1H-Imidazole,2-chloro-4-nitro-(9CI)

This is "2-cyanogen-4-amino-1H-pyrazole (9CI) ", and its chemical structure is as follows:
The pyrazole ring is a five-membered heterocyclic ring composed of two adjacent nitrogen atoms and three carbon atoms. For "2-cyanogen-4-amino-1H-pyrazole (9CI) ", on the basis of 1H-pyrazole, the cyano group (-CN) is connected at position 2, and the cyano group is connected by a three-bond between the carbon atom and the nitrogen atom; the amino group (-NH -2) is connected at position 4, and the amino group is connected by a nitrogen atom and two hydrogen atoms. In this structure, the pyrazole ring endows the compound with unique aromatic and heterocyclic chemical properties. The electron-absorbing properties of the cyano group affect the electron cloud distribution and reactivity of the molecule, and the amino group has a certain electron-giving ability and can participate in a variety of chemical reactions, such as nucleophilic substitution, reaction with acids to form salts, etc. These substituents interact with the pyrazole ring to jointly determine the chemical behavior and physical properties of the compound.

2 + -Deuterium-4-amino-1H-pyrazole (9CI) is an organic compound. Its physical properties are rich and diverse.
Looking at its appearance and properties, under room temperature and pressure, or white to light yellow crystalline powder, fine texture, this shape is easy to observe and follow-up operation.
On the melting point, it has been precisely determined to be between 150-155 ° C. When the temperature rises to this range, the compound gradually melts from a solid state to a liquid state. This melting point characteristic is of great significance for its purification, identification and application under specific conditions.
In terms of boiling point, in a normal pressure environment, the boiling point is about 350 ° C. The boiling point reflects the energy and conditions required for the compound to transform from liquid to gaseous state, and is of great reference value for its distillation separation, gas phase analysis and other operations.
Solubility is also an important property. It is slightly soluble in water, and the force between water molecules and the compound molecules is weak, resulting in limited solubility in water. However, in organic solvents such as ethanol and dichloromethane, it exhibits good solubility. This property provides the basis for its extraction, separation and chemical reaction solvent selection.
The density is about 1.3-1.4 g/cm ³, which is slightly higher than that of water, indicating that the mass of the compound is larger under the same volume, and it will affect the phase distribution in the mixed system. In terms of stability, 2 + -deuterium-4-amino-1H-pyrazole (9CI) is relatively stable under conventional environmental conditions and can be stored for a long time without significant chemical changes. However, in case of strong oxidizing agents, strong acids or strong bases, it is easy to chemically react and cause structural changes, so it is necessary to avoid such substances when storing and using.

2 + -Deuterium-4-amino-1H-pyrazole (9CI) is commonly used in the fields of medicine and chemical synthesis.
In pharmaceutical research and development, this compound is a key intermediate. Because of its unique structure, it can be reacted in a series of reactions and connected with other groups to build complex molecules with specific biological activities. For example, in the creation of some new antibacterial drugs, 2 + -deuterium-4-amino-1H-pyrazole (9CI) can be used as a starting material. By means of chemical synthesis, specific functional groups can be added to obtain drug molecules that have strong inhibitory or killing effects on specific bacteria. Due to the introduction of deuterium atoms, or the modification of drug metabolic properties, the action time in the body can be prolonged, the metabolic rate can be reduced, and the therapeutic effect can be improved.
In the field of chemical synthesis, it is also of great value. It can be used to prepare special functional materials. For example, when synthesizing polymer materials with unique optical and electrical properties, 2 + -deuterium-4-amino-1H-pyrazole (9CI) can participate in the copolymerization reaction, giving new properties to the material. And in organic synthesis chemistry, it serves as an important building block to help chemists build various complex organic structures, expand the variety and application range of organic compounds, and is of great significance for the development of new materials and product performance optimization in the chemical industry.

To prepare 2-cyano-4-amino-1H-pyrazole (9CI), the synthesis method is quite complicated, so let me go through them one by one.
One method can first take suitable starting materials and make them cyclize under specific reaction conditions. For example, select a nitrogen-containing compound and a carbohydrate with a specific substituent, in a suitable solvent, catalyze with a catalyst, control the temperature and reaction time, promote the formation of intramolecular rings, and initially construct the ring structure of pyrazole. This process requires fine control of the reaction conditions. Due to high or low temperature and improper amount of catalyst, the reaction can be biased to side reactions, affecting the yield and purity of the target product.
The second method can be modified by existing pyrazole derivatives. Find a pyrazole compound with a similar structure, use its activity check point, and introduce cyano and amino groups through substitution reaction. This requires activation of the pyrazole matrix first, so that the activity check point is easier to react with cyanide reagents and amination reagents. However, this process needs to pay attention to the selectivity of reagents and the sequence of reactions to avoid unnecessary side reactions.
The third method, or a multi-step series reaction strategy can be used. Using simple basic raw materials, the target molecular structure is gradually constructed in the same reaction system through a series of continuous reactions. Although this strategy can simplify the operation steps, it requires extremely high compatibility of reaction conditions. Each step of the reaction needs to be cleverly designed so that the product of the previous step can smoothly participate in the next reaction without being disturbed by other components in the system.
All these methods require the experimenter to have deep chemical knowledge and rich practical experience, careful operation, and careful regulation of reaction parameters. It is expected to efficiently synthesize 2-cyano- 4-amino-1H-pyrazole (9CI).

When storing and transporting 2 + -neon-4-amino-1H-pyrazole (9CI), many points need to be paid attention to.
When storing, the first environment. This substance should be placed in a cool, dry and well-ventilated place. Because neon is an inert gas, although its properties are stable, the amino and pyrazole structures in this compound may be affected by humidity and temperature. If the environment is humid, the amino group is easy to interact with water vapor, or cause material deterioration; if the temperature is too high, it may also cause changes in the structure of the pyrazole ring, affecting its chemical properties. Therefore, it is necessary to ensure that the temperature and humidity of the storage place are appropriate, and it is far away from heat and fire sources to avoid the risk of fire and explosion.
In addition, the choice of storage container is also critical. It is advisable to use a container with good corrosion resistance and sealing. Due to some groups in the compound or with certain activity, it comes into contact with the improper material container, or causes chemical reaction, which damages the container and causes material leakage. Such as metal containers or complexation reactions with certain active groups. At the same time, good sealing can prevent the material from contacting with the outside air components such as oxygen, carbon dioxide, etc., and avoid reactions such as oxidation and carbonation.
During transportation, safety protection is essential. It should be operated in accordance with the transportation specifications of hazardous chemicals to ensure that the transportation vehicle is well equipped and has fire protection, explosion-proof and leak-proof facilities. The handling process needs to be handled with care, because the compound structure contains pyrazole rings, or has a certain sensitivity, violent vibration, collision or structural damage, causing danger.
In addition, transportation documents are also essential. Information such as the name of the substance, characteristics, and emergency treatment methods should be clearly marked so that transportation personnel and emergency responders can respond quickly in emergencies and ensure the safety of personnel and the environment from pollution.