1h Imidazole 2 Chloromethyl 4 5 Dihydro Monohydrochloride
quinoline thiophene imidazole thiazole

1H-IMIDAZOLE, 2-(CHLOROMETHYL)-4,5-DIHYDRO-MONOHYDROCHLORIDE

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    HS Code

    897747

    Chemical Name 1H-Imidazole, 2-(chloromethyl)-4,5-dihydro-monohydrochloride

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    Frequently Asked Questions

    As a leading 1H-IMIDAZOLE, 2-(CHLOROMETHYL)-4,5-DIHYDRO-MONOHYDROCHLORIDE supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the chemical property of 1H-IMIDAZOLE 2- (CHLOROMETHYL) -4, 5-DIHYDRO-MONOHYDROCHLORIDE
    2 - (chloromethyl) -4,5 -dihydro-1H -imidazole, hydrochloride, this is an organic compound. It has unique chemical properties. It is mostly solid at room temperature and pressure, or white to light yellow crystalline powder. It can remain relatively stable in air, and may react chemically when encountering strong oxidizing agents, strong acids, and strong bases.
    From the perspective of physical properties, its solubility is quite critical. In polar solvents, such as water, methanol, and ethanol, it often exhibits a certain solubility. Due to the existence of groups in the molecule that can form hydrogen bonds with solvent molecules, which help it disperse in the solvent system. However, in non-polar solvents, such as n-hexane and benzene, the solubility is lower.
    In terms of chemical activity, chloromethyl groups in the molecule are abnormally active. Chlorine atoms have strong electron-absorbing properties, resulting in a decrease in the electron cloud density of the carbon site where they are located, making them vulnerable to attack by nucleophiles and triggering nucleophilic substitution reactions. For example, when catalyzed with alcohols, chlorine in chloromethyl groups can be replaced by alkoxy groups to form ether derivatives; when reacted with amines, nitrogen-containing substitution products can be formed, which is of great significance in organic synthesis for the construction of new carbon-nitrogen bonds.
    4,5-dihydroimidazole rings are also reactive. The lone pair electrons on the nitrogen atom in the ring can participate in a variety of reactions, such as the reaction with halogenated hydrocarbons, and the nitrogen atom can carry out nucleophilic attack on halogenated hydrocarbons to form quaternary ammonium salts. Moreover, due to the unsaturation of the ring, under suitable conditions, reactions such as hydroreduction and oxidation can occur, and then a variety of compounds can be derived, which opens many possibilities for the field of organic synthetic chemistry and has potential application value in drug development, materials science and other fields.
    What are the uses of 1H-IMIDAZOLE 2- (CHLOROMETHYL) -4, 5-DIHYDRO-MONOHYDROCHLORIDE
    2 - (chloromethyl) -4,5 -dihydro-1H-imidazole hydrochloride, this substance has a wide range of uses. In the field of medicinal chemistry, it is often a key intermediate for the synthesis of many drugs. Because its structure contains specific functional groups, it can be connected to other compounds through a series of chemical reactions to build complex molecules with specific pharmacological activities. For example, when developing antibacterial drugs, it can be used to participate in the reaction to construct drug molecular structures that inhibit or kill bacteria and help fight infectious diseases.
    In the field of materials science, it also has important uses. Can be used to prepare polymer materials with special functions. By introducing it into the polymer chain, the material is endowed with better stability and unique adsorption properties. For example, when preparing some adsorption resins, adding this compound can improve the adsorption capacity of the resin for specific substances, which can be used in the field of separation and purification, and can efficiently enrich the target components from the mixture.
    In organic synthesis chemistry, it is an extremely useful reagent. It can participate in a variety of organic reactions, such as nucleophilic substitution reactions, providing an effective way for the synthesis of novel organic compounds. Chemists can use it as a starting material to ingeniously construct organic molecules with different structures and functions by carefully designing reaction routes, expanding the variety and application range of organic compounds, and contributing to the development of organic synthesis chemistry.
    What is the synthesis method of 1H-IMIDAZOLE 2- (CHLOROMETHYL) -4, 5-DIHYDRO-MONOHYDROCHLORIDE
    The synthesis of 2- (chloromethyl) -4,5-dihydro-1H-imidazole hydrochloride is an important research in the field of chemical synthesis. The synthesis process probably requires multiple and delicate chemical reactions to achieve the formation of the target product.
    Initially, it is often necessary to select a suitable starting material, which should have the key functional groups that can be derived from the target molecular structure. Such as starting with nitrogen-containing heterocyclic compounds, or selecting substances with active haloalkyl groups, are all possible starting points.
    After that, the key reaction steps are carried out. Or involves nucleophilic substitution reactions, in which nucleophilic groups attack haloalkyl groups to form new carbon-nitrogen or carbon-other atomic chemical bonds to construct part of the imidazole ring structure. In this process, the control of reaction conditions is extremely important, such as reaction temperature, reaction time, solvent selection, etc., all have a significant impact on the process of the reaction and the purity of the product.
    If the temperature is too high, or side reactions occur frequently, the purity of the product decreases; if the temperature is too low, the reaction rate is slow and takes a long time. The polarity and solubility of the solvent also affect the activity and reaction path of the reactants.
    After the main structure of the imidazole ring is initially formed, a specific position needs to be modified to introduce chloromethyl. This step may require the use of halogenated reagents to achieve the precise introduction of chloromethyl under suitable catalytic conditions.
    Finally, after hydrochlorination treatment, the resulting product is converted into the form of hydrochloride. This process requires controlling the amount of hydrochloric acid and reaction conditions to ensure the formation of a single, pure 2- (chloromethyl) -4,5-dihydro-1H-imidazole hydrochloride.
    The entire synthesis process requires chemists to fine-tune each step of the reaction to obtain high-yield and high-purity target products. It is the crystallization of chemical synthesis skills and wisdom.
    1H-IMIDAZOLE, 2- (CHLOROMETHYL) -4, 5-DIHYDRO-MONOHYDROCHLORIDE What are the precautions in storage and transportation?
    2 - (chloromethyl) - 4,5 - dihydro - 1H - imidazole, monohydrochloride, this is a chemical substance. When storing and transporting, there are many things to pay attention to.
    First of all, this chemical should be stored in a cool, dry and well ventilated place. Because it may be sensitive to humidity and temperature, moisture can easily deteriorate, and the temperature is too high or cause chemical reactions. Therefore, the temperature and humidity of the warehouse should be properly regulated, the temperature should be maintained in a specific range, and the humidity should not be too high. And it must be kept away from fire and heat sources to prevent dangerous reactions due to heat. This chemical should also be stored separately from oxidizing agents, acids, alkalis, etc., and must not be mixed, as it may react violently with these substances, which may cause safety accidents.
    As for transportation, the handling process must be light and light, and must not be operated brutally to prevent damage to the packaging container. If the packaging is damaged, the chemical may be exposed, which may pose a threat to the environment and personal safety. Vehicles used in transportation must also be clean, dry, and equipped with corresponding protective equipment. During transportation, close attention should be paid to weather changes. In case of bad weather, such as heavy rain and high temperature, appropriate protective measures should be taken. In addition, transportation personnel should be well aware of the characteristics of the chemical and emergency treatment methods. In the event of an accident, they can respond quickly and correctly to reduce the harm.
    What is the market price of 1H-IMIDAZOLE 2- (CHLOROMETHYL) -4, 5-DIHYDRO-MONOHYDROCHLORIDE?
    I am inquiring about the market price of 2- (chloromethyl) -4,5-dihydro-1H-imidazole monohydrochloride. The price of this chemical substance varies for many reasons.
    First, the cost of preparation is the key. If the raw materials are easy to obtain and affordable, and the preparation method is simple and efficient, the cost will decrease and the price will also be lower. However, if the raw materials are rare, the preparation is complicated, and multiple processes and rare reagents are required, the cost will be high, and the price will also be high.
    Second, the market supply and demand situation is also heavy. If this substance is widely needed in the fields of medicine, chemical industry, etc., but the supply is limited, the price will rise. On the contrary, if the supply exceeds the demand, the merchant will sell the goods or reduce the price to promote.
    Third, the quality affects the price. High quality, less impurities, high purity, suitable for scientific research and high-end production, and the price is higher than that of ordinary quality.
    Fourth, manufacturers and brands have different prices. Well-known large factories, with their excellent reputation, technology and quality control, have high product prices; new factories or unknown ones are competing for the market, and the price may be favorable.
    To sum up, if you want to determine the price, you must consider the above things in detail. It is difficult to determine its exact price today, because the market is ever-changing and the price fluctuates. If you want to know the actual price, you can consult chemical raw material suppliers, chemical trading platforms, or people in the industry to obtain a near-real price.