1H-imidazole-2-carbonitrile

1H-imidazole-2-formonitrile, this is an organic compound. It has many unique chemical properties.
In terms of its structure, it contains an imidazole ring and a formonitrile group. The imidazole ring is aromatic and has a unique electron cloud distribution, which makes the compound exhibit special reactivity. The presence of formonitrile groups adds to the diversity of its chemical properties.
In terms of reactivity, the formonitrile group can undergo a variety of reactions. It can be hydrolyzed to form carboxylic acids or amides. If under appropriate conditions, water is heated with an acid or base, and the nitrile group is hydrolyzed to form an amide first, and then further hydrolyzed to a carboxylic acid. For example, when heated in an acidic aqueous solution for a long time, 1H-imidazole-2-formonitrile is gradually converted into 1H-imidazole-2-carboxylic acid.
This compound can also participate in nucleophilic addition reactions. Because the carbon-nitrogen triple bond in the nitrile group is polar, the carbon atom is partially positively charged and vulnerable to nucleophilic attack. Nucleophilic reagents such as alcohols and amines can be added to them to form new nitrogen-containing or oxygen-containing derivatives.
Furthermore, due to the characteristics of the imidazole ring, 1H-imidazole-2-formonitrile can be used as a ligand to complex with metal ions. The nitrogen atom on the imidazole ring contains lone pairs of electrons, which can coordinate with metal ions to form stable metal complexes. It may have applications in catalysis, materials science and other fields.
Its physical properties are usually solid and have a certain melting point. Due to the presence of polar groups, it has a certain solubility in polar solvents such as ethanol and dimethyl sulfoxide, but it has a small solubility in non-polar solvents. In short, 1H-imidazole-2-formonitrile has a unique structure and various chemical properties, which is of great research and application value in organic synthesis and related fields.

1H-imidazole-2-formonitrile, this substance has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate. It is indispensable in many drug synthesis pathways. For example, some antibacterial drugs use it to build specific chemical structures to enhance antibacterial activity and drug stability, help resist pathogens from infecting the human body, and maintain health.
In the field of materials science, it also plays an important role. It can participate in the preparation of materials with unique functions, such as some materials with special adsorption properties or electrical properties. In the adsorption material, it can selectively adsorb specific substances, which can be used in water purification, gas separation, etc., to remove impurities and harmful gases in water, making the environment more suitable for survival.
In the field of organic synthesis, it is particularly useful. As an active reagent, it participates in a variety of organic reactions and builds complex organic molecular structures. Through delicate reaction design, it is used to synthesize organic compounds with special functions and structures, contributing to the development of organic synthetic chemistry, promoting the field to continue to expand and create more novel and practical organic compounds.

The synthesis method of 1H-imidazole-2-formonitrile has been around for a long time, and it has changed over the years. Today is your way.
First, it can be prepared by the substitution reaction of imidazole and halogenated acetonitrile. During this process, the two can react with an appropriate base as a catalyst, in a suitable solvent, and at a suitable temperature. If potassium carbonate is selected as a base, acetonitrile is used as a solvent, and heating and stirring, the nitrogen atom of imidazole can undergo nucleophilic substitution with the halogenated acetonitrile atom, and then 1H-imidazole-2-formonitrile is obtained. This method is easy to obtain raw materials, and the operation is relatively simple. However, the reaction conditions need to be carefully regulated, and the toxicity of halogenated acetonitrile also needs to be paid attention to, and careful protection must be taken during operation.
Second, nitrile acetamide and formamide are used as raw materials and can be obtained by cyclization reaction. Under the action of high temperature and catalyst, nitrile acetamide and formamide intramolecular atoms are rearranged and cyclized, and the final target product is obtained. Although this approach is not uncommon in raw materials, high temperature reaction requires quite high equipment requirements, and energy consumption is large. Energy costs and product yields must be weighed.
Third, it is synthesized from 2-halo imidazole and metal cyanide through nucleophilic substitution The cyanyl group in the metal cyanide can replace the halogen atom of the halogenated imidazole to obtain 1H-imidazole-2-formonitrile. In this process, the metal cyanide is very toxic, and care must be taken during operation. The reaction needs to be carried out in an anhydrous and anaerobic environment, and the reaction conditions are strict. However, if it can be operated carefully, the yield is also considerable.
These are all common synthesis methods of 1H-imidazole-2-formonitrile, each with its own advantages and disadvantages. Careful choices need to be made according to many factors such as actual demand, raw material availability, cost considerations, and equipment conditions.

I look at the price range of "1H-imidazole-2-formonitrile" you are inquiring about in the market, which is a matter of market change. However, the market situation is complex, and the price is uncertain, which is influenced by various factors.
In terms of supply, if the origin is abundant and the supply is sufficient, the price may tend to be easy; if the supply is scarce and the supply is in short supply, the price will rise. Furthermore, the difference in quality is also the key. The price of the superior product should be high; the second, the price may be slightly lower.
And the market demand also affects its price. If there is a strong demand for this product in various industries and it is used in pharmaceuticals, chemicals, etc., the price will be high; if the demand is low, the price will drop.
As for the exact price range, it is difficult to determine. In my opinion, it may be between a few yuan and a few tens of yuan per gram. However, this is only an idea, and the market situation changes like the situation. The actual price must also be carefully inspected by the merchants in various cities, and the market of chemical materials and the platform of online trading can be known. It is necessary to study the market carefully to obtain an accurate number.

1H-imidazole-2-formonitrile is also a chemical substance. Its storage conditions are quite critical, related to its quality and stability.
This substance should be stored in a cool and dry place. A cool place can avoid the harm of high temperature. High temperature can accelerate its chemical reaction, or cause structural changes or properties to change. A dry environment is also indispensable, because moisture can cause many problems, such as hydrolysis reactions, resulting in deterioration of the substance.
Furthermore, the storage place should be well ventilated. With good ventilation, harmful gases can disperse and will not accumulate and cause danger. And it needs to be kept away from fire and heat sources. Open flames and hot topics can cause it to burn or even explode, which is really a big problem. < Br >
And should be stored separately from oxidizing agents, acids, bases, etc. If these numbers coexist with 1H-imidazole-2-formonitrile, they are prone to chemical reactions or unpredictable changes.
In terms of packaging, attention should also be paid. Sealed packaging should be used to ensure that outside air, moisture, etc. are not invaded to maintain their original characteristics. And the storage area should be equipped with suitable materials to deal with possible leakage.
In short, proper storage of 1H-imidazole-2-formonitrile, in accordance with the above conditions of cool, dry, ventilated, isolated and suitable packaging, can keep it in good condition for a long time, so that it can play its due role when used.