1h Imidazole 4 1 2 3 Dimethylphenyl Ethyl Monohydrochloride
quinoline thiophene imidazole thiazole

1H-Imidazole, 4-1-(2,3-dimethylphenyl)ethyl-, monohydrochloride

    Specifications

    HS Code

    641264

    Chemical Formula C11H15N2.Cl
    Appearance Solid

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    General Information
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    Frequently Asked Questions

    As a leading 1H-Imidazole, 4-1-(2,3-dimethylphenyl)ethyl-, monohydrochloride supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical structure of 1H-Imidazole, 4-1- (2,3-dimethylphenyl) ethyl-, monohydrochloride?
    This is 1-H-imidazole, 4- [1- (2,3-dimethylphenyl) ethyl], a chemical compound of monohydrochloride. To clarify its chemical structure, it can be disassembled.
    The core of this compound is an imidazole ring, which is a five-membered nitrogen-containing heterocycle with unique electronic structure and chemical activity. At the 4th position of 1-H-imidazole, there is a substituent, namely [1 - (2,3-dimethylphenyl) ethyl]. In this substituent, the ethyl group is connected at one end to the 4th position of the imidazole ring and the other end to the 2,3-dimethylphenyl group. 2,3-Dimethylphenyl is a methyl group at the 2nd and 3rd positions of the benzene ring.
    is also known as "monohydrochloride", which means that this compound forms a salt with one molecule of hydrogen chloride. The hydrogen ion of hydrogen chloride combines with the basic nitrogen atom or other basic check points in the compound to form a salt structure. The formation of this salt can often change the physical and chemical properties of the compound, such as solubility and stability.
    From this perspective, the chemical structure of 1-H-imidazole, 4- [1 - (2,3-dimethylphenyl) ethyl], monohydrochloride, consists of an imidazole ring, a specific substituent and a hydrochloride salt moiety. The interaction of each moiety endows the compound with unique chemical properties and potential applications.
    What are the physical properties of 1H-Imidazole, 4-1- (2,3-dimethylphenyl) ethyl-, monohydrochloride?
    4- [1- (2,3-dimethylphenyl) ethyl] -1H-imidazole hydrochloride, this is an organic compound. It has some physical properties.
    Looking at its properties, under normal temperature and pressure, it is mostly in the state of white to quasi-white crystalline powder, which is conducive to storage and use. In terms of solubility, it has a certain solubility in water. This property is closely related to many chemical reactions. Because many reactions can occur smoothly in the liquid phase environment, it is easy to participate in various aqueous reactions if it is soluble.
    When it comes to the melting point, it is about a specific temperature range. The exact value of the melting point is of great significance for its identification and purity judgment. If the purity of the compound is high, the melting point is often close to the theoretical value, and the melting range is narrow; conversely, if the purity is poor, the melting point will shift and the melting range will become wider.
    In terms of stability, under normal storage conditions, if the environment is dry and the temperature is suitable, the compound can remain relatively stable. However, in case of high temperature, high humidity or specific chemical substances, chemical reactions may also occur, resulting in structural changes.
    Its density is also one of the important physical properties. The density value reflects the relationship between its mass and volume. In chemical production and related research, it is of guiding significance for the measurement and mixing of materials.
    These various physical properties play a crucial role in the application of this compound in chemical synthesis, drug development and other fields.
    What are the common uses of 1H-Imidazole, 4-1- (2,3-dimethylphenyl) ethyl-, monohydrochloride?
    1H-imidazole, 4- [1- (2,3-dimethylphenyl) ethyl], monohydrochloride, this is an organic compound. Its common uses are quite extensive.
    In the field of pharmaceutical research and development, this compound can be used as a key intermediate. Geinimidazole structures play an important role in many drug molecules, and by virtue of their unique chemical properties, they can interact with specific targets in organisms. For example, by modifying and modifying the structure of this compound, it can be used to develop drugs with specific pharmacological activities, or for the creation of antibacterial and anti-inflammatory drugs, and by precisely docking with pathogens or inflammation-related targets, it can exert therapeutic effects.
    In the field of materials science, it also has its uses. It may be able to participate in the synthesis of polymer materials, giving the material special properties by its own structure. For example, adding this compound in the preparation of some polymers can improve the thermal stability and mechanical properties of the material, making the material more suitable for high-end application scenarios, such as aerospace, electronic devices and other fields.
    In organic synthetic chemistry, it is often used as an important reagent. Because of its active check point in the structure, it can participate in a variety of organic reactions, such as nucleophilic substitution, cyclization reactions, etc., helping organic chemists to construct complex organic molecular structures, providing an effective way for the creation of new organic compounds, and greatly promoting the development of organic synthetic chemistry.
    What are the preparation methods of 1H-Imidazole, 4-1- (2,3-dimethylphenyl) ethyl-, monohydrochloride?
    The preparation method of 4- [1- (2,3-dimethylphenyl) ethyl] -1H-imidazole monohydrochloride, although it is not contained in Tiangong Kaiwu, it can be deduced according to the idea of ancient chemistry.
    To prepare this product, one of them can be a halogen containing 2,3-dimethylphenyl and an active intermediate containing an imidazole structure. Under a suitable base and solvent environment, nucleophilic substitution is performed. For example, with 2,3-dimethylbenzyl halide and imidazole, in a base such as potassium carbonate and a polar aprotic solvent such as N, N-dimethylformamide, heating and stirring, the halogen atom of benzyl halide is replaced by the nitrogen atom of imidazole to generate 4- [1- (2,3-dimethylphenyl) ethyl] -1H-imidazole. Thereafter, the resulting product is treated with a suitable solution of hydrochloric acid and adjusted to a suitable pH value to obtain 4- [1- (2,3-dimethylphenyl) ethyl] -1H-imidazole monohydrochloride.
    Second, an imidazole ring can be constructed first, and an imidazole ring structure can be formed by cyclization of an appropriate binary amine and a dicarbonyl compound under acid catalysis. For example, ethylenediamine and 2,3-dimethylphenylenedione are heated and refluxed under acetic acid catalysis to form an imidazole derivative. Subsequent to the reduction step, the carbonyl group is reduced to ethyl, and finally the target product is formed into a salt with hydrochloric acid.
    Third, with 2,3-dimethylstyrene as the starting material, it is first added with hydrogen halide to obtain a halophenethane derivative, and then reacted with an imidazole derivative to form an imidazole part of the target product, and finally a salt. During the reaction process, the purity of the raw materials, the reaction temperature, time, the proportion of reactants and the choice of solvent are all key factors, and fine regulation is required to obtain a higher yield and purity of 4- [1 - (2,3 - dimethylphenyl) ethyl] -1H - imidazole monohydrochloride.
    1H-Imidazole, 4-1- (2,3-dimethylphenyl) ethyl-, monohydrochloride What are the precautions during storage and transportation?
    1H-imidazole, 4- [1- (2,3-dimethylphenyl) ethyl], monohydrochloride, this is an organic compound. When storing and transporting, many points need to be paid attention to carefully.
    First pay attention to environmental conditions. It should be stored in a cool, dry and well-ventilated place. If the environment is humid, or the compound absorbs moisture, it will affect its purity and stability; if the temperature is too high, it may also trigger chemical reactions and cause deterioration. For example, if there is no cooling measure in the warehouse in summer, the compound may be in danger of decomposition.
    Furthermore, pay attention to the integrity of the package. Sealed packaging should be used to prevent contact with air, moisture, etc. Packaging is damaged, and external substances are easy to invade and contaminate compounds. If the package has small holes, water vapor infiltration, or agglomeration of the compound.
    When transporting, avoid violent vibration and collision. This compound may experience strong vibration due to structural characteristics, and internal chemical bonds may be affected, resulting in structural changes. Like transporting in bumpy road conditions, if the package has no buffering measures, the compound may be damaged due to collision.
    In addition, it is also necessary to pay attention to the isolation from other substances. Do not mix with oxidizing and reducing substances to avoid dangerous reactions. For example, coexist with strong oxidants, or cause serious consequences such as combustion and explosion.
    Operators also need to take good protection. When handling, appropriate protective equipment should be worn, such as gloves, goggles, etc., to avoid direct contact to prevent harm to the human body. If inadvertently touched, it should be dealt with in time according to relevant first aid measures.