may be initiated, resulting in changes in the structure of the product.
    In the reaction conditions, the temperature needs to be precisely controlled. Different reaction stages have strict temperature requirements, and improper heating or cooling rates may affect the reaction process. For example, if the initial temperature of the reaction is too high and the reaction rate is too fast, it is easy to generate too many by-products; if the temperature is too low, the reaction will be delayed or even stagnant. Take a specific organic reaction as an example, the temperature deviation is 5 ° C, and the product yield may fluctuate by 10% - 20%. The selection and dosage of
    catalysts cannot be ignored. Suitable catalysts can accelerate the reaction, improve the yield and selectivity. However, if the amount of catalyst is too much or too little, the effect is not good. If the dosage is too small, the catalytic efficiency is low, and the reaction is incomplete; if it is too much, it may lead to unnecessary side reactions, and increase the cost and subsequent separation difficulty.
    The reaction solvent has a significant impact on the reaction. The solvent not only provides a site for the reaction, but also affects the solubility and reactivity of The selected solvent should be able to dissolve the reactants and catalysts well without side reactions with them. If some aprotic solvents are conducive to nucleophilic substitution reactions, protonic solvents may inhibit such reactions.
    In the post-processing stage, product separation and purification are complicated and critical. Due to the complex reaction system, it contains unreacted raw materials, by-products and catalyst residues. Choosing an appropriate separation method, such as extraction, distillation, column chromatography, etc., is crucial to obtain high-purity products. During extraction, the extraction agent is not selected properly, and the target product and impurities cannot be effectively separated. In column chromatography, the ratio of fixed phase selection and eluent is wrong, or the product and impurities are difficult to separate.
    During the entire preparation process, the control of the details of each link is related to the quality and yield of the final product, requiring rigorous operation, careful observation and precise regulation by the experimenter.