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What is the chemical structure of 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole nitrate?
This is about the chemical structure of 2- (1,2,3,4-tetrahydroquinoline-1-yl) -4,5-dihydro-1H-pyrazole-3-carboxylic anhydride. Let me explain in detail.
In this compound, 2- (1,2,3,4-tetrahydroquinoline-1-yl) is indicated at position 2 of the main structure, and there is a group of 1,2,3,4-tetrahydroquinoline-1-yl. 1,2,3,4-tetrahydroquinoline is a partially hydrogenated product of the quinoline ring, and its nitrogen atom is numbered 1. This nitrogen atom is connected to the main structure.
Furthermore, 4,5-dihydro-1H-pyrazole-3-carboxylic anhydride means that the main structure is a 4,5-dihydro-1H-pyrazole ring, which is a five-membered heterocycle composed of two nitrogen atoms and three carbon atoms, and is in the dihydrogen state at positions 4 and 5. Position 3 is connected to the carboxylic anhydride structure, which is formed by the removal of a molecule of water from two carboxylic groups.
Overall, the chemical structure of this compound is based on 4,5-dihydro-1H-pyrazole-3-carboxylic anhydride, which is connected to a specific group of 1,2,3,4-tetrahydroquinoline-1-group at position 2, thus forming a unique chemical structure. This structure endows the compound with specific physical and chemical properties, which may have important applications and research values in many fields such as organic synthesis and medicinal chemistry.
What are the physical properties of 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole nitrate?
2-%281%2C2%2C3%2C4-%E5%9B%9B%E6%B0%A2%E8%90%98-1-%E5%9F%BA%29-4%2C5-%E4%BA%8C%E6%B0%A2-1H-%E5%92%AA%E5%94%91%E7%A1%9D%E9%85%B8%E7%9B%90%E7%9A%84%E5%85%B7%E4%BD%93%E5%88%86%E5%AD%90%E5%BC%8F%E4%B8%BAC
This compound is usually in the [specific form of [specific color], such as crystal, powder, etc.] at room temperature and pressure. The melting point is about [X] ° C, which makes the substance undergo a phase transition from solid to liquid at a certain temperature. The boiling point is around [X] ° C. When this temperature is reached, the substance will transform from liquid to gaseous.
Its solubility in common solvents also has certain characteristics. The solubility in water is relatively [high or low], mainly because the polar groups such as hydroxyl and carboxyl groups contained in its molecular structure interact with water molecules to form hydrogen bonds and other degrees. In organic solvents such as ethanol and ether, the solubility is different. In ethanol, the solubility is relatively [specific situation]. This is due to the polarity of ethanol and the interaction with the possible Van der Waals force and hydrogen bond between the molecules of the compound.
In terms of density, it is about [X] g/cm ³, which reflects the mass of the substance per unit volume. When mixed with other substances or performing related physical processes, the density is an important reference index.
In addition, the substance may have a certain odor. The odor characteristic is [specific odor description]. This odor characteristic is related to factors such as its molecular structure and volatility. At the same time, its refractive index is about [X], and as an optical property of the substance, it is of great significance for the identification and analysis of the substance in the field of optics and purity detection.
What are the synthesis methods of 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole nitrate?
To prepare 2 - (1,2,3,4 - tetrahydronaphthalene - 1 - yl) - 4,5 - dihydro - 1H - pyrazole carboxylic anhydride, there are many methods, as follows:
One of them is to start with 1,2,3,4 - tetrahydronaphthalene - 1 - amine, through diazotization reaction to obtain diazonium salt, and then react with suitable nucleophilic reagents, introduce key intermediates, and then convert in multiple steps to construct pyrazole ring, and finally dehydrate to anhydride. In this process, the diazotization reaction needs to precisely control the temperature and pH to prevent side reactions. In the subsequent cyclization step, suitable catalysts and reaction conditions need to be selected to promote cyclization and proceed efficiently.
Second, aromatics containing corresponding substituents can be started, and side chains can be introduced through the Fu-gram reaction to build a basic skeleton. Then through a series of reactions such as reduction, cyclization, and oxidation, the target structure is gradually formed. When the Fu-gram reaction, the activity and selectivity of the reactants need to be considered, and the appropriate catalyst and solvent should be selected. In the reduction step, the appropriate reducing agent should be selected according to the characteristics of the substrate to ensure the selectivity of the reaction.
Third, heterocyclic compounds are used as raw materials and synthesized through functional group conversion and cyclization reaction. For example, select nitrogen-containing heterocycles, modify their specific positions, introduce the desired substituents, and then cyclize to construct pyrazole rings, and then form anhydrides. This route requires in-depth understanding of the activity and selectivity of heterocyclic reactions, rational design of reaction sequences, and improvement of yield and purity.
During the synthesis process, each step of the reaction needs to precisely adjust the reaction conditions according to the characteristics of the substrate and the target product, select appropriate reagents and catalysts, and closely monitor the reaction process to optimize in time to achieve the purpose of efficient and high-purity synthesis.
In what fields is 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole nitrate used?
2-%281%2C2%2C3%2C4-%E5%9B%9B%E6%B0%A2%E8%90%98-1-%E5%9F%BA%29-4%2C5-%E4%BA%8C%E6%B0%A2-1H-%E5%92%AA%E5%94%91%E7%A1%9D%E9%85%B8%E7%9B%90, this is a complex chemical formulation. It has applications in many fields, as detailed below:
** Medicine **: This substance contains specific structures and properties, or can act on specific targets in the human body. With its ability to regulate certain biological activities, it may be used to develop new drugs. For example, by virtue of its interaction with specific proteins or enzymes, or can regulate biochemical reactions in the body, it provides new opportunities for the treatment of specific diseases. For some diseases caused by imbalance of biological activities, it may be adjusted by this substance to achieve therapeutic effect.
** Materials Science **: Because of its unique chemical composition and structure, or can be used to prepare materials with special properties. For example, in the synthesis of polymer materials, the introduction of this material structure unit may endow the material with better stability, flexibility or special optical and electrical properties. In the preparation of new functional materials, it may be used as a key additive to optimize material properties and meet the needs of special materials in different fields.
** Agricultural field **: This substance may affect the growth and development of crops. Or it can be used as a plant growth regulator to regulate plant physiological processes, such as promoting seed germination and enhancing plant stress resistance. Or it can be used to develop new pesticides. With its special mechanism of action against certain pests or pathogens, it can achieve more efficient and environmentally friendly pest control and help sustainable agricultural development.
** Fine chemical field **: It is often used to synthesize fine chemicals with special functions. For example, in the preparation of fragrances, coatings, inks and other products, its unique chemical properties can be used to improve product performance and quality. In the synthesis of fragrances, it may endow fragrances with unique aroma and stability; in the preparation of coatings and inks, it may improve its adhesion, weather resistance and other properties to meet the diverse needs of fine chemical products.
What is the safety of 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-imidazole nitrate?
This substance is called 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-pyrazolecarboxylic anhydride, and its safety needs to be considered in many aspects.
From the chemical structure, it contains tetrahydronaphthalene, pyrazole ring and acid anhydride structure. The acid anhydride structure has certain chemical activity, and can be hydrolyzed into corresponding carboxylic acids in contact with water, which may be corrosive. If it comes into contact with the skin, eyes, or causes burns or irritation, direct contact should be avoided during operation.
In terms of reactivity, pyrazole ring and tetrahydronaphthalene may participate in a variety of chemical reactions. Under specific conditions, the nitrogen atom on the pyrazole ring can undergo reactions such as nucleophilic substitution and metal catalytic coupling; tetrahydronaphthyl may be involved in oxidation, substitution and other reactions. The reaction conditions are not properly controlled or dangerous, such as the reaction is out of control, toxic by-products are produced, etc. The reaction conditions should be strictly controlled during operation.
In terms of stability, under normal storage conditions, if it is far away from high temperature, open flame, strong oxidant, etc., it is relatively stable. However, high temperature, light and high humidity environments may affect the stability and trigger reactions such as decomposition and polymerization, so it should be stored in a cool, dry and well-ventilated place.
Due to the lack of specific toxicological data of this substance, it is difficult to accurately assess the potential toxicity to biological However, studies on structural analogs have shown that some compounds containing pyrazole rings and naphthyl groups have certain biological activities and may have acute toxicity, chronic toxicity, teratogenicity, mutagenicity, etc. When using, it is necessary to refer to the toxicological information of similar structural compounds and take protective measures.
Operating 2- (1,2,3,4-tetrahydronaphthalene-1-yl) -4,5-dihydro-1H-pyrazole formic anhydride, be sure to follow safety operating procedures, wear protective clothing, gloves, goggles and other protective equipment, operate in a fume hood, avoid inhalation, intake and skin contact, strictly control reaction conditions and storage environment, and ensure the safety of personnel and the environment.