1H-imidazole-5-carbonitrile

1H-imidazole-5-formonitrile is an organic compound with a wide range of uses in many fields. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of drugs. The structural properties of the Gainimidazole ring endow compounds with diverse biological activities. By modifying its structure, new drugs with antibacterial, antiviral, and antitumor effects can be created. For example, some compounds synthesized on this basis can effectively inhibit the proliferation of specific tumor cells, providing a new path for the development of anti-cancer drugs.
In the field of materials science, 1H-imidazole-5-formonitrile also has its uses. Can participate in the preparation of functional materials, such as for the synthesis of polymers with special optical and electrical properties. After polymerization with other monomers, the resulting materials may exhibit unique properties in the field of optoelectronics, such as good conductivity or fluorescence properties, which are expected to be applied to organic Light Emitting Diodes, sensors and other devices.
In the field of catalysis, this compound may act as a ligand to form a highly efficient catalyst by complexing with metal ions. Such catalysts can exhibit high activity and selectivity in organic synthesis reactions, promoting more efficient and precise reactions. For example, in some coupling reactions, the reaction yield and product purity can be significantly improved.
In addition, 1H-imidazole-5-formonitrile may also have potential uses in the field of agricultural chemistry. It can be used as a raw material to synthesize biologically active pesticides for pest control and help the efficient and sustainable development of agricultural production. In conclusion, 1H-imidazole-5-formonitrile has important value and broad application prospects in many fields due to its unique structure and properties.

1H-imidazole-5-formonitrile, this material property is special, related to the chemical industry, and is important for research. Its shape, under normal conditions, is white to off-white crystalline powder, pure in appearance, uniform in quality and fine, like snow condensation, with a good crystalline state, this shape is easy to identify and use.
Its melting and boiling properties, the melting point is about 168-172 ℃, when the temperature reaches this point, the solid transition fluid state, intermolecular force change, crystal lattice dispersion. Although the boiling point data has not been widely disseminated, it is inferred according to its structure and homologues. The boiling point is quite high, and strong heat is required to enable the molecules to escape the liquid phase. In terms of solubility, it is easily soluble in organic solvents such as dimethyl sulfoxide (DMSO) and N, N-dimethylformamide (DMF), but slightly soluble in water. Due to the fact that there are both hydrophilic nitrogen heterocycles and hydrophobic cyano groups in the molecule, the hydrophilic and hydrophobic phase is prepared, and the hydrosolubility is limited. In organic solvents, it is suitable for Van der Waals force and hydrogen bond between solvent molecules, so it dissolves.
Good stability, normal contact with air and water, chemical stability, and reaction in case of strong acid, strong alkali or high temperature. In case of strong acid, the cyanyl group is hydrolyzed to a carboxyl group; in case of strong alkali, under specific conditions, the imidazole ring or open ring is used for this stability to comply with regulations and ensure its purity.
The density of this substance is about 1.3 g/cm ³, which is moderate compared with common organic compounds, reflecting the compactness of its molecular stacking.
1H-imidazole-5-formonitrile has unique physical properties and is a key raw material in the fields of organic synthesis and drug development. It needs to be known for its properties in order to improve its performance.

The chemical synthesis of 1H-imidazole-5-formonitrile is an important task in chemical technology. In the past, it was often started with a specific raw material. First, a nitrogen-containing heterocyclic precursor is taken, accompanied by appropriate reagents and conditions, so that it can react.
If you start with an imidazole derivative with a specific substituent, add a cyanide reagent, such as potassium cyanide or a cyanide source with similar activity, in a suitable solvent, such as an aprotic solvent. During the reaction, the temperature needs to be carefully controlled, usually in a mild heating state, so that the two can work effectively. Among them, the polarity of the solvent and the pH of the reaction environment are both affected, so fine adjustment is required. < Br >
There are also other ways of synthesis. Or first construct part of the structure of the imidazole ring, and then introduce the cyanyl group. First, the compound containing active hydrogen and the nitrile derivatives with electrophilic activity, under the catalysis of base, gradually construct the imidazole ring and introduce the cyanyl group. The type and amount of base have a great influence on the reaction process and product yield. For example, the choice of organic base or inorganic base depends on the characteristics of the substrate.
There is also a method of using transition metal catalysis. Select suitable transition metal catalysts, such as palladium, copper and other metal complexes, to catalyze the reaction of nitrogen-containing substrates with cyanide sources. In this process, the choice of ligand is also the key, which can adjust the activity and selectivity of the metal, so that the reaction can efficiently and regioselectively generate 1H-imidazole-5-formonitrile. The optimization of reaction conditions, such as reaction time, temperature, catalyst dosage, etc., needs to be repeatedly explored to achieve the best synthesis effect.

The price range of 1H-imidazole-5-formonitrile in the market is difficult to determine. This is due to various reasons, resulting in fluctuations in its price.
Looking at the supply and demand of materials, if the supply exceeds the demand, the price may drop; if the demand exceeds the supply, the price will rise. And the cost of its system is also important. The price of raw materials, labor costs, and equipment resources can all make the cost different, which in turn affects the price in the market.
Furthermore, the merchants are different, and their pricing is also different. Big merchants may have small profits due to large quantities, while small merchants may have high prices due to high costs. And the competitive state of the market also affects their prices. If there are many competing products, it is a competition for the market, and the price may be more flexible.
Although it is difficult to determine the exact price range, it is possible to go to the market of chemical raw materials, online business platforms, or consult people in the industry to check the approximate price.

1H-imidazole-5-formonitrile is one of the organic compounds. There are many manufacturers, and there are many operators in China.
There are companies such as Shanghai search banner biochemical technology joint stock company, which is quite famous in the supply of chemical reagents. It is also involved in the production and supply of 1H-imidazole-5-formonitrile. The quality of its products is acceptable and the supply is quite stable. It is often used by scientific research institutions and enterprises.
Another example is Tixi Ai (Shanghai) Chemical Industry Development Co., Ltd., which is a foreign-funded enterprise. It has accumulated many years and experience in the field of fine chemical manufacturing. The 1H-imidazole-5-formonitrile produced by it has exquisite craftsmanship and high quality, and has also won praise in the industry.
In addition, Beijing Inokai Technology Co., Ltd. is also a manufacturer of 1H-imidazole-5-formonitrile. Our company focuses on chemical supply, producing 1H-imidazole-5-formonitrile, with a variety of categories, which can meet the needs of different customers, and the service is also thoughtful, which is praised by many customers.
In addition, overseas, there are also manufacturers of this compound. For example, Sigma-Aldrich is a world-renowned chemical supplier. Its 1H-imidazole-5-formonitrile products are very popular in the international market and are renowned worldwide for their high quality and excellent service.
All these manufacturers contribute to the production of 1H-imidazole-5-formonitrile, making it widely used in scientific research, industry and other fields.