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1H-Imidazole-4-carboxamide, what is the chemical structure of 5-amino- 5-amino-4-imidazolylcarboxamide
The chemical structure of 5-amino-4-imidazole carboxamide (5-amino-4-imidazolylcarboxamide, also known as 1H-imidazole-4-formamide, 1H-Imidazole-4-carboxamide) is composed of an imidazole ring with a formamide group and an amino group.
Look at the imidazole ring, which is a five-membered heterocycle containing two nitrogen atoms and is aromatic. The electronic properties of the nitrogen atoms in the ring have a great influence on the chemical activity and reactivity of the molecule. The formamide group (-CONH _ 2) is connected to the 4-position of the imidazole ring. In the formamide group, the carbonyl group (C = O) is connected to the amino group (-NH ²), and the carbon of the carbonyl group has a certain positive electricity, which is vulnerable to attack by nucleophilic reagents; the nitrogen atom of the amino group has lone pair electrons, which can participate in the formation of hydrogen bonds or serve as nucleophilic check points.
And the amino group (-NH ²) connected to the 5-position is also an important structural part of the molecule. The nitrogen atom of the amino group also has lone pair electrons, which can exhibit alkalinity and can react with acids to form salts. Its presence not only affects the electron cloud distribution of the molecule, but also has a significant impact on the polarity, water solubility and biological activity of the molecule.
The interaction of various parts of this chemical structure jointly determines the physical, chemical and biological properties of 5-amino-4-imidazole formamide, and plays a key role in many chemical reactions and biological processes.
1H-Imidazole-4-carboxamide, what are the main uses of 5-amino- 5-amino-4-imidazolylcarboxamide
5-Amino-4-imidazole-carboxamide (5-amino-4-imidazolylcarboxamide, also known as 1H-imidazole-4-carboxamide, 1H-imidazole-4-carboxamide) has important uses in many fields and is a chemical substance that cannot be ignored.
In the field of medicinal chemistry, it is widely used as a key intermediate in drug synthesis. Many bioactive compounds are constructed from it. Due to its unique structure, it can participate in a variety of chemical reactions, whereby drug molecules with complex structures and specific pharmacological activities can be synthesized. For example, in the development of some anti-tumor drugs, 5-amino-4-imidazolecarbonamide plays an indispensable role in helping humans overcome cancer problems.
In the field of biochemical research, this substance also plays an important role. It participates in the process of purine nucleotide biosynthesis and is an important intermediate product of this process. By studying its metabolic pathway and related regulatory mechanisms in organisms, scientists can gain insight into basic life activities such as cell growth and proliferation, providing key clues for elucidating the mysteries of life and exploring the pathogenesis of diseases.
In the field of agriculture, 5-amino-4-imidazolecarbonamide also has potential application value. Some studies have shown that it may have an impact on plant growth and development, or can be used as a raw material for plant growth regulators to regulate crop growth, improve crop yield and quality, and help sustainable agricultural development.
In short, 5-amino-4-imidazole formamide has shown broad application prospects in many fields such as medicine, biology, and agriculture due to its unique chemical structure and diverse chemical reactivity. It is of great significance for promoting scientific research and technological development in various fields.
1H-Imidazole-4-carboxamide, what are the physical properties of 5-amino- 5-amino-4-imidazolylcarboxamide
5-Amino-4-imidazole carboxamide (5-amino-4-imidazolylcarboxamide, also known as 1H-imidazole-4-carboxamide, 1H-imidazole-4-carboxamide) is a kind of organic compound. Looking at its physical properties, under normal temperature and pressure, this substance is mostly white to light yellow crystalline powder, just like frost and snow, delicate and pure. Its smell is almost odorless, like a quiet place, silent. < Br >
When it comes to solubility, this compound has a certain ability to dissolve in water, just like raindrops into a stream, which can be partially dispersed; while in common organic solvents, such as ethanol, ether, etc., its solubility is quite limited, just like the intolerance of oil and water, only slightly soluble or almost insoluble.
Furthermore, its melting point is about 210-220 ° C. When the temperature rises to this point, it is like melting and melting, gradually transforming from solid to liquid, and initiating another form change. The various physical properties are inherent in its characteristics, just like human nature, and are of vital significance in chemical research and practical applications, providing an indispensable foundation for exploring more of its mysteries.
1H-Imidazole-4-carboxamide, what is the synthesis method of 5-amino- 5-amino-4-imidazolylcarboxamide
5-Amino-4-imidazolium carboxamide (5-amino-4-imidazolylcarboxamide, i.e. 1H-imidazole-4-carboxamide, 1H-Imidazole-4-carboxamide, 5-amino -) is synthesized as follows:
The starting material is readily available nitrogen-containing heterocycles and amino and carboxyl-containing related raw materials. First, the nitrogen-containing heterocycles are placed in a specific reaction vessel, and an appropriate amount of catalyst and solvent is added. This catalyst can promote the reaction, and the solvent provides a suitable environment for the reaction. Heat to a certain temperature to keep the reaction system in a stable state, so that the nitrogen-containing heterocycle undergoes preliminary transformation to form an intermediate with specific activity. After
, the raw material containing amino groups is slowly added to the above reaction system in a certain proportion. During this period, close attention should be paid to the temperature, pH and other conditions of the reaction, and the stability of the pH of the system should be maintained by dropwise addition of acid-base regulators. As the reaction progresses, the amino group gradually undergoes a substitution reaction with the intermediate, and the structure of the imidazole ring and the amino group connection of the target product is gradually constructed.
After the amino substitution reaction is basically completed and the expected reaction phenomenon occurs in the reaction system, the raw material containing carboxyl groups is then put into the reaction. This process also requires precise control of the reaction conditions. The carboxyl group and the formed structure are further condensed to form 5-amino-4-imidazole formamide.
After the reaction is completed, the reaction mixture is post-processed. The target product is separated by filtration, extraction and other means, and then purified by recrystallization to remove impurities, improve the purity of the product, and finally obtain high-purity 5-amino-4-imidazole formamide.
1H-Imidazole-4-carboxamide, what is the price range of 5-amino- 5-amino-4-imidazolylcarboxamide in the market?
I don't know the price range of 5-amino-4-imidazole carboxamide (5-amino-4-imidazolylcarboxamide, also known as 1H-imidazole-4-carboxamide, 1H-Imidazole-4-carboxamide) in the market. Due to the unpredictable market conditions, the price of this compound is affected by many factors.
First, the purity has a great impact. If the purity is very high and almost flawless, its price will be high; if it contains impurities and the purity is slightly inferior, the price may be low. Second, the trend of supply and demand is also the key. If there are many people who want it, if the supply is small, the price will go up; conversely, if the supply exceeds the demand, the price will be depressed. Third, the difficulty of preparation and the cost of raw materials are also related. The preparation method is complicated, and the rare price of raw materials is high, and the price of finished products is also high.
Or you can consult various chemical reagent suppliers, such as Sinopharm Group Chemical Reagent Co., Ltd., search banner reagent company, etc., who may be able to tell the current price in detail. Or refer to the price information published on the chemical product trading platform, but such prices are not constant and often fluctuate with market conditions. To get an accurate price, you need to check all relevant channels in real time.