1H-Imidazole-4-carboxaldehyde, 5-(1,1-dimethylethyl)-

1H-imidazole-4-formaldehyde, 5- (1,1-dimethylethyl), this substance has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate, which can help synthesize many compounds with special pharmacological activities. Due to its unique structure and activity, imidazole can precisely bind to targets in vivo, and can be used as a base to construct drugs, or can be used to treat a variety of diseases, such as inflammation, tumors, etc.
In the field of materials science, it can participate in the preparation of functional materials. With its own aldehyde and tert-butyl properties, it can adjust the physical and chemical properties of materials, such as improving material solubility and stability, or giving materials specific reactivity check points, providing opportunities for material modification innovation. < Br >
In the field of organic synthesis, as an important building block, it can build complex organic molecular structures by condensation and addition of aldehyde groups with other functional groups, expand the types and properties of organic compounds, and contribute to the development of organic synthetic chemistry.
Its applications in different fields are due to the reactivity and characteristics endowed by the unique molecular structure, opening up new paths for many scientific research and industrial production, helping humans make progress and breakthroughs in medicine, materials and many other aspects.

1H-imidazole-4-formaldehyde, 5- (1,1-dimethylethyl), the physical properties of this substance are as follows:
Its appearance is mostly crystalline solid, and due to the specific arrangement of molecular structure, the intermolecular forces show corresponding characteristics, and then form this form. The melting point is [X] ° C, and this value is determined by the strength of the intermolecular interaction. At this temperature, the molecule obtains enough energy to overcome the lattice energy and realize the transition from solid to liquid.
In terms of solubility, it exhibits certain solubility in organic solvents such as ethanol and dichloromethane. This is due to the interaction between the polar parts of its molecular structure and the organic solvent molecules, such as hydrogen bonds or van der Waals forces, which enable it to disperse in these solvents. However, the solubility in water is poor, due to the large proportion of hydrophobic groups in the whole molecule and the weak interaction with water molecules, it is difficult to form a stable dispersion system.
The density is about [X] g/cm ³, which reflects the mass of the substance per unit volume and is affected by the relative mass of the molecules and the degree of accumulation of the molecules in the crystal structure.
This substance is relatively stable at room temperature and pressure, but if it is exposed to high temperatures, strong oxidants or specific reaction conditions, the aldehyde group and imidazole ring in its structure may undergo chemical reactions, resulting in changes in physical properties. For example, aldehyde groups can participate in oxidation, condensation and other reactions. Once the reaction occurs, its original crystalline morphology, melting point, solubility and other physical properties will change due to changes in molecular structure.

To prepare 5- (1,1-dimethylethyl) -1H-imidazole-4-formaldehyde, the method is as follows:
First take a suitable starting material, and choose an imidazole compound containing the corresponding substituent as the group. If you find an imidazole derivative with a suitable protecting group and potential conversion to aldehyde and tert-butyl.
One method is to modify the specific position of the imidazole ring first. In a suitable reaction system, with specific reagents and conditions, tert-butyl is introduced into the 5-position of the imidazole ring. In this process, attention should be paid to the choice of reaction solvent, such as the use of aprotic solvents, such as dichloromethane, N, N-dimethylformamide, etc., which can facilitate the reaction. The reagents used may be tert-butyl alkylation reagents, such as tert-butyl halide, under the catalysis of bases, tert-butyl is introduced. The base can be selected from potassium carbonate, tert-butyl alcohol, etc., and the reasonable choice is based on the activity and selectivity of the reaction.
After the successful introduction of tert-butyl, the construction of 4-aldehyde groups will be focused on. At this time, a suitable oxidizing agent can be selected. If you want to oxidize the alcohol hydroxyl group from the 4-position to the aldehyde group, you can use a mild oxidizing agent, such as Dyce-Martin oxidizing agent (DMP). In a low temperature and anhydrous environment, the 5- (1,1-dimethylethyl) imidazole derivative containing the 4-position alcohol hydroxyl group is reacted with DMP in an organic solvent, and the hydroxyl group can be oxidized to the aldehyde group to obtain 5- (1,1-dimethylethyl) -1H-imidazole-4-formaldehyde.
Or construct the 4-position aldehyde group first, and then introduce the 5-position tert-butyl group. Starting with imidazole derivatives containing the 4-position aldehyde group, the tert-butyl group is introduced at the 5-position under specific reaction conditions. However, this route should pay attention to the fact that the aldehyde group may need to be properly protected during the introduction of the tert-butyl group to prevent the aldehyde group from participating in unnecessary side reactions. After the introduction of the tert-butyl group, the protective group of the aldehyde group is removed, and the target product can also be obtained. All these methods need to carefully control the reaction conditions and monitor the reaction process to improve the yield and purity of the product.

I don't know what the market price of 1H-imidazole-4-formaldehyde, 5- (1,1-dimethylethyl) is. This is a fine chemical, and its price often varies due to many factors.
First, the quality of the origin is related to the price. If the origin is excellent, the craftsmanship is exquisite, and the quality is high, the price may be high; if the origin is crude, the quality is slightly inferior, and the price may be slightly lower.
Second, the trend of market supply and demand is also the main reason. If there are many people who want it, and the supply is small, the price will rise; if there are few people who want it, the supply will exceed the demand, and the price will drop.
Third, the quantity also affects the price. If you buy in bulk, there may be discounts, and the unit price is lower; if you buy in small quantities, the unit price may be higher.
Furthermore, the times are different, and the prices are also different. Changes in raw material prices, increases and decreases in transportation costs, and the impact of policies and regulations will all cause their prices to fluctuate.
For the exact price, you can consult the chemical product trading platform, chemical reagent supplier, or negotiate directly with relevant manufacturers to get the exact price.

1H-imidazole-4-formaldehyde, 5- (1,1-dimethylethyl), this substance is related to safety and needs to be cautious.
This chemical substance may have specific chemical activity and reaction characteristics. Before use, be sure to check its physical and chemical properties carefully, understand its melting point, boiling point, solubility, etc., so that the appropriate conditions and methods can be selected during operation to avoid danger caused by improper conditions.
At the storage end, look for a cool, dry and well-ventilated place, away from fire and heat sources. Because of its sensitivity to temperature and humidity, improper storage environment, or deterioration, or even cause safety accidents. And should be stored separately from oxidants, acids, alkalis, etc., to prevent mutual reaction.
When operating, it is necessary to strictly follow the standardized procedures. Apply appropriate protective measures, wear protective clothing, protective gloves and goggles to prevent contact with the skin and eyes. If you work in a poorly ventilated place, you need to prepare effective ventilation equipment to prevent the accumulation of steam or dust, poisoning and other accidents.
In addition, it is also important to know its emergency response methods. If you accidentally come into contact with the skin, you should quickly rinse with a large amount of flowing water; if it enters the eyes, you need to immediately open the eyelids, rinse with flowing water or normal saline, and seek medical attention. In case of fire, you need to choose the appropriate extinguishing agent according to its nature, and do not act blindly.
All aspects of this chemical substance must be handled with caution and without any slack to ensure the safety of personnel and the environment.