1h Imidazole 4 1 2 3 Dimethylphenyl Ethyl
quinoline thiophene imidazole thiazole

1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-

    Specifications

    HS Code

    233397

    Chemical Formula C14H16N2
    Molecular Weight 212.29 g/mol
    Appearance Solid (predicted, based on similar structures)
    Boiling Point Estimated high, due to aromatic and polar groups
    Melting Point Estimated to be in a solid - state ambient range
    Solubility In Water Low (hydrophobic due to large aromatic part)
    Solubility In Organic Solvents Moderate to high in non - polar and some polar organic solvents
    Density Estimated density based on similar aromatic compounds
    Flash Point Relatively high, as an organic nitrogen - containing compound
    Pka No exact value, but imidazole group can be basic

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    General Information
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    Frequently Asked Questions

    As a leading 1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -
    4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole, this is an organic compound. In terms of physical properties, it is mostly solid at room temperature, and the appearance is usually white to light yellow crystalline powder. It has a certain solubility in organic solvents, such as common ethanol and dichloromethane, etc. However, the solubility in water is relatively low.
    From a chemical point of view, the nitrogen atom of 1H-imidazole has lone pairs of electrons, which makes this compound weakly basic and can react with acids to form salts. The aromatic ring structure in its molecule gives it a certain stability, and the substituents on the aromatic ring will affect the distribution of its electron cloud, thereby changing the reactivity. Due to the presence of 2,3-dimethyl on the benzene ring, the steric resistance increases, which has a certain guiding effect on the type of reaction and the check point of the reaction it participates in. Under appropriate conditions, it can undergo reactions such as electrophilic substitution, and the substituents can affect the difficulty and substitution position of the reaction; it can also participate in nucleophilic reactions, showing unique chemical behaviors. Because its structure contains both aromatic rings and nitrogen-containing heterocycles, it is often used as a key intermediate in the field of organic synthesis for the construction of more complex organic molecular structures, and has potential applications in many fields such as pharmaceutical chemistry and materials science.
    What are the main uses of 1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -
    4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole, which has a wide range of uses. In the field of medicine, it may be a key drug synthesis intermediate. Through fine chemical synthesis techniques, it can be integrated into the molecular structure of many drugs, and the effect of treating diseases can be achieved by acting on specific targets. For example, when developing new antihistamine drugs, 4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole has a special chemical structure, which can precisely fit with histamine receptors, thereby exerting the effect of antihistamine and relieving allergic symptoms.
    In the field of materials science, it can be used as a polymer modifier. When added to a specific polymer system, 4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole interacts with the polymer molecular chain by its own active group, which significantly optimizes the mechanical properties and thermal stability of the polymer. For example, when preparing high-performance engineering plastics, adding this substance in an appropriate amount can effectively improve the strength and heat resistance of the plastic, and broaden its application range in high temperature and high load environments.
    In organic synthetic chemistry, it is an important building block for building complex organic molecules. Because its structure contains active check points, various organic compounds with different structures can be derived through various organic reactions, such as nucleophilic substitution, cyclization reaction, etc., providing rich possibilities for organic synthesis chemists to create novel structures and explore new reaction paths.
    What is the synthesis method of 1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -
    To prepare 4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole, the method is as follows:
    Take 2,3-dimethylacetophenone first, which is the key starting material. With its reaction with appropriate amination reagents, nitrile compounds can often be used to obtain the corresponding imine intermediates through condensation reaction. This step requires selecting mild reaction conditions, temperature control, control, so that the reaction is sufficient and less side effects.
    The imine intermediate is obtained, and then the cyclization reaction is carried out. A specific cyclization reagent is added, or under catalytic conditions, the intramolecular ring is formed to produce the prototype of 4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole. However, the initial product is not pure and still contains impurities.
    To carry out the purification, the recrystallization method can be used, and the suitable solvent can be selected to remove impurities by the difference in solubility to obtain a purer product. Column chromatography can also be used. According to the different adsorption properties of the product and impurities, it can be eluted with a suitable eluent to obtain a pure 4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole. Each method requires fine operation and fine adjustment of parameters according to the characteristics of the product in order to obtain satisfactory results and become the target compound.
    1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) - What is the price in the market?
    There is "1H-imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) " in the market, so it is difficult to know its price. These substances may be rare chemical reagents, and their price often varies depending on purity, origin, and supply and demand.
    If it is an ordinary chemical, and the preparation method is simple, the supply is sufficient, the price is flat. However, if its preparation is complicated, special raw materials and conditions are required, or the demand is rare, and it is only used for specific research or industrial purposes, its price is high.
    Furthermore, if it comes from a famous factory, the quality is high, and the price is also high; if it is produced by a small factory, the price may be slightly lower. And the amount of purchase also affects the price. If you buy in bulk, you can often get a discount.
    Because you don't know the specific details, it is difficult to determine what the price is in the market. To know the price, you can consult the chemical reagent supplier, or check on the relevant chemical product trading platform to get a more accurate price.
    What is the safety and toxicity of 1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -?
    There is a substance named 1H-imidazole, 4- (1- (2,3-dimethylphenyl) ethyl). The safety and toxicity of this substance are related to the safety of the user and cannot be ignored.
    Looking at its chemical conformation, the properties of such compounds often depend on their atomic connections and spatial arrangement. However, as far as this substance is concerned, there are no ancient recipes and classics to find out its details. Therefore, in order to know its safety and toxicity, it is necessary to test it according to today's scientific methods.
    Today's methods of testing poison are often tested on animals to observe their physiological changes and behavioral differences. If you try it on mice, put this substance and observe its diet, activities, and organs. If the rat eats less, moves slowly, and the organs are damaged, it indicates that the substance is toxic.
    And look at its feelings in the environment. If the substance is scattered in water and soil, check whether it is easy to decompose. If it is difficult to separate for a long time, it may accumulate in the body of the organism and cause ecological chaos.
    However, it is difficult to fully know its feelings for humans only when tested on animals. Humans are different from animals in physiology. Therefore, in order to ensure its safety in humans, it is necessary to conduct clinical trials cautiously to check its effects on the human body, such as whether there are allergies, organ injuries, or genetic changes. The safety and toxicity of 1H-imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) can not be determined overnight, and it must be subjected to multiple scientific inspections and detailed analysis of the results to know its impact on the human body and the environment, so as to ensure the safety of the user and the tranquility of the environment.