1h Imidazole 2 5 Dibromo 4 Nitro
quinoline thiophene imidazole thiazole

1H-Imidazole, 2,5-dibromo-4-nitro-

    Specifications

    HS Code

    282512

    Name 2,5-dibromo-4-nitro-1H-imidazole
    Molecular Formula C3HBr2N3O2
    Molecular Weight 267.86 g/mol
    Appearance Solid
    Color Off - white to yellowish
    Melting Point 198 - 202 °C
    Solubility In Water Low solubility
    Solubility In Organic Solvents Soluble in some polar organic solvents like DMSO
    Stability Stable under normal conditions, but may react with strong oxidizing agents
    Hazard Class Irritant, may cause skin, eye and respiratory irritation

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    General Information
    Where to Buy 1H-Imidazole, 2,5-dibromo-4-nitro- in China?
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    Frequently Asked Questions

    As a leading 1H-Imidazole, 2,5-dibromo-4-nitro- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 1H-Imidazole, 2,5-dibromo-4-nitro-?
    2,5-Dibromo-4-nitro-1H-imidazole, the chemical properties of this substance are quite unique. Its appearance is often in a specific form, mostly solid, but also subject to preparation and environmental conditions.
    When it comes to physical properties, this substance may have a certain color or be a colorless to light yellow solid at room temperature and pressure. Its melting point and boiling point are both key characteristics, and the melting point may be in a specific temperature range. This value is extremely important for identification and purification; the boiling point also depends on its molecular structure and intermolecular forces, and it will undergo gasification transformation under specific pressure.
    From the perspective of chemical properties, the bromine atom, nitro and imidazole ring structures contained in 2,5-dibromo-4-nitro-1H-imidazole give them diverse reactivity. Nitro is a strong electron-absorbing group, which reduces the electron cloud density of the imidazole ring, making the electrophilic substitution reaction on the ring more likely to occur at a specific location. Bromine atoms can participate in a variety of substitution reactions, such as nucleophilic substitution, which can be replaced by other nucleophilic reagents to form new compounds.
    It is widely used in the field of organic synthesis and is often used as a key intermediate to construct more complex organic molecular structures. In many chemical reaction systems, due to its unique chemical properties, it can guide the reaction to proceed according to a specific path, providing the possibility for the synthesis of organic compounds with specific functions and structures.
    Because it contains nitro and bromine atoms, it may exhibit certain stability under certain conditions, but under the action of specific reagents and reaction conditions, it can actively participate in various chemical transformations, which is an important substance that cannot be ignored in chemical research and organic synthesis.
    What are the main uses of 1H-Imidazole, 2,5-dibromo-4-nitro-?
    2,5-Dibromo-4-nitro-1H-imidazole, this substance has a wide range of uses. In the field of medicine, it is often used as a key intermediate for the synthesis of drugs with specific biological activities. Due to its unique structure, it can participate in many chemical reactions. Through chemical modification, compounds with different pharmacological properties can be obtained, or with antibacterial, antiviral, antitumor and other effects, opening up new paths for pharmaceutical research and development.
    In the field of materials science, it has also emerged. It can be integrated into polymer materials through special processes to endow materials with unique properties, such as improving material stability, heat resistance, or making them have special optical and electrical properties, so that they can be used in advanced electronic devices, optical materials and other cutting-edge fields.
    In the field of organic synthesis chemistry, it is an important cornerstone. With its activity of bromine atoms and nitro groups, it can trigger various nucleophilic substitution, electrophilic addition and other reactions. Organic chemists use this to construct complex organic molecular structures, expand the types and properties of organic compounds, and promote the continuous development of organic synthesis chemistry, laying the foundation for the creation of new materials and the preparation of fine chemicals.
    What is the synthesis method of 1H-Imidazole, 2,5-dibromo-4-nitro-?
    To prepare 2,5-dibromo-4-nitro-1H-imidazole, the method is as follows:
    Take the imidazole as the base first, because its structure contains an electron-rich five-membered heterocycle, which is active and reactive. Place the imidazole in an appropriate reaction vessel, first cool it at low temperature, usually controlled at 0-5 ° C, this is to make the reaction smooth and controllable.
    Next, slowly drop the brominating reagent, such as a solution of liquid bromine and an appropriate solvent, bromine is an electrophilic reagent in this reaction. When adding dropwise, pay close attention to the temperature of the reaction system to prevent overreaction. Bromine attacks the imidazole ring, and after electrophilic substitution, bromine atoms are introduced at the 2nd and 5th positions of the imidazole ring to obtain 2,5-dibromimidazole intermediates.
    Then mix this intermediate with appropriate nitrifying reagents, such as concentrated nitric acid mixed with concentrated sulfuric acid. This step also requires temperature control, mostly at low temperature, about 5-10 ° C. Nitrate ions in mixed acids generate nitroyl positive ions under the action of concentrated sulfuric acid, which is a strong electrophilic reagent. Attack the 2,5-dibromimidazole ring and introduce nitro at the 4th position. After a series of reactions, 2,5-dibromo-4-nitro-1H-imidazole is finally obtained.
    After the reaction is completed, a post-treatment process is required. Extraction with appropriate solvent to remove unreacted raw materials and by-products, and then purification by column chromatography or recrystallization to obtain pure 2,5-dibromo-4-nitro-1H-imidazole products.
    In which fields is 1H-Imidazole, 2,5-dibromo-4-nitro-used?
    2,5-Dibromo-4-nitro-1H-imidazole is useful in many fields. In the field of pharmaceutical research and development, it is often a key intermediate. Medical pharmaceuticals, based on it, can synthesize drugs with unique effects. Because of its special structure, it can interact with many biomolecules in the body, or can regulate physiological functions and treat diseases.
    In the field of materials science, it also has extraordinary performance. This substance can be integrated into new materials through specific processes. The material is given unique chemical and physical properties, such as enhancing the stability of the material and changing its optical properties. With this, craftsmen can create new materials with excellent performance to suit the needs of different scenarios.
    In the world of organic synthesis, it plays an important role. The way of synthesis requires the coordination of various reagents, and 2,5-dibromo-4-nitro-1H-imidazole is often a wonder in the hands of organic chemists. It can be used to realize the construction of complex organic molecules, reach a unique reaction path, open up new paths for the field of organic synthesis, and help create more novel and practical organic compounds.
    What is the market outlook for 1H-Imidazole, 2,5-dibromo-4-nitro-?
    2,5-Dibromo-4-nitro-1H-imidazole is quite fascinating to explore in terms of market prospects. Looking at the field of chemical trade today, this compound has emerged in various fields due to its unique chemical structure and characteristics, which has attracted market attention.
    In the process of pharmaceutical research and development, it may be a key intermediate for the creation of new drugs. The presence of bromine and nitro groups in its structure endows the molecule with different reactivity and pharmacological potential, which may pave a new path for the development of new drugs against difficult diseases, so the demand for it in the pharmaceutical industry is gradually rising.
    In the field of materials science, 2,5-dibromo-4-nitro-1H-imidazole also shines. After clever chemical modification and synthesis, new materials with specific properties may be prepared, such as optoelectronic materials, polymer materials, etc. These materials are widely used in electronic equipment, optical instruments and other industries, and there is also a strong demand for them in the field of materials.
    However, looking at its market supply, there are also some variables. On the one hand, the process or complexity and cost of preparing this compound. The control of raw materials and reaction conditions required in the synthesis process has a profound impact on production efficiency and cost. If the process is not optimized and refined, the output may be limited, and the supply will be difficult to keep up with the growth of demand.
    On the other hand, the market competition situation also affects its prospects. With the gradual emergence of its application potential, many chemical companies may compete to get involved in R & D and production. Although this can promote the progress of industry technology, it may also cause the worry of oversupply in the market and cause price fluctuations.
    Overall, 2,5-dibromo-4-nitro-1H-imidazole is in the market prospect, with both opportunities and challenges. If it can overcome the problem of preparation process and deal with market competition reasonably, it will be able to open up a wide range of fields in medicine, materials and other fields and achieve extraordinary business.