1h Benzimidazole 6 Carboxylic Acid 4 Hydroxy 2 Methyl 1 Phenylmethyl
quinoline thiophene imidazole thiazole

1H-Benzimidazole-6-carboxylic acid, 4-hydroxy-2-methyl-1-(phenylmethyl)-

    Specifications

    HS Code

    469043

    Chemical Formula C16H14N2O3
    Molecular Weight 282.3 g/mol
    Appearance Solid (predicted)
    Boiling Point 577.4 °C at 760 mmHg (predicted)
    Melting Point 224 - 226 °C
    Logp 2.61 (predicted)
    Solubility Soluble in DMSO, DMF (predicted)
    Pka 9.52 (predicted)
    Density 1.316 g/cm³ (predicted)
    Flash Point 303.0 °C (predicted)

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    General Information
    Where to Buy 1H-Benzimidazole-6-carboxylic acid, 4-hydroxy-2-methyl-1-(phenylmethyl)- in China?
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    Frequently Asked Questions

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    What are the chemical properties of 1H-benzimidazole-6-carboxylic acid, 4-hydroxy-2-methyl-1 - (phenylmethyl) -
    This is a description of a chemical substance, which contains 1 hydrogen ion, phenyl group, carboxyl group, 6 carboxyl groups, 4 amino groups, 2 methyl groups, and 1 (phenyl gold group). Its chemical properties are to be known.
    This chemical substance has hydrogen ions, so it is acidic and can neutralize with bases. In case of hydroxide ions, hydrogen ions combine with it to form water. Its many carboxyl groups also enhance acidity, and carboxyl groups can ionize hydrogen ions. And carboxyl groups can participate in esterification reactions, and alcohol can remove a molecule of water under acid catalysis to form ester compounds.
    Furthermore, amino groups are basic and can react with acids, accept protons, and combine with hydrogen ions to form ammonium ions. The amino group can also participate in the amidation reaction, condensation with the carboxyl group to form an amide bond.
    The methyl group, a hydrocarbon group, has a certain hydrophobicity, which will affect the solubility of the substance, making it less soluble in water and more soluble or enhanced in organic solvents. The phenyl group is an aromatic hydrocarbon group, which imparts a certain stability and conjugation effect to the substance, affecting its electron cloud distribution and reactivity.
    This chemical substance contains a variety of functional groups and is rich in chemical properties. It can participate in a variety of chemical reactions. It may have important uses in organic synthesis, medicinal chemistry and other fields. It can use its functional group properties to design and synthesize compounds with specific structures and functions.
    What are the main uses of 1H-benzimidazole-6-carboxylic acid, 4-hydroxy-2-methyl-1 - (phenylmethyl) -
    1H-borax-6-carboxylic acid, 4-amino-2-methyl-1 - (boronyl methyl) has a wide range of main uses. In the field of medicine, it can participate in the construction of drug molecules due to its unique chemical structure. For example, in the development of some new antibacterial drugs, its properties can be used to enhance the targeting and affinity of drugs to specific bacteria and improve the antibacterial effect. In the field of materials science, it is often used to prepare functional materials. For example, when synthesizing polymer materials with special optical and electrical properties, it acts as a key monomer to give the material unique properties, such as making the material have better electrical conductivity or fluorescence properties, and is used in optoelectronic devices. In the field of chemical synthesis, it is an important intermediate. During the synthesis of many complex organic compounds, it can be converted into various target products through a series of reactions, such as some fine chemicals containing boron, which are widely used in coatings, catalysts and other industries. In the agricultural field, appropriate addition of preparations containing this ingredient can adjust soil pH, supplement boron, nitrogen and other elements, promote crop growth, and improve crop disease resistance and yield.
    What is the synthesis method of 1H-benzimidazole-6-carboxylic acid, 4-hydroxy-2-methyl-1 - (phenylmethyl) -
    To prepare 1- (benzylethyl) -6-carboxyl-4-amino-2-methylphenol, the synthesis method is as follows:
    First, take a suitable raw material, use benzyl bromide and an active reagent containing ethyl group, in a suitable solvent, under the catalysis of a base, carry out nucleophilic substitution reaction. For bases, such as potassium carbonate, acetonitrile can be selected as a solvent. This step aims to introduce benzyl and ethyl to form a benzylethyl structure.
    Next, carboxylation of the resulting product is carried out. Methods such as carbon dioxide and metal reagents can be used. The metal magnesium is first reacted with halogenated hydrocarbons to make Grignard reagent, and then carbon dioxide is introduced, and then the carboxyl group can be introduced at a specific position after acidification treatment.
    Then, for the introduction of amino groups, the method of nitro reduction can be used. First, the benzene ring is nitrified at a specific position with an appropriate nitrifying reagent, such as a mixed acid of nitric acid and sulfuric acid, to obtain a nitro-containing product. Then the nitro group is reduced to an amino group with a reduction system such as iron powder and hydrochloric acid.
    As for the introduction of methyl groups, the compound containing methyl groups can be used in the selection of raw materials in the early stage, or at a suitable stage, a methylating reagent, such as iodomethane, can be used in the presence of a base
    After each step of the reaction, the product needs to be purified by suitable separation and purification methods, such as column chromatography, recrystallization, etc., to improve the purity of the product and ensure that the reaction proceeds in the desired direction. Finally, the synthesis of 1- (benzylethyl) -6-carboxyl-4-amino-2-methylphenol is achieved.
    1H - benzimidazole - 6 - carboxylic acid, 4 - hydroxy - 2 - methyl - 1 - (phenylmethyl) - what is the price range in the market
    What is the price range of 1H 🥰, anthracyridine, 6-carboxyl, 4-amino, 2-methyl, and 1 - (benzylmethyl) in the market today? This question is quite difficult, and various factors need to be considered in detail.
    The price on the market often depends on the purity of the material, the state of supply and demand, and the difficulty of preparation. If the purity of the product is extremely high, it is almost flawless, and it must be worth a high price; on the contrary, if there are a little more impurities, the price will tend to be lower. On the supply and demand side, if there are many seekers and few suppliers, the price will rise; if the supply exceeds the demand, the price will fall. If the preparation is complex, it requires delicate methods and rare materials, and the price is not cheap; if the preparation is easy, the price is affordable or close to the people.
    However, anthracene-pyridine compounds are often used in scientific research, medicine and other fields because of their special structure. Among them, the modification of 6-carboxyl, 4-amino, 2-methyl, 1 - (benzylmethyl) increases their characteristics and uses. If used in cutting-edge scientific research, the purity requirements are strict, and the price may reach hundreds of gold per gram, or even thousands of gold. If used in general industrial use, the purity requirements are slightly lower, and the price may be tens of gold per gram.
    But the market situation is irregular, and the price can change at any time. Merchant competition and the rise and fall of raw materials can all make prices fluctuate. To know the exact price range, you can get an accurate figure by consulting a professional chemical material supplier or checking the data of recent market transactions.
    1H-benzimidazole-6-carboxylic acid, 4-hydroxy-2-methyl-1 - (phenylmethyl) - what are the relevant derivatives
    In the ancient texts of Dan, if the related derivatives of "1H 🥰 -Ligazine-6-carboxylic acid, 4-amino-2-methyl-1 - (Ligzyl methyl) " are mentioned, the common ones are ligustrazine and its many derivatives.
    Ligustrazine is an alkaloid monomer extracted from the traditional Chinese medicine Ligustrazine. Because its structure contains the above groups, it has many pharmacological activities. Ligustrazine can dilate blood vessels, increase coronary flow, improve myocardial oxygen supply, and is very critical in the treatment of cardiovascular diseases. And it can reduce platelet surface activity, inhibit platelet aggregation, and reduce the chance of thrombosis.
    Derivatives derived from "1H 🥰 -Ligustrazine-6-carboxylic acid, 4-amino-2-methyl-1 - (Ligustrazyl methyl) ", some of which have been structurally modified to improve fat solubility, more easily penetrate the blood-brain barrier, and have made a name for themselves in the treatment of brain diseases. For example, they can improve cerebral ischemia-reperfusion injury and protect nerve cells. Some enhance stability, have longer-lasting efficacy, and have obvious advantages in long-term treatment of chronic diseases. In addition, some derivatives also exhibit anti-inflammatory and antioxidant properties, which are also important in the fields of immune regulation and anti-oxidative stress damage.