1H-benzimidazole-7-carboxylic acid, 2-(4-pyridinyl)-

1H-benzimidazole-7-carboxylic acid, 2- (4-pyridyl) is mostly used in the field of medicinal chemistry in today's world. In pharmaceutical research, it is often a key intermediate. The structure of Geinbenzimidazole and pyridine endows it with unique chemical activities and pharmacological properties.
According to the research of past physicians, many compounds containing this structure have been carefully developed and are now emerging in the treatment of diseases. First, in the development of anti-tumor drugs, this compound may inhibit the proliferation of tumor cells through a specific mechanism, and then it is expected to become a new anti-cancer weapon. Second, in the creation of anti-inflammatory drugs, it may regulate inflammation-related signaling pathways in the body, reduce inflammatory responses, and bring good news to patients with inflammatory diseases.
Furthermore, due to the uniqueness of its structure, it has also begun to emerge in the field of materials science. It may be used to prepare functional materials, such as materials with special optical and electrical properties, in electronic devices, optical devices, etc., or have other uses, but it is still in the exploratory stage, and more research is needed to understand its potential. In short, the uses of 1H-benzimidazole-7-carboxylic acid and 2- (4-pyridyl) in the fields of medicine and materials are yet to be further explored to benefit everyone.

1H-benzimidazole-7-carboxylic acid, 2- (4-pyridyl), its physical properties are as follows:
This compound is often crystalline, and the crystalline form is either fine needle-like or prismatic, and it has a certain luster. Its color is usually almost white, but it may be slightly yellowish due to differences in purity.
When it comes to melting point, it is about a certain temperature range. This temperature is the key node for its conversion from solid to liquid. Accurate determination of melting point is extremely important for identification and purity determination.
In terms of solubility, it varies in common organic solvents. In polar organic solvents, such as ethanol and dimethyl sulfoxide, it has a certain solubility and can be moderately dissolved to form a uniform solution; while in non-polar organic solvents, such as n-hexane and toluene, the solubility is poor, insoluble and often dispersed.
Density is also one of its important physical properties, and its specific value can be obtained by measurement. This value reflects the mass of its unit volume, which is of great significance for material calculation and process design.
In addition, the stability of the compound also belongs to the category of physical properties. Under normal temperature, pressure and dry environment, the properties are relatively stable and can be stored for a long time without significant deterioration. However, if it is placed in a high temperature, high humidity or strong light environment, or chemical changes occur, its structure and properties will change.

To prepare 1H-benzimidazole-7-carboxylic acid, 2- (4-pyridyl), the method is as follows:
Take the pyridine derivative first, and use appropriate reagents and conditions to react with the precursor containing the benzimidazole structure. A suitable catalyst can be selected to promote the condensation reaction between the two at a suitable temperature and reaction time. In this process, it is necessary to pay attention to the pH of the reaction environment, and a buffer can be used to adjust it to a suitable pH value to facilitate the reaction to proceed in the desired direction.
After the reaction is completed, the product or mixed with impurities needs to be separated and purified. Column chromatography can be used to select the appropriate stationary phase and mobile phase to separate the product from the impurities. Recrystallization can also be used to select the appropriate solvent according to the solubility of the product and the impurities in different solvents to crystallize the product and remove the impurities.
Or another way can be tried, using benzimidazole-7-carboxylic acid as the starting material, through a specific substitution reaction, the introduction of 2- (4-pyridyl). Among them, the pyridyl substitution reagent with suitable activity needs to be selected, and attention should be paid to the control of reaction conditions, such as temperature, reaction time and proportion of reactants, which all have an important impact on the reaction effect. After the reaction, the separation and purification steps described above are also used to obtain a pure 1H-benzimidazole-7-carboxylic acid, 2- (4-pyridyl) product.
In short, the synthesis method depends on the actual situation, such as the availability of raw materials, equipment conditions and requirements for product purity, etc., select the optimal route and fine operation to obtain satisfactory results.

What you are inquiring about is the price range of 1H-benzimidazole-7-carboxylic acid, 2- (4-pyridyl) in the market. However, the price of this product is difficult to determine, and it is subject to many factors.
First, it is difficult to produce. If the synthesis method is complicated, and rare reagents or harsh reaction conditions are required, the cost will be high, and the price will follow. If the preparation is relatively simple, the raw materials are common and inexpensive, the price will be relatively easy.
Second, the market supply and demand situation. If there is a large demand for this product and the supply is limited, the price will rise; on the contrary, if the market demand is small and there is more production, the price will decline.
Third, the quality is different. High purity, less impurities, the price must be higher than ordinary.
Fourth, the place of production and the way of trade. Production costs vary in different regions, and trade factors such as transportation and tariffs also affect their prices.
Because the specific market situation is not detailed, it is difficult to determine the price range. If you want to know the details, you can go to the chemical raw material trading market, chemical e-commerce platform, or ask relevant manufacturers and distributors, they can give you closer price information.

1H-benzimidazole-7-carboxylic acid, 2- (4-pyridyl), there are many manufacturers of this product. Due to the prosperity of the chemical industry, many manufacturers are involved in the manufacture of such compounds.
In the land of the East, there are many fine chemical enterprises with exquisite skills, with rigorous processes and exquisite equipment, they are invested in the production of this product. They pay attention to quality, and strive to produce products of the highest standard in the selection of raw materials, control of reaction conditions, purification and refining.
There are also professional chemical companies in Western countries. With their deep scientific research foundation and advanced technical means, they occupy a place in the production of 1H-benzimidazole-7-carboxylic acid and 2- (4-pyridyl). Their R & D strength is strong, and they continue to explore ways to optimize production to improve product performance and purity.
In addition, some emerging chemical companies have also emerged. Driven by innovation, they introduce novel processes and concepts to inject new vitality into the production of this compound. Or work hand in hand with universities and scientific research institutions to borrow their wisdom to improve production skills and expand application fields.
In summary, the manufacturers of 1H-benzimidazole-7-carboxylic acid and 2- (4-pyridyl) are all over the world, each with its own strengths, and jointly promote the development of this field.