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What is the chemical structure of 1H-imidazole, 2- [1- (2,6-dichlorophenoxy) ethyl] -4,5-dihydro-, hydrochloride (1:1)
This is an investigation into the chemical structure of 2 - [1 - (2,6 - dichlorophenoxy) ethyl] -4,5 - dihydro - 1H - imidazole hydrochloride (1:1).
For details, name it first. "2 - [1 - (2,6 - dichlorophenoxy) ethyl]", this part shows that at the second position of the imidazole ring, a substituent containing 1 - (2,6 - dichlorophenoxy) ethyl is connected. Among them, 2,6-dichlorophenoxy, that is, the 2nd and 6th positions of the benzene ring are substituted by chlorine atoms, and are connected to the oxygen atom to form a phenoxy group, which is then connected to the carbon of the 1st position of the ethyl group.
"4,5-dihydro-1H-imidazole", indicating that the double bonds of the imidazole ring are hydrogenated and saturated to form a dihydro-imidazole structure. And "hydrochloride salt (1:1) " means that the organic matter and hydrochloric acid form a salt in a 1:1 ratio, that is, the nitrogen atom on the imidazole ring binds to a hydrogen ion and forms a salt with the chloride ion.
In summary, the chemical structure of this compound, with a dihydroimidazole ring as the core, is connected to a 1- (2,6-dichlorophenoxy) ethyl substituent at 2 positions, and forms a hydrochloride salt. Its unique structure and interrelated parts determine the unique chemical and physical properties of the compound.
What are the main uses of 1H-imidazole, 2- [1- (2,6-dichlorophenoxy) ethyl] -4,5-dihydro-, hydrochloride (1:1)
2 - [1 - (2,6 - dichlorophenoxy) ethyl] - 4,5 - dihydro - 1H - imidazole hydrochloride (1:1), this is an organic compound. It has a wide range of uses and is often used as an intermediate in drug synthesis in the field of medicine. Due to its specific chemical structure, it can participate in the construction of many complex drug molecules, assisting in the development of antibacterial, antiviral and other drugs. In the field of pesticides, it also has important applications, or can be used to create new pesticides. With its unique activity, it can inhibit and kill pests and bacteria, and improve crop yield and quality. In addition, in the field of materials science, it may be used as a key raw material for the synthesis of functional materials, giving materials specific properties, such as improving material stability, reactivity, etc. Due to the structural properties of this compound, it can play a unique role in the above fields, becoming an indispensable substance in many research and production processes, and is of great significance for promoting the development of industries such as medicine, agriculture, and materials.
What are the physical properties of 1H-imidazole, 2- [1- (2,6-dichlorophenoxy) ethyl] -4,5-dihydro-, hydrochloride (1:1)
2 - [1 - (2,6 - dichlorophenoxy) ethyl] - 4,5 - dihydro - 1H - imidazole hydrochloride (1:1), the physical properties of this substance are quite important, related to its application in many fields.
Looking at its morphology, under room temperature and pressure, or white to white crystalline powder, fine and uniform, like snow falling in the early winter, pure texture. Its particle size distribution is relatively concentrated, with an average particle size of about [X] microns, which makes it exhibit good uniformity during specific process operations such as mixing and dispersion, and is convenient for subsequent processing.
As for the melting point, after precise determination, it is about [specific temperature range], and this melting point characteristic is indicative of its phase transition during heating. When heated, when the temperature gradually rises to the melting point range, the intermolecular force weakens, the lattice structure begins to loosen, and the substance gradually melts from the solid state to the liquid state. This process is smooth and has a specific temperature range, showing its relatively stable thermal stability.
In terms of solubility, this substance exhibits a certain solubility in organic solvents such as ethanol and acetone, just like fish get water, and can be uniformly dispersed to form a homogeneous solution. In water, it also has a certain solubility, but the solubility varies with temperature. When the temperature increases, the solubility tends to increase. This property may be related to the effect of temperature on the interaction force between water molecules and the molecules of the substance.
In addition, its density is also one of the important physical properties, about [specific value] g/cm ³. Compared with common organic solvents and water, it has unique specific gravity characteristics, and may play a key role in liquid-liquid separation and other operations. At the same time, the substance has a certain sensitivity to light and humidity. In the environment of too strong light or too high humidity, it may decompose slightly or change its properties. Therefore, it needs to be stored in a dry and dark place, so as to maintain the stability of its physical properties.
What is the synthesis method of 1H-imidazole, 2- [1- (2,6-dichlorophenoxy) ethyl] -4,5-dihydro-, hydrochloride (1:1)
Now there are 2 - [1 - (2,6 - dichlorophenoxy) ethyl] -4,5 - dihydro - 1H - imidazole hydrochloride (1:1). To make it, the method is as follows.
First take an appropriate amount of 2,6 - dichlorophenol, put it in a clean reactor, and adjust its pH with an appropriate amount of alkali to make it alkaline. Then slowly add halogenated ethane dropwise, during which the temperature should be controlled in a suitable range, and constantly stir to promote its full reaction, to obtain 1 - (2,6 - dichlorophenoxy) ethane. < Br >
Another appropriate amount of glyoxal, formaldehyde and ammonium salts are taken in another reaction vessel, catalyzed by a specific catalyst, and cyclized under suitable temperature and pressure conditions to generate 4,5-dihydro-1H-imidazole.
Then the obtained 1 - (2,6 - dichlorophenoxy) ethane and 4,5 - dihydro - 1H - imidazole were placed in the same reaction system, an appropriate amount of acid binding agent was added, and under heating and stirring, the two were promoted to carry out a substitution reaction to obtain 2 - [1 - (2,6 - dichlorophenoxy) ethyl] -4,5 - dihydro - 1H - imidazole.
Finally, the obtained 2- [1- (2,6-dichlorophenoxy) ethyl] -4,5-dihydro-1H-imidazole is introduced into hydrogen chloride gas, and the reaction conditions are controlled to make it a salt, which is to obtain 2- [1- (2,6-dichlorophenoxy) ethyl] -4,5-dihydro-1H-imidazole hydrochloride (1:1). After the reaction is completed, the pure product can be obtained through separation, purification and other operations.
1H-imidazole, 2- [1- (2,6-dichlorophenoxy) ethyl] -4,5-dihydro-, hydrochloride (1:1) What are the precautions during use
2 - [1 - (2,6 - dichlorophenoxy) ethyl] - 4,5 - dihydro - 1H - imidazole hydrochloride (1:1) is a special chemical substance, and there are many things to pay attention to during use.
First of all, pay attention to its toxicity. This chemical may have certain toxicity, and should not be negligent when exposed. When operating, appropriate protective equipment, such as protective gloves, goggles and lab clothes, must be worn to prevent direct contact with the skin and eyes. If it touches the skin accidentally, rinse with plenty of water immediately; if it enters the eye, rinse quickly and seek medical treatment.
Furthermore, pay attention to its chemical activity. Due to its special structure, chemical properties or relatively active, it is easy to react with other substances. When storing, it must be separated from oxidizing and reducing substances, acids and bases, etc., to prevent accidental reactions. During the mixing process, it is necessary to add solvents and solutes in the correct order, and pay attention to the temperature and humidity of the operating environment, because it may affect the reaction process.
At the same time, the stability of this substance cannot be ignored. Temperature and light have a great impact on its stability. Under high temperature and strong light environment, it may cause decomposition and deterioration, which will affect the use effect. Therefore, it should be stored in a cool, dry and dark place.
When using this substance for experiments, the cleanliness and dryness of the experimental equipment are essential. Residual impurities or reactions with the substance interfere with the experimental results. After each use, the equipment needs to be properly cleaned.
In addition, it is also crucial to strictly follow the established operating procedures. Before operation, be familiar with the operation process and precautions, and do not change the operation steps at will to prevent danger. After the experiment, the remaining substances and waste should be disposed of in accordance with regulations and should not be discarded at will to avoid polluting the environment.