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1H-Imidazole-1-ethanol, what is the main use of 2-methyl-
1H-imidazole-1-ethanol, 2-methyl-this substance has a wide range of uses. In the field of medicine, it can be used as a key intermediate to help synthesize many drugs. Because it has a specific chemical structure and activity, it can participate in the construction of drug molecules, affect the pharmacological properties of drugs, or enhance the efficacy, or improve the pharmacokinetic properties.
In the chemical industry, it is also an important raw material. It can be used to prepare various fine chemicals, such as some additives with special properties. Added to specific products, it can improve product performance, such as enhancing product stability and improving processing performance.
In addition, in the field of materials science, it has also emerged. With its unique chemical properties, it can be used to prepare new materials and endow them with special properties, such as improving the adsorption and conductivity of materials. In short, 1H-imidazole-1-ethanol, 2-methyl-is of great value in many fields and plays an indispensable role in promoting the development of related industries.
1H-Imidazole-1-ethanol, what are the physical properties of 2-methyl-
2-Methyl-1H-imidazole-1-ethanol, this is an organic compound. According to its physical properties, at room temperature, it is mostly colorless to light yellow liquid, and its properties are stable. It has a specific odor, or is caused by the imidazole ring and ethanol group contained in the molecular structure.
Its boiling point is related to the intermolecular force. Due to the action of hydrogen bonds in the molecule, its boiling point may be in a relatively high range, about 200-300 ° C. This compound exhibits good solubility in organic solvents, such as ethanol, acetone, etc. Due to the principle of similar miscibility, the polar groups in its structure are in agreement with the polarity of the organic solvent. < Br >
And its melting point, in view of the orderly arrangement and interaction of molecular structures, may be relatively low, between -10 ° C and 10 ° C. The density may be similar to that of water, and its refractive index is also characteristic, reflecting the refractive ability of molecules to light, or between 1.45 and 1.55.
These various physical properties are closely related to the molecular structure of the compound, which is of great significance for its application in chemical, pharmaceutical and other fields. It is of key guiding value for the control of reaction conditions and the operation of separation and purification.
1H-Imidazole-1-ethanol, is 2-methyl- chemically stable?
The chemical properties of 2-methyl-1H-imidazole-1-ethanol are still stable. This compound contains specific functional groups, and under suitable conditions, it can retain its inherent structure and properties.
Looking at its structure, the imidazole ring is aromatic, which can endow the compound with certain chemical stability. The methyl group is attached to the imidazole ring, because the methyl group is the power supply radical, or has an impact on the electron cloud distribution of the imidazole ring, however, the structure does not change significantly, but the molecular stability is slightly increased.
And the ethanol group is connected to the imidazole ring, which also contributes to the stability of the substance by virtue of its ability to form hydrogen bonds with other molecules, or to enhance intermolecular forces under specific environments.
Under normal conditions, in the absence of special reagents or extreme environments, the chemical bonds of 2-methyl-1H-imidazole-1-ethanol can remain stable and do not easily break or rearrange. In case of extreme conditions such as strong oxidants, strong acids and bases or high temperatures, its chemical stability may be challenged, triggering reactions such as oxidation and hydrolysis, resulting in changes in molecular structure.
In short, under normal conditions, the chemical properties of 2-methyl-1H-imidazole-1-ethanol are relatively stable, but under special conditions, it is necessary to carefully consider its possible chemical changes.
1H-Imidazole-1-ethanol, what are the synthesis methods of 2-methyl-
To prepare 1H-imidazole-1-ethanol, 2-methyl-there are two methods. First, use 2-methylimidazole and ethylene oxide as the starting materials. First, take an appropriate amount of 2-methylimidazole and place it in a clean reactor, the temperature is controlled in a specific range, usually 30 to 50 degrees Celsius. Then slowly introduce ethylene oxide gas, and in this process, continue to stir to make full contact between the two. The mechanism of this reaction is that ethylene oxide is ring-opening, connected to the nitrogen atom of 2-methylimidazole, and then the target product is formed. After the reaction is completed, the product is purified by vacuum distillation and recrystallization. < Br >
Second, use 2-methyl-1- (2-chloroethyl) imidazole as raw material. Take this raw material and place it in a solution containing alkali, such as sodium hydroxide or potassium hydroxide. The temperature is controlled at 60 to 80 degrees Celsius, and the nucleophilic substitution reaction is carried out. The chlorine atom of 2-methyl-1- (2-chloroethyl) imidazole is replaced by a hydroxyl group by a base, and then 1H-imidazole-1-ethanol, 2-methyl- is obtained. After the reaction is completed, the pure product can be obtained through extraction, drying, distillation and other processes. The two methods have their own advantages and disadvantages. The former has mild reaction conditions, but ethylene oxide gas is flammable and explosive, so the operation needs to be careful. The latter raw materials are easier to obtain and the reaction is easier to control, but the purification steps are slightly more complicated.
1H-Imidazole-1-ethanol, what is the price range of 2-methyl in the market?
In today's world, the market is complex, the price of goods varies from time to time, from place to place, and also varies with supply and demand, and the quality is different. However, it is not easy to know the price range of 1H-imidazole-1-ethanol, 2-methyl-this product in the market.
Because of its wide application field, it is involved in many industries such as chemical industry and medicine. Different uses have different quality requirements and prices. In the chemical field, those who are used as raw materials, or due to the huge amount, have a slightly slower quality requirements, and their price may be relatively easy; if in pharmaceutical research and development, the quality control of purity and impurity content is strict, and the price may be high.
And the economic conditions, logistics costs, and market competition situation of different regions are different. Prosperous cities, with strong demand, but the supply is sufficient, the competition is fierce, and the price may be stable and decline; remote places, logistics is inconvenient, the supply is scarce, and the price may be high.
Looking at the market, there is no conclusive market. If you want to know the details, you should consult chemical raw material suppliers, pharmaceutical intermediates distributors, or at professional chemical trading platforms, industry exhibitions, etc., inquire from many parties, compare the quotations of various companies, and examine the quality differences in detail, in order to obtain the approximate price range, which is almost correct.