1h Imidazole 2 Phenyl 1 Phenyl Methyl
quinoline thiophene imidazole thiazole

1H-Imidazole,2-phenyl-1-(phenyl methyl)-

    Specifications

    HS Code

    157808

    Chemical Formula C20H16N2
    Molecular Weight 284.36 g/mol
    Appearance Solid (usually white to off - white powder)
    Melting Point Typically in a certain range, e.g., around 140 - 145°C
    Boiling Point Under certain pressure conditions, a corresponding boiling point value
    Solubility In Water Low solubility in water
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane
    Density A specific density value (e.g., x g/cm³)
    Odor Odorless or with a faint characteristic odor
    Stability Stable under normal storage conditions, may react with strong oxidizing agents

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    General Information
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    Frequently Asked Questions

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    What is the chemical structure of 1H-Imidazole, 2-phenyl-1- (phenyl methyl) -?
    This is the chemical structure analysis of 2-phenyl-1- (phenylmethyl) -1H-imidazole. Looking at its name, it can be seen that this compound has a 1H-imidazole nucleus. 1H-imidazole is a five-membered heterocyclic compound containing dinitrogen atoms, with unique electron cloud distribution and reactivity.
    Its 2 positions are connected with phenyl, and the phenyl group is an aromatic ring composed of six carbon atoms. It has a highly conjugated system, which endows the compound with certain stability and special electronic effects. The 1-position (phenylmethyl), that is, benzyl, is composed of a phenyl ring connected to a methylene group. The introduction of benzyl groups may change the spatial structure and physicochemical properties of molecules.
    In the structure of this compound, the atoms are connected by covalent bonds. The bonding mode between atoms and the distribution of electron clouds determine its chemical activity and physical properties. The conjugation between aromatic rings may affect the optical properties and electron transfer ability of the compound. And the spatial resistance of different substituents may have a significant impact on the intermolecular interaction and reaction selectivity.
    From the perspective of overall structure, 2-phenyl-1- (phenylmethyl) -1H-imidazole combines the heterocyclic characteristics of imidazole, the aromaticity of phenyl and the structural characteristics of benzyl. Its unique structure may make it have potential application value in organic synthesis, medicinal chemistry and other fields. It can be used as a key intermediate for the construction of more complex compounds, or it can exhibit unique biological activities due to its special structure and properties.
    1H-Imidazole, 2-phenyl-1- (phenyl methyl) - What are the physical properties?
    2-Phenyl-1- (phenylmethyl) -1H-imidazole, this substance has various physical properties. Its shape or crystalline powder, white in color and pure in appearance. Under room temperature, the texture is stable, and if it is in a suitable environment, it can last for a long time without changing.
    When it comes to the melting point, it is about a specific range. This value is a key indicator to determine its purity and characteristics. The substance exhibits different degrees of solubility in organic solvents. In the case of alcohol solvents, it can be partially dissolved, like a fish entering water, and it is somewhat melted; in ether solvents, the solubility is slightly different, or slightly soluble, just like dust entering water, and it is difficult to find traces.
    Its density is also fixed. When weighing and blending, this data is very important, and it is related to the accuracy of the quantity. As for the boiling point, under a specific pressure environment, when it reaches a certain temperature, it will be boiling, just like water reaching 100 degrees Celsius and leaping.
    In addition, the refractive index of this substance presents a unique deflection angle when light penetrates, just like light twists and turns between prisms, which is unique. These physical properties are of key significance in many fields such as chemical industry and medicine. They are either the cornerstone of the synthesis of new products or the indicator of quality inspection.
    What are the common uses of 1H-Imidazole, 2-phenyl-1- (phenyl methyl) -?
    2-Phenyl-1- (phenylmethyl) -1H-imidazole, this is an organic compound. Its common use, in the ancient classical Chinese style of "Tiangong Kaiwu", may be expressed as follows:
    In the field of chemistry in this world, 2-phenyl-1- (phenylmethyl) -1H-imidazole is often a key raw material for organic synthesis. Because of its unique molecular structure, it has specific chemical activity and reactivity.
    First, in the field of pharmaceutical chemistry, it can be used as an intermediate for the synthesis of many drugs. Cover because of its structure can be combined with specific targets in the body, through ingenious chemical modification and transformation, or can be made into drugs with specific pharmacological activities to treat various diseases.
    Second, in the field of materials science, it is also highly valued. It can participate in the synthesis of polymer materials, through its polymerization with other monomers, endowing the material with unique physical and chemical properties, such as improving the stability and mechanical properties of the material.
    Third, in the field of catalysis, this compound may exhibit a certain catalytic activity. It can accelerate the reaction process, improve the reaction efficiency, and not be overconsumed in specific chemical reactions, just like the ancient craftsmen used exquisite skills to make everything go smoothly and get twice the result with half the effort.
    Fourth, in the field of electronic chemicals, or because of its electrical properties, it can be applied to the manufacture of electronic components, etc., to help optimize the performance of electronic equipment, just like adding bricks to the electronic world, making its operation more delicate.
    In short, although 2-phenyl-1- (phenylmethyl) -1H-imidazole is invisible and colorless, it plays a crucial role in many fields in this world, such as drugs, materials, catalysis, electronics, etc., like a skilled craftsman behind the scenes, silently promoting the progress of science and technology and industry.
    What are the preparation methods of 1H-Imidazole, 2-phenyl-1- (phenyl methyl) -
    To prepare 2-phenyl-1- (phenylmethyl) -1H-imidazole, the method is as follows:
    First, the intermediate product can be obtained by the condensation reaction of benzaldehyde and phenylacetonitrile under appropriate catalyst and conditions. Then the intermediate product is reacted with formamide at a suitable temperature and catalyst, and after cyclization and other steps, the target product 2-phenyl-1- (phenylmethyl) -1H-imidazole can be obtained.
    Second, acetophenone is used as the starting material, and the hydroxyaldehyde condensation reaction is first carried out with benzaldehyde under alkali catalysis to generate the corresponding unsaturated ketone. The unsaturated ketone is then reacted with cyanamide under specific conditions, and the imidazole compound can also be prepared through a series of changes such as cyclization and substitution.
    Third, benzyl chloride can also be reacted with imidazole in an alkaline environment to generate 1-benzyl imidazole. After that, 1-benzyl imidazole and phenylboronic acid are introduced into phenyl groups through a coupling reaction catalyzed by a transition metal catalyst to obtain 2-phenyl-1- (phenylmethyl) -1H-imidazole.
    Each method requires attention to the precise control of reaction conditions, such as temperature, pH, catalyst dosage, etc., in order to improve yield and purity and achieve the purpose of preparation.
    What are the properties of 1H-Imidazole, 2-phenyl-1- (phenyl methyl) - in chemical reactions?
    2-Phenyl-1- (phenylmethyl) -1H-imidazole is quite unique in chemical reactions. This compound has a specific structure, which is cleverly connected by phenyl, benzyl and imidazole rings. Its exquisite structure endows many unique reaction characteristics.
    First, because the imidazole ring has electron-rich properties, 2-phenyl-1- (phenylmethyl) -1H-imidazole can be used as a nucleophilic reagent. Under appropriate reaction conditions, it can attack electrophilic reagents, such as when it encounters halogenated hydrocarbons, the nitrogen atoms on the imidazole ring will attack the carbon atoms of halogenated hydrocarbons with their lone pairs of electrons, such as warriors holding swords, forming new carbon-nitrogen bonds and triggering nucleophilic substitution reactions. This is an important way to construct complex organic molecules.
    Second, the phenyl and benzyl parts in this compound increase the stability and hydrophobicity of the molecule due to the conjugation system of the benzene ring. In the aromatic electrophilic substitution reaction, this conjugated system can attract electrophilic reagents like a magnet, allowing the reaction to take place preferentially over specific locations of the benzene ring. When interacting with mixed acids such as nitric acid and sulfuric acid, the benzene ring will undergo nitrification reaction, and the substitution check point is precisely regulated by the original substituent localization effect.
    Furthermore, 2-phenyl-1- (phenylmethyl) -1H-imidazole may exhibit unique catalytic properties. In some organic synthesis reactions, the reactant molecules can be precisely positioned and activated by virtue of their structural characteristics, just like a brilliant conductor guiding an orchestra to play, reducing the activation energy of the reaction, improving the reaction rate and selectivity, and opening up new possibilities for the field of organic synthetic chemistry. In conclusion, 2-phenyl-1- (phenylmethyl) -1H-imidazole has many properties such as nucleophilicity, aromatic electrophilic substitution activity and potential catalysis in chemical reactions due to its unique structure, which is of great value in organic synthesis and other fields.