1h Benzimidazole 5 Methoxy 2 4 Methoxy 3 5 Dimethyl 2 Pyridinyl Methyl Sulfinyl Magnesium Salt 1 1
Quinoline Thiophene Imidazole Thiazole
1H-benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, magnesium salt (1:1)
Chemical Name 1H-benzimidazole, 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-, magnesium salt (1:1)
Common Name esomeprazole magnesium
Molecular Formula C34H36MgN6O6S2
Molecular Weight 670.94 g/mol
Appearance White to off - white powder
Solubility Sparingly soluble in water
Pka pKa1 = 3.8, pKa2 = 9.1
Melting Point 248 - 251 °C
Pharmaceutical Class Proton - pump inhibitor
Mechanism Of Action Inhibits the H+/K+ - ATPase enzyme in gastric parietal cells
Clinical Uses Treatment of gastroesophageal reflux disease (GERD), peptic ulcer disease
FAQ

What is the chemical structure of 1H-benzimidazole, 5-methoxy-2- [[ (4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfinyl] -, magnesium salt (1:1)

This is related to the chemical structure of pantoprazole magnesium. Its chemical name is 1H-benzimidazole, 5-methoxy-2 - [ (4-methoxy-3,5-dimethyl-2-pyridyl) methyl] sulfinyl] -, magnesium salt (1:1).

Looking at its structure, 1H-benzimidazole is the base, which is a kind of nitrogen-containing heterocyclic parent nucleus. It has aromatic properties and unique electron cloud distribution, which is crucial in the expression of many drug activities. The 5-methoxy group is a methoxy group added to the 5 position of the benzimidazole ring. This methoxy group can use its electronic effect to affect the charge distribution and polarity of the molecule as a whole, and has an important impact on the binding of drugs to receptors.

And the 2 - [ (4-methoxy-3,5-dimethyl-2-pyridyl) methyl] sulfinyl] part, the pyridine ring is also a nitrogen-containing heterocycle, and the substitution of 4-methoxy and 3,5-dimethyl further changes the electron cloud density and steric resistance of the pyridine ring. The sulfinyl group is attached between the pyridyl methyl group and the benzimidazole ring, and this structural fragment is also critical for the regulation of drug activity, or involves the interaction with specific targets.

Magnesium salt (1:1) shows that this compound binds to magnesium ions in a 1:1 ratio to form a salt structure. The coordination of magnesium ions can change the physical and chemical properties of the compound, such as solubility and stability, which is of great significance in pharmaceutical preparations and metabolic processes in vivo. This structural feature endows pantoprazole magnesium with unique pharmacological activity and is often used as a proton pump inhibitor in the treatment of gastric acid-related diseases.

What are the main uses of 1H-benzimidazole, 5-methoxy-2- [[ (4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfinyl] -, magnesium salt (1:1)

1H-benzimidazole, 5-methoxy-2-[ (4-methoxy-3,5-dimethyl-2-pyridyl) methyl] sulfinyl], magnesium salt (1:1), this is the chemical name of the drug Pantoprazole Magnesium. Its main uses are extraordinary, and it is used in the medical system to treat various diseases of the digestive system.

View stomach acid-related diseases, such as gastric ulcers, the inner lining of the stomach is eroded by gastric acid, causing sores. Magnesium pantoprazole can greatly exert its ability, inhibit the secretion of gastric acid, create a suitable environment, help the sore heal, relieve the pain of epigastric pain and noisy pantothenic acid in patients.

Duodenal ulcer is also a common disease, and magnesium pantoprazole is also a symptomatic medicine. The duodenum is damaged due to stomach acid, and the lining is damaged. This medicine can inhibit the acid protective membrane, promote its recovery, and make the patient's diet and daily life gradually return to normal.

Reflux esophagitis is also in its treatment scope. The esophagus is burned due to acid reflux, causing inflammation. Pantoprazole magnesium inhibits acid, reduces the irritation of reflux stomach acid to the esophagus, relieves heartburn, chest pain and other diseases, subsides esophageal inflammation, and restores its normal physiological function.

Because of digestive system diseases, it has plagued people's health for a long time. Pantoprazole magnesium has become a sharp tool in the hands of doctors to treat such diseases, relieving pain for patients and enabling them to enjoy good health.

What is the pharmacological effect of 1H-benzimidazole, 5-methoxy-2- [[ (4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfinyl] -, magnesium salt (1:1)

1H - benzimidazole, 5 - methoxy - 2 - [ (4 - methoxy - 3,5 - dimethyl - 2 - pyridyl) methyl] sulfinyl -, magnesium salt (1:1), this drug is called pantoprazole magnesium, its pharmacological effects are as follows:

Pantoprazole magnesium is a proton pump inhibitor, which is crucial for the treatment of epigastric diseases. The cells of the stomach wall of the human body secrete gastric acid, and this process requires the help of a proton pump. Pantoprazole magnesium can precisely act on the proton pump.

After it enters the human body with a specific chemical structure, it runs with qi and blood to the gastric parietal cells. At the proton pump on which the gastric parietal cells secrete gastric acid, pantoprazole magnesium is closely bound to it. In this way, it is like setting a barrier in the main channel of gastric acid secretion, which effectively inhibits the activity of the proton pump.

After the activity of the proton pump is suppressed, the ability of the gastric parietal cells to secrete gastric acid is greatly reduced, resulting in a significant reduction in gastric acid secretion. This pharmacological effect is extremely beneficial for the treatment of many epigastric diseases. For example, epigastric pain, pantothenic acid, heartburn and other symptoms caused by excessive gastric acid, pantoprazole magnesium can reduce such discomfort by inhibiting gastric acid secretion.

And because it can effectively control gastric acid secretion, it also creates a good environment for the healing of gastric and duodenal ulcers, and helps the damaged gastrointestinal mucosa to repair, thereby promoting the recovery of the disease and protecting the health of human epigastric.

What are the side effects of 1H-benzimidazole, 5-methoxy-2- [[ (4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfinyl] -, magnesium salt (1:1)

5-Methoxy-2-[ (4-methoxy-3,5-dimethyl-2-pyridyl) methyl] sulfinyl-1H-benzimidazole magnesium salt (1:1), although this medicine has therapeutic effect, it also has various side effects.

It may cause gastrointestinal discomfort, such as nausea, vomiting, abdominal pain, diarrhea, etc. People with weak spleen and stomach are more susceptible to disturbance when taking it. The transportation and transformation are abnormal, the qi does not rise, and the turbid air does not fall, and the symptoms of vomiting and diarrhea and abdominal pain are seen.

may also affect the liver, damaging the liver's function of dredging. The liver is responsible for dredging, which is related to the smooth regulation of qi and blood. If the dredging is negligent, the qi and blood will not run smoothly, or the ribs will be swollen and painful, jaundice and other diseases. Long-term use, especially pay attention to the health of the liver, and regularly check the liver function.

The nervous system is also implicated, which can cause headache, dizziness, drowsiness, fatigue, etc. The primordial spirit of a person resides in the brain, and the brain is the marrow sea. The side effects of this medicine disturb the marrow sea, and the clear yang will not rise, so headache and dizziness; if the spirit is suppressed, it will be drowsiness and

And may cause allergic symptoms, skin rash, itching, and even exfoliative dermatitis, which is life-threatening. The skin surface is used by Weiqi, which is not solid, and the poison and evil of the medicine are invaded, so allergies.

When taking medicine, the doctor should carefully review the patient's body shape, weigh the advantages and disadvantages, and use it cautiously. Patients should also follow the doctor's instructions, pay close attention to their own changes, and seek medical treatment at an abnormal speed. Do not ignore it.

What is the market outlook for 1H-benzimidazole, 5-methoxy-2- [[ (4-methoxy-3, 5-dimethyl-2-pyridinyl) methyl] sulfinyl] -, magnesium salt (1:1)

1H-benzimidazole, 5-methoxy-2 - [ [( 4-methoxy-3,5-dimethyl-2-pyridyl) methyl] sulfinyl] -, magnesium salt (1:1), that is, pantoprazole magnesium, is quite promising in the pharmaceutical market.

The number of patients with gastrointestinal diseases is large and growing. Gastric acid-related diseases, such as gastric ulcers, duodenal ulcers, and reflux esophagitis, plague countless people. As a proton pump inhibitor, magnesium pantoprazole has a significant effect on inhibiting gastric acid secretion and can effectively relieve the above diseases, so the market demand is quite large.

In terms of industry competition, although there are many competing products of proton pump inhibitors, magnesium pantoprazole occupies a place in the market due to its unique advantages, such as accurate efficacy, high safety, and good tolerance. Many pharmaceutical companies also attach great importance to it and continue to invest in research and development resources, hoping to improve product quality and competitiveness.

From the perspective of development trends, with the improvement of public health awareness, the demand for efficient and safe gastrointestinal treatment drugs is becoming increasingly strong. With its own characteristics, magnesium pantoprazole is expected to further expand its market share. In addition to the progress of scientific research, more dosage forms may be developed to meet the needs of different patients, and the market prospect is promising. It will continue to play an important role in the treatment of gastrointestinal diseases and contribute more to the health and well-being of the people.