1h Imidazole 5 Acetonitrile
quinoline thiophene imidazole thiazole

1H-Imidazole-5-acetonitrile

    Specifications

    HS Code

    185713

    Chemical Formula C5H5N3
    Molecular Weight 107.11 g/mol
    Appearance Solid (usually white or off - white powder)
    Melting Point Typically in a certain range (data needed for exact value)
    Solubility In Water Low solubility, sparingly soluble
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Pka Value Relevant to its acidic - basic properties (data needed for exact value)
    Odor Odorless or very faint odor

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    General Information
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    Frequently Asked Questions

    As a leading 1H-Imidazole-5-acetonitrile supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the main uses of 1H-Imidazole-5-acetonitrile?
    1H-imidazole-5-acetonitrile is one of the organic compounds. It has a wide range of uses and is involved in many fields.
    First, in the field of pharmaceutical chemistry, this compound is often a key intermediate. Due to its unique chemical structure, it can participate in many drug synthesis reactions. Through clever chemical reactions, it can be converted into compounds with specific pharmacological activities, which can be used to develop new drugs to fight various diseases, such as antibacterial and antiviral drugs. It may play an important role.
    Second, in the field of materials science, 1H-imidazole-5-acetonitrile also has a place. It can be used to prepare materials with special properties, such as some functional polymer materials. During the material synthesis process, it can be used as a reaction monomer or modifier to endow the material with special properties such as better stability and conductivity, and then meet the special needs of materials in different fields.
    Third, in the field of organic synthetic chemistry, it is an important synthetic building block. Chemists can build more complex organic molecular structures through a series of organic reactions according to their structural characteristics. With the help of various reaction conditions, precise control of the structure and properties of the target product can be achieved, providing assistance for the development of organic synthetic chemistry.
    What are the physical properties of 1H-Imidazole-5-acetonitrile?
    1H-imidazole-5-acetonitrile is one of the organic compounds. Its physical properties are crucial and indispensable in chemical research and related applications.
    First of all, its appearance, under normal conditions, 1H-imidazole-5-acetonitrile is mostly white to off-white crystalline powder, which is easy to observe and handle. Its powder texture is fine and the particle distribution is relatively uniform, which has a significant impact on many reactions and preparation processes.
    times and melting point, the melting point of this substance is about within a specific range. The determination of melting point is an important basis for identification and purity judgment. Accurate melting point data help researchers clarify the purity of the substance. If the melting point deviates from the established range, it suggests that there may be impurities mixed in.
    Furthermore, when it comes to solubility, 1H-imidazole-5-acetonitrile exhibits a certain solubility in specific organic solvents. In organic solvents such as dichloromethane, N, N-dimethylformamide, etc., it can be moderately dissolved. This solubility facilitates its operation in organic synthesis reactions. Researchers can choose suitable solvents according to their characteristics to promote the smooth progress of the reaction. However, in water, its solubility is relatively limited, which is also something to pay attention to during operation.
    The stability of 1H-imidazole-5-acetonitrile is repeated. Under normal environmental conditions, 1H-imidazole-5-acetonitrile still has a certain stability. In case of extreme conditions such as high temperature, strong oxidizing agent or strong acid and alkali, chemical reactions may occur, resulting in structural changes. Therefore, when storing and using, environmental factors need to be properly controlled to ensure the stability of its chemical structure and properties.
    The physical properties of 1H-imidazole-5-acetonitrile are of great significance in organic synthesis, medicinal chemistry and other fields. With in-depth understanding of its physical properties, researchers rationally plan experimental steps and optimize reaction conditions, so as to promote the development of related fields.
    1H-Imidazole-5-acetonitrile chemical synthesis methods
    1H-imidazole-5-acetonitrile is also an organic compound. There are several common methods for its synthesis.
    First, use a suitable nitrogen-containing heterocyclic compound as the starting material. Imidazole derivatives can be taken first, and cyanomethyl is introduced through specific reaction conditions. Among them, the control of the reaction conditions is very critical. It is necessary to choose the appropriate reagent and catalyst depending on the characteristics of the raw materials used. If the method of base catalysis is used, when the type and dosage of base are carefully selected, the strength and amount of base cover have a great impact on the reaction process and product yield.
    Second, start from nitriles. Find suitable nitriles and construct imidazole rings through a series of reactions. In the meantime, it may involve steps such as nucleophilic substitution and cyclization. During nucleophilic substitution, the activity, reaction temperature and time of the reagents involved are all key points. If the temperature is too high or too low, the reaction deviation can be caused, and the non-yield is low, that is, the product of miscellaneous side effects.
    Or, react with a carbonyl-containing compound with a nitrogen-containing reagent. The two undergo various changes such as condensation and cyclization to form 1H-imidazole-5-acetonitrile. During the condensation process, the choice of solvent should not be underestimated, and different solvents have different reaction rates and selectivity.
    Every step of the synthesis requires fine operation and close monitoring of the reaction process. Such as thin layer chromatography, nuclear magnetic resonance and other means to determine the progress of the reaction and the purity of the product. And the post-treatment steps are also important, through extraction, distillation, recrystallization and other methods to obtain pure 1H-imidazole-5-acetonitrile.
    What is the price range of 1H-Imidazole-5-acetonitrile in the market?
    I look at what you are asking, but I am inquiring about the price range of 1H-imidazole-5-acetonitrile in the market. However, the price of this chemical product often changes for many reasons, and it is difficult to determine the exact number.
    First, the quality is related to the price. If it is high purity and few impurities, the price will be high; on the contrary, the purity is slightly lower, and the price may be slightly lower. Second, the amount of purchase also has an impact. When purchasing in bulk, merchants may give discounts to promote sales, and the price should be lower than that of sporadic purchases. Third, the supply and demand situation of the city also affects the price. If there are many people who want it, but the supply is small, the price will rise; if the supply exceeds the demand, the price will fall.
    And the market fluctuates constantly, the price changes rapidly, and the price varies from season to season. Or due to the difficulty of obtaining raw materials, the improvement of production processes, and the increase or decrease of transportation costs, the price can fluctuate. Therefore, to know the exact price range, you must consult the chemical reagent suppliers in detail, or check the records of recent market transactions, in order to obtain a more accurate number. Although it is difficult to determine the exact price of the product, according to common sense, because the synthesis of the product may have a certain degree of complexity, and it is used in specific fields, its price should not be low. As for the specific price, it is impossible to obtain it without on-site detailed investigation.
    What are 1H-Imidazole-5-acetonitrile storage conditions?
    1H-imidazole-5-acetonitrile is one of the organic compounds. The storage conditions are quite important, which are related to the stability and quality of this substance.
    First, it must be stored in a cool place. High temperature can easily cause chemical reactions, or cause decomposition and deterioration. Therefore, it is advisable to choose a place with a lower temperature to ensure the stability of its chemical properties. And the indoor temperature should be maintained within a specific range, not too high, to prevent unexpected changes.
    Second, a dry environment is indispensable. If this compound encounters water vapor, it is very susceptible to moisture. After being damp, it may cause reactions such as hydrolysis, which will damage its purity and characteristics. Where it is stored, it must be kept dry, and a desiccant can be placed next to it to absorb the surrounding water vapor.
    Third, it should be avoided from light. Under light, or photochemical reactions, its structure can be changed. Therefore, the storage device should be selected with good light shielding, such as a brown bottle, so that light is difficult to penetrate and protect its components from light.
    Fourth, the storage device should also be appropriate. Containers with stable chemical properties and no reaction should be selected. Glass materials are often preferred because of their good chemical inertness and can effectively protect 1H-imidazole-5-acetonitrile.
    Also, the storage place must be kept away from fire sources, heat sources and oxidants. This compound may be flammable to a certain extent, and it may be dangerous in case of fire or hot topic. Contact with the oxidant or promote its oxidation reaction will damage its inherent properties.
    In this way, keep all storage conditions to ensure the quality and stability of 1H-imidazole-5-acetonitrile for subsequent use.