1H-Imidazole-4,5-dicarboxylic acid dimethyl ester

1H-imidazole-4,5-dimethyl dicarboxylate is used in various fields of chemical industry and medicine.
In the field of chemical industry, it is often used as a raw material for organic synthesis. Based on this, many compounds with special structures and properties can be prepared. If combined with other organic reagents through a specific reaction path, it can build a complex organic molecular structure, laying the foundation for the creation of new materials, dyes, etc. Because its molecular structure contains imidazole ring and ester group, it gives it unique reactivity and chemical stability. In the process of organic synthesis, it can participate in a variety of reaction types, such as nucleophilic substitution, cyclization addition, etc., thereby expanding the types and functions of compounds.
In the field of medicine, it is also widely used. Or as a drug intermediate, it can assist in the synthesis of biologically active drug molecules. Due to its structural properties, it may affect the interaction between drugs and biological targets. Studies have shown that compounds containing imidazole structure often have certain pharmacological activities, such as antibacterial, anti-inflammatory, anti-tumor, etc. 1H-imidazole-4,5-dicarboxylate dimethyl ester may be chemically modified and modified to precisely target specific biological targets and exert therapeutic effects. In addition, in the process of drug development, it can provide a structural template for the optimization of lead compounds, and adjust the pharmacokinetic properties such as solubility, permeability and bioavailability of drugs through the modification of ester groups and other functional groups, so as to improve the pharmacokinetic properties of drugs.

1H-imidazole-4,5-dimethyl dicarboxylate, this is an organic compound with unique physical properties. It is white to light yellow crystalline powder at room temperature, and it looks fine, just like the micro of nature.
When it comes to the melting point, it is about 170-174 ° C. When the temperature gradually rises to the melting point, this thing is like ice and snow meeting warm sun, slowly melting from solid to liquid, this process seems to have an invisible hand, quietly changing.
Its solubility also has characteristics. It can be dissolved in common organic solvents such as dichloromethane and chloroform, just like fish entering water and melting freely. However, in water, the solubility is very small, just like oil and water are difficult to mix, and they are distinct.
The density of this object is about 1.32 g/cm ³. When placed in the hand, it can feel the authenticity of its texture and its weight is moderate. Its stability is acceptable. Under normal conditions, it can maintain its own structural integrity. In case of extreme environments such as strong acids and alkalis, it is also like a weak body that cannot be defeated by violent storms, and the structure may be damaged.
In addition, the vapor pressure of 1H-imidazole-4,5-dimethyl dicarboxylate is very low. Under normal temperature and pressure, it evaporates very slowly, just like a quiet lake, which is calm. Its smell is weak, if you don't sniff it carefully, it is almost invisible, like a spirit hidden in the world, low-key and mysterious.

The chemical synthesis of 1H-imidazole-4,5-dimethyl dicarboxylate is a key skill in the field of organic synthesis. The synthesis method often follows the following steps.
First, suitable starting materials, such as imidazole compounds with specific substituents, and reagents that can introduce carboxyl methyl ester groups, are co-located under specific reaction conditions. Common starting materials, or imidazole derivatives with active check points, and reagents with carboxyl methyl ester groups, or halogenated carboxylic acid esters.
At the beginning of the reaction, an appropriate reaction solvent should be selected, which can dissolve the reactants and has no adverse effect on the reaction process. Organic solvents such as dichloromethane, N, N-dimethylformamide are often taken.
Next, an appropriate amount of catalyst is added to the reaction system. The choice of this catalyst depends on the reaction rate and yield. For example, some organic bases or metal salt catalysts can effectively promote the progress of the reaction. Base catalysts may activate the reactants to make the reaction check point more active, while metal salts may play the role of coordination catalysis in the reaction.
When reacting, temperature and reaction time are also key factors. Generally speaking, the reaction temperature may be controlled within a certain range, depending on the specific reaction, or at room temperature to heated reflux interval. The reaction time needs to be based on the reaction process, and monitoring methods such as thin-layer chromatography can be used to determine the end point of the reaction in a timely manner to ensure that the reaction is sufficient and not excessive.
After the reaction is completed, the separation and purification of the product should not be underestimated. Column chromatography, recrystallization and other methods are often used. Column chromatography can achieve the separation of products and impurities by the difference in partition coefficients between different substances in the stationary phase and the mobile phase; recrystallization can obtain a pure product according to the solubility of the product and impurities in a specific solvent with the change of temperature.
In this way, through the selection of raw materials, the regulation of reaction conditions, the separation and purification of the product, etc., 1H-imidazole-4,5-dimethyl di This method of synthesis is a common way to obtain such compounds in organic synthetic chemistry.

What is the price of 1H-imidazole-4,5-dicarboxylic acid dimethyl ester in the market today? I will answer it with the ancient style of "Tiangong Kaiwu".
The price of goods in the city is variable and often varies depending on time, land, quality and supply and demand. For 1H-imidazole-4,5-dicarboxylic acid dimethyl ester, if you ask for it in various chemical workshops, its price may fluctuate between tens of gold and hundreds of gold per kilogram.
Looking at its texture, if it is pure and flawless, it is of high quality, and the price will be high; if there are a little impurities, although it is available, the price will be slightly reduced. And the distance of the earth is also related to the price. If it is available nearby, the freight will be saved, and the price will be easy; if it is transshipped far away, the freight will be added, and the price will increase.
And the trend of supply and demand, if there are many people who want it, but the goods are scarce, the price will rise; if the city is full, and there are few people who want it, the price will decrease. Therefore, if you want to know the exact price, you need to go to the city in person, consult the merchants, check its quality, and measure the supply and demand at the time to get its detailed price.

1H-imidazole-4,5-dicarboxylic acid dimethyl ester, this is a fine organic compound, and its storage conditions are quite critical.
To properly store this compound, the first environment is drying. Moisture is easy to cause its hydrolysis, which in turn damages the quality and purity. Therefore, when placed in a dry place, a desiccant can be prepared in the storage place to absorb the surrounding water vapor.
The second is temperature control. It should be stored in a cool environment, usually 2-8 ° C. High temperature can easily cause its chemical changes and cause it to deteriorate. If the temperature is too high, or the molecular structure is changed, the activity is lost.
Furthermore, avoid direct light. Light may cause photochemical reactions to occur, causing it to decompose or denature. An opaque container should be selected, or stored in a dark place.
When storing, also pay attention to isolation. Do not coexist with oxidizing agents, acids, bases and other chemically active substances to prevent dangerous chemical reactions.
In short, 1H-imidazole-4,5-dicarboxylate should be stored in a dry, cool, dark and isolated environment to ensure its quality and stability for subsequent use.