1h Imidazole 1 2 7 Chlorobenzo B Thien 3 Yl Methoxy 2 2 4 Dichlorophenyl Ethyl
quinoline thiophene imidazole thiazole

1H-Imidazole, 1-(2-((7-chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-

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    655602

    Chemical Name 1H-Imidazole, 1-(2-((7-chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)-

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    Frequently Asked Questions

    As a leading 1H-Imidazole, 1-(2-((7-chlorobenzo(b)thien-3-yl)methoxy)-2-(2,4-dichlorophenyl)ethyl)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1H-Imidazole, 1- (2- ((7-chlorobenzo (b) thien-3-yl) methoxy) -2- (2,4-dichlorophenyl) ethyl) -
    1 - (2 - ((7 - chlorobenzo (b) thiophene - 3 - yl) methoxy) - 2 - (2,4 - dichlorophenyl) ethyl) - 1H - imidazole This compound is an important intermediate in organic synthesis. It is used in the field of medicinal chemistry and has extraordinary effects. It is often used to create new drugs, such as targeted therapeutic drugs for specific diseases.
    The cap can interact with specific targets in organisms due to its special chemical structure. In the process of drug development, chemists often use it as a basis to construct complex and biologically active molecular structures. In order to achieve the purpose of accurately acting on disease-related targets or regulating specific physiological processes in organisms.
    In the field of materials science, it may also have applications. Due to its structural properties, it may endow materials with unique electrical, optical or mechanical properties. For example, it may be used to prepare polymer materials with special functions, which may have potential uses in electronic devices, optical sensors, etc.
    Furthermore, in the study of organic synthesis reactions, as a key intermediate, it helps to explore novel synthesis methods and reaction paths. Chemists can use various chemical modifications to expand the variety and properties of organic compounds and promote the progress and development of organic synthesis chemistry.
    What are the physical properties of 1H-Imidazole, 1- (2- ((7-chlorobenzo (b) thien-3-yl) methoxy) -2- (2,4-dichlorophenyl) ethyl) -
    1 - (2 - ((7 - chlorobenzo (b) thiophene - 3 - yl) methoxy) - 2 - (2,4 - dichlorophenyl) ethyl) - 1H - imidazole The physical properties of this substance are as follows:
    Its properties may be crystalline solids. Due to the presence of many aromatic ring structures in the molecular structure, the intermolecular force is enhanced, and it tends to form a regular arrangement, so it is mostly crystalline.
    In terms of melting point, due to the fact that the molecule contains electron-absorbing groups such as chlorine atoms, the intermolecular force is enhanced, and the melting point is expected to be relatively high, or in the range of 150 ° C - 200 ° C. This temperature range is based on the melting point data of compounds with similar chlorine-containing aromatic ring structures.
    In terms of solubility, the substance is insoluble in water. Because its molecular body is composed of hydrophobic aromatic rings, and water molecules have polarity, the interaction between the two is weak according to the principle of similarity dissolution. However, its solubility may be better in organic solvents, such as dichloromethane, chloroform, N, N-dimethylformamide (DMF), etc. Halogenated hydrocarbon solvents such as dichloromethane and chloroform, whose molecular structures are similar to the partial structure of the substance, can interact with them through van der Waals forces; DMF, because of its strong polarity, can form hydrogen bonds and other interactions with polar groups in the molecules of the substance to facilitate dissolution. < Br >
    The density may be greater than that of water, because the molecule contains atoms with relatively large atomic mass such as chlorine atoms, resulting in an increase in molecular mass, and a higher mass at the same volume, so the density is higher.
    The physical properties of this substance are closely related to its unique chemical structure. Aromatic rings and structural units such as chlorine atoms jointly determine its melting point, solubility and density.
    What is the chemical synthesis method of 1H-Imidazole, 1- (2- ((7-chlorobenzo (b) thien-3-yl) methoxy) -2- (2,4-dichlorophenyl) ethyl) -
    The chemical synthesis of 1 - (2 - ((7 - chlorobenzo (b) thiophene - 3 - yl) methoxy) - 2 - (2,4 - dichlorophenyl) ethyl) - 1H - imidazole is a key exploration in the field of organic synthesis.
    To form this compound, 7 - chlorobenzo (b) thiophene - 3 - formaldehyde and 2,4 - dichloroacetophenone can be selected as the starting materials. 7-Chlorobenzo (b) thiophene-3-yl acetal was obtained by acetalylation of shilling 7-chlorobenzo (b) thiophene-3-yl acetal with appropriate alcohol under acid-catalyzed conditions.
    Then, 2,4-dichlorobenzophenone interacted with a base to form a carbon anion, which underwent nucleophilic addition reaction with 7-chlorobenzo (b) thiophene-3-yl acetal to form a key carbon-carbon bond to obtain an intermediate.
    Furthermore, the acetal structure of this intermediate is hydrolyzed to obtain an aldehyde group, and then the aldehyde group is converted into a hydroxyl group through a reduction reaction to obtain a key intermediate containing hydroxyl groups.
    Next, the hydroxyl-containing intermediate is condensed with imidazole under the action of a condensing agent such as carbodiimide reagents to obtain the target product 1- (2- ((7-chlorobenzo (b) thiophene-3-yl) methoxy) -2- (2,4-dichlorophenyl) ethyl) -1H-imidazole.
    During the reaction process, the precise control of the reaction conditions at each step is extremely important. Such as temperature, reaction time, and material ratio, all have a significant impact on the yield and purity of the reaction. During the acetalization reaction, the temperature should be controlled within a moderate range to ensure the smooth progress of the reaction and avoid the growth of side reactions. During the nucleophilic addition reaction, the strength and dosage of the base need to be precisely controlled to enable the moderate generation of carbon negative ions and prevent overreaction.
    In addition, the separation and purification steps after each step of the reaction should not be underestimated. Column chromatography, recrystallization and other methods can be used to remove impurities, improve the purity of the product, and meet the high quality requirements of synthesis.
    1H-Imidazole, 1- (2- ((7-chlorobenzo (b) thien-3-yl) methoxy) -2- (2,4-dichlorophenyl) ethyl) - what is the market price
    I don't know the price of 1H-imidazole, 1- (2- ((7-chlorobenzo (b) thiophene-3-yl) methoxy) -2- (2,4-dichlorophenyl) ethyl) in the market. However, in the era of "Tiangong Kaiwu", there is no such fine chemical synthesis, and the process has not yet reached this level, so it is difficult to have a market.
    In today's world, organic synthesis is flourishing, and such compounds may be used in medicine, chemical industry and other fields. The judgment of their market price is related to many ends. First, the price of raw materials, such as 7-chlorobenzo (b) thiophene-3-yl, 2,4-dichlorophenyl and other raw materials, if it is easy to obtain and abundant, the price may be inexpensive; if it is dilute and difficult to recover, the price will be high.
    Second, the synthesis is difficult and easy. If the synthesis method is complicated, it requires multiple steps of reaction, and the yield of each step is low, the energy consumption is large, and it takes a long time, and special reagents and equipment are required, the price will be high; if the method is simple, the yield is good, and the price may be reduced.
    Furthermore, market supply and demand are also important reasons. If there is a strong demand for this product in the fields of pharmaceutical research and development, but the supply is small, the price will rise; if the demand is low and the supply is large, the price will be lower.
    There are also quality points, and the price of high purity is higher than that of ordinary ones. Therefore, in order to know the exact price, it is necessary to carefully examine the raw materials, process, supply and demand, and quality to understand.
    What is the safety of 1H-Imidazole, 1- (2- ((7-chlorobenzo (b) thien-3-yl) methoxy) -2- (2,4-dichlorophenyl) ethyl) -
    1 - (2 - ((7 - chlorobenzo (b) thiophene - 3 - yl) methoxy) - 2 - (2,4 - dichlorophenyl) ethyl) - 1H - imidazole This product is related to its safety, which is described in detail today.
    However, the ancient and modern pharmacopoeia books have not found the exact safety record of this product. Due to its specific structure, it is composed of a variety of complex groups. Groups such as 7 - chlorobenzo (b) thiophene - 3 - yl, 2,4 - dichlorophenyl have certain chemical activity.
    From the perspective of past drug studies, compounds containing such complex halogenated aromatic hydrocarbon groups may have latent risks. For example, some drugs containing chlorobenzene ring structure can cause liver and kidney function damage after long-term use. When metabolized in vivo, or producing electrophilic active intermediates, they covalently bind to biological macromolecules and disrupt normal physiological and biochemical processes.
    Also consider its imidazole structure. Although imidazole compounds are common in many drugs and can participate in a variety of physiological activity regulation, in this specific structure, they interact with surrounding groups or cause unpredictable effects. or affect the absorption, distribution, metabolism and excretion of drugs in the body, thereby affecting their safety.
    In addition, the newly synthesized complex compounds lack a large number of preclinical toxicological studies and clinical trial verification, and it is difficult to determine the impact of their long-term use on various human systems, such as cardiovascular, nervous, immune and other systems. Or acute toxicity, such as triggering immediate reactions such as allergies and shock; or chronic toxicity, accumulated over a long time, impairing important organ functions.
    In summary, the safety of 1- (2- ((7-chlorobenzo (b) thiophene-3-yl) methoxy) -2- (2,4-dichlorophenyl) ethyl) -1H-imidazole is difficult to draw a conclusion due to the complex structure and lack of research. It is still necessary to conduct rigorous scientific research to clarify it.