1H-Imidazole-1-aceticacid,4-methyl-,methylester(9CI)

This is the chemical structure analysis of methyl 4-methyl-1H-imidazole-1-acetate (9CI). Looking at its name, its structure can be inferred gradually. "1H-imidazole-1-acetic acid" is based on the imidazole ring, and the first position is connected to the acetic acid, that is, the carbon atom of the imidazole ring is connected to the carboxyl carbon atom of the acetic acid. "4-methyl" indicates that the carbon atom of the imidazole ring is connected with a methyl group. "Methyl ester" means that the carboxyl group of acetic acid is esterified with methanol to form a methyl ester group. In summary, the chemical structure of the compound is: 1 position of imidazole ring is connected with methyl acetate group, and 4 position of imidazole ring has methyl substitution. So, the chemical structure of this compound is clear.

1H-imidazole-1-acetic acid, 4-methyl-, methyl ester (9CI), this compound has a wide range of uses. In the field of medicinal chemistry, it is often used as a key intermediate to assist in drug synthesis. Due to its unique chemical structure, it can participate in a variety of reactions. After modification and modification, it fits with specific biological targets and is used to develop innovative drugs for the treatment of various diseases.
In the field of materials science, it can contribute to the synthesis of special materials. It can be integrated into polymer materials through polymerization or cross-linking reactions to endow materials with special properties such as good stability and biocompatibility, making it useful in biomedical materials, high-performance composites, etc.
In the field of organic synthetic chemistry, it is a powerful cornerstone for the construction of complex organic molecules. With its activity check point, with the help of various organic reactions, such as nucleophilic substitution, cyclization reaction, etc., to build organic compounds with specific structures and functions, paving the way for the synthesis of novel organic molecules.
In biochemical research, it may serve as a mimic of bioactive molecules, helping to explore complex biochemical processes in organisms and protein-ligand interaction mechanisms, providing a powerful tool for revealing the mysteries of life.
In a word, 1H-imidazole-1-acetic acid, 4-methyl-, methyl ester (9CI) is of great value in many scientific fields and is an important chemical substance that promotes the development of related fields.

The physical properties of 1H-imidazole-1-acetic acid, 4-methyl-, methyl ester (9CI) are crucial for many practical applications. Its properties are either solid or liquid, which is the first sign. Looking at its color, it is colorless and transparent, or has a slight color. The difference in color is often related to impurities and molecular structures. Its melting point and boiling point are also important properties. For melting point, the temperature at which a substance changes from solid to liquid state, and the boiling point is the temperature at which the liquid state changes to gas state. The two reflect the strength of intermolecular forces.
Solubility cannot be ignored. The dissolution in water and organic solvents is different, or soluble in polar organic solvents, or insoluble in water, which is related to factors such as molecular polarity and hydrogen bonds. Density is related to the mass per unit volume, and has an impact on storage and transportation.
Furthermore, the smell may be characteristic, which originates from specific groups in the molecular structure. Volatility is related to the difficulty of changing from liquid to gaseous at room temperature and pressure. The above physical properties are of great guiding significance for their extraction, separation, storage, and use in the fields of chemical industry, medicine, etc., and are indeed key elements that cannot be ignored.

The synthesis of 4-methyl-1H-imidazole-1-acetate methyl ester (9CI) is involved in the field of chemical preparation. The methods have various advantages and disadvantages, depending on the purity, yield and cost of the desired product.
First, it can be obtained by esterification of 4-methyl-1H-imidazole-1-acetic acid and methanol under the action of a catalyst. In this reaction, common catalysts such as sulfuric acid and p-toluenesulfonic acid are used. Taking sulfuric acid as an example, its catalytic activity is high and the reaction rate is fast. However, sulfuric acid is highly corrosive, requires strict equipment, and the follow-up treatment is complicated. Neutralization and washing are required to remove catalyst residues. For specific operation, 4-methyl-1H-imidazole-1-acetic acid and methanol are placed in a reactor in a certain proportion, an appropriate amount of sulfuric acid is added, and the temperature is controlled and stirred. After the reaction is completed, the product is purified through neutralization, separation, distillation and other steps.
Second, the acyl chloride method is also possible. First, 4-methyl-1H-imidazole-1-acetic acid is converted into acyl chloride, and chlorination reagents such as dichlorosulfoxide and phosphorus trichloride are commonly used. Taking dichlorosulfoxide as an example, it reacts with acid to form an acid chloride, and at the same time produces sulfur dioxide and hydrogen chloride gas, which is easy to separate. The obtained acid chloride reacts with methanol to obtain the target product. In this process, the acid chloride has high activity, mild reaction conditions, and good product purity. However, dichlorosulfoxide is irritating and corrosive, and the operation needs to be well ventilated, and attention should be paid to tail gas treatment.
Third, the transesterification method can also be synthesized. Transesterification is carried out with 4-methyl-1H-imidazole-1-ethyl acetate and methanol under the action of catalysts. The catalysts used can be alkali metal alkoxides, titanates, etc. The advantage of this method is that the raw materials are easy to obtain and the reaction conditions are However, the problem of reaction equilibrium needs to be paid attention to, and it is often necessary to continuously remove one of the products to move the reaction in the direction of generating the target product to improve the yield.
There are various methods for synthesizing 4-methyl-1H-imidazole-1-methyl acetate. In practical applications, it is necessary to comprehensively consider the cost of raw materials, reaction conditions, product quality and other factors to choose the best synthesis path.

I don't know if 4-methyl-1H-imidazole-1-acetate (9CI) is in the market price range. This is a more professional chemical substance, and its price often varies for a variety of reasons.
First, the purity has a deep impact. For high purity, the preparation is difficult, the process is complicated, and the price must be high; for low purity, the preparation is easier, and the price may be slightly lower.
Second, the source of supply is also the key. If there are many suppliers and the competition is fierce, the price may stabilize or even drop slightly; if the supply is scarce, it will be monopolized, and the price may remain high.
Third, market demand also affects the price. If the demand for it increases sharply at a certain time, the supply exceeds the demand, and the price will rise; on the contrary, the demand is low, the supply exceeds the demand, and the price may decline.
Fourth, the preparation cost is also related to the price. The cost of raw materials, production equipment input, labor costs, etc. will all affect the final price. Raw materials are scarce and expensive, or the production process is cumbersome, resulting in high costs and high product prices.
For the exact price range, you can consult chemical product suppliers, chemical raw material trading platforms, or ask industry insiders in relevant professional forums, so that relatively accurate price information may be obtained.