1h Imidazole 4 1 2 3 Dimethylphenyl Ethyl R
quinoline thiophene imidazole thiazole

1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-, (R)-

    Specifications

    HS Code

    903201

    Chemical Formula C15H18N2
    Molecular Weight 226.32 g/mol
    Appearance Solid (predicted)
    Boiling Point Estimated around 360 - 380 °C
    Melting Point Estimated range: 80 - 100 °C
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in common organic solvents like ethanol, dichloromethane
    Density Estimated density around 1.0 - 1.1 g/cm³
    Flash Point Estimated around 150 - 170 °C
    Pka Imidazole - NH pKa around 14 (estimated)

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    General Information
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    Frequently Asked Questions

    As a leading 1H-Imidazole, 4-(1-(2,3-dimethylphenyl)ethyl)-, (R)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -, (R) -?
    This is related to the chemical structure of (R) -4 - (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole. This compound, the imidazole ring is a group, and its 1 position is unsubstituted. It is active and can participate in various reactions. The 4 position is connected to a specific side chain, and the 1 - (2,3-dimethylphenyl) ethyl group in the side chain is connected by ethyl and 2,3-dimethylphenyl. Ethyl acts as a bridge to associate the phenyl group with the imidazole ring. In 2,3-dimethylphenyl, the phenyl ring is a hexagonal aromatic ring, which is connected to a methyl group at the 2 and 3 positions. The introduction of this methyl group changes the distribution of electron clouds in the benzene ring, which affects the molecular physics and chemical properties. (R) The configuration indicates that the compound has chirality, with asymmetric centers in the molecule, and the spatial arrangement of atoms or groups has a specific direction, which causes it to be specific to the rotation direction of polarized light. Such a structure endows this compound with unique chemical activities and physical properties. It may have important uses in organic synthesis, drug research and development, etc. Because of its unique structure, it can interact with specific biological targets, exhibit specific biological activities, or become potential drug lead compounds, or serve as special catalysts or intermediates in organic reactions.
    What are the physical properties of 1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -, (R) -?
    1H-imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -, (R) - This material has many physical properties. Its morphology, at room temperature or white to off-white crystalline powder, fine texture, like broken jade, dry to the touch, gently twisted in the hand, no sticky feeling.
    Looking at its solubility, in organic solvents such as ethanol and dichloromethane, it is like a river-sea stream, which can be well dissolved to form a uniform and transparent solution; however, in water, the solubility is poor, like water-repellent lotus leaves, difficult to blend.
    When it comes to the melting point, after rigorous determination, it is about a certain temperature range. This temperature is just like the node of its morphological transformation. At this temperature, the solid state gradually melts into a liquid state, just like ice and snow melting in spring.
    Its density also has a specific value, which gives it a unique "sense of weight" in the material world. In various mixed systems, according to this characteristic or fluctuation, or distribution, follow the laws of physics.
    In addition, its stability is good under common conditions, just like a stable person, not disturbed by external minor factors. However, in the case of extreme chemical environments such as strong acids and strong bases, the structure may change, such as when good wood encounters fire, it will inevitably be damaged. Such various physical properties are of critical significance in many fields such as chemical engineering and medicine, which affect its application and development.
    What are the main uses of 1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -, (R) -?
    This is (R) -4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole, and its use is quite important. This compound is used in the field of medicine, or can participate in the creation of drugs. Because of its specific molecular structure, or its role in specific physiological mechanisms of the human body, it can be used as an active ingredient to help develop drugs for the treatment of specific diseases, such as diseases related to specific receptor interactions.
    In the field of organic synthesis, it also has key value. Or as a key intermediate, through a series of chemical reactions, derived organic compounds with more complex and diverse structures, enrich the variety of organic compounds, and contribute to the development of organic synthesis chemistry. < Br >
    In the field of materials science, or due to its unique chemical properties, after appropriate treatment and modification, it is used to prepare materials with special properties, such as materials with adsorption or identification functions for specific substances, and it is used in separation, sensing and other fields.
    In addition, in scientific research, it also provides researchers with a good example of studying the relationship between molecular structure and properties. Through in-depth research, it can gain insight into how changes in molecular structure affect the physical, chemical and biological activities of compounds, and provide important theoretical basis and practical guidance for the design and development of subsequent new compounds.
    What are the synthesis methods of 1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -, (R) -?
    To prepare (R) -4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole, there are many ways to synthesize it.
    First, the corresponding halogen can be used for nucleophilic substitution reaction with imidazole. First, take the halogenated ethane derivative containing 2,3-dimethylphenyl, and its halogen atom activity needs to be suitable before it can react with imidazole in the presence of base. The base can capture the hydrogen of imidazole, enhance its nucleophilicity, and promote the smooth progress of nucleophilic substitution. When reacting, pay attention to the reaction temperature and time. If the temperature is too high or the time is too long, it may cause side reactions and cause impure products.
    Second, prepare by Grignard reagent method. The Grignard reagent is first prepared from 2,3-dimethyl bromobenzene, and then reacted with acetaldehyde to obtain the corresponding alcohol, and then converted into the target product through appropriate oxidation, substitution and other steps. In this process, the preparation conditions of Grignard reagent are strict, and it must be anhydrous and oxygen-free, and the subsequent reaction steps also need to be carefully controlled to ensure the yield and selectivity of each step.
    Third, it can also be achieved through the coupling reaction catalyzed by transition metals. Select a suitable transition metal catalyst, such as palladium catalyst, to couple a halide or boric acid derivative containing 2,3-dimethylphenyl group with a substrate containing imidazole structure. The advantage of this method is that the selectivity is good, but the catalyst cost is high, and the reaction conditions have a great impact on the catalyst activity. The reaction parameters, such as catalyst dosage, ligand selection, and the type and dosage of bases, need to be precisely adjusted to obtain satisfactory results.
    When synthesizing (R) -4- (1- (2,3-dimethylphenyl) ethyl) -1H-imidazole, regardless of the method used, attention should be paid to the optimization of the reaction conditions to improve the purity and yield of the product, while taking into account the cost and environmental factors, so that the synthesis method has practical application value.
    1H-Imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -, (R) - What is the price in the market?
    I don't know the price of "1H-imidazole, 4- (1- (2,3-dimethylphenyl) ethyl) -, (R) -" in the market. This is a fine chemical substance, and its price often varies for many reasons.
    First, the price of raw materials has a great impact. If the raw materials used to prepare this imidazole such as 2,3-dimethylphenyl are not easy to obtain, or their price fluctuates due to changes in season, origin, supply and demand, the price of this imidazole will also fluctuate. If the raw materials are abundant and the price is stable, the price of this imidazole may be slightly flat; if the raw materials are scarce and the price is high, the price must be high. < Br >
    Second, the preparation method is also the key. If the method is commonly available, the process is mature, the cost is controllable, and the price is close to the people; if the preparation requires special equipment, harsh conditions, or complex reactions in multiple steps, time-consuming and laborious, the cost is greatly increased, and its price in the market is high.
    Third, the supply and demand of the market also affect its price. If many industries want it, it is used in many fields such as medicine and chemical industry, and the demand is strong, but the supply is limited, the price will rise; if there is little demand and excess supply, the price may be lowered in order to seek sales.
    Fourth, the quality level is also related to the price. High purity, high quality, or for high-end scientific research, pharmaceutical manufacturing, the price must be higher than ordinary quality.
    Because there is no exact market information, it is difficult to determine the price. For details, when consulting chemical raw material suppliers, market surveys, or looking at the price of chemical product trading platforms, you can get a more accurate price.