1h Benzimidazole 5 Carboxylic Acid Methyl Ester
quinoline thiophene imidazole thiazole

1H-Benzimidazole-5-carboxylic acid methyl ester

    Specifications

    HS Code

    509486

    Chemical Formula C9H9N2O2
    Molar Mass 177.18 g/mol
    Appearance Solid (Typical appearance, actual may vary)
    Melting Point Data may vary depending on purity
    Boiling Point Data may vary depending on purity
    Solubility In Water Low solubility (Generally expected for this type of compound)
    Solubility In Organic Solvents Soluble in some organic solvents like ethanol, dichloromethane (Typical behavior)
    Density Data may vary depending on form
    Pka Related to the acidic nature of carboxylic acid group (Value depends on environment)
    Uv Vis Absorption Absorbs in specific UV regions due to aromatic structure (Absorption peaks vary)

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    General Information
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    Frequently Asked Questions

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    What are the physical properties of methyl 1H-benzimidazole-5-carboxylate?
    The physical properties of borax ethyl acetate can be investigated. Borax is mostly colorless and translucent crystals or white powders. Its taste is salty, cold in nature, and can slowly weathering in air. The crystal water of borax will gradually lose when heated, and melt into a glassy thing at a higher temperature. Its solubility in water increases significantly with increasing temperature, and the aqueous solution is weakly alkaline.
    And ethyl acetate is a colorless and transparent liquid with an aromatic taste and good volatility. Its boiling point is about 77 ° C, its density is less than that of water, and it can form a binary azeotrope with water. Ethyl acetate is slightly soluble in water, but can be miscible with various organic solvents such as alcohols, ethers, and chloroform. The physical properties of the two are different. Borax is mostly solid at room temperature, with certain solubility and special chemical properties; ethyl acetate is liquid, with its own characteristics of volatility and solubility. Borax is used in many fields such as industry, medicine, etc., such as in glass manufacturing, heat removal and detoxification for external use in medicine; ethyl acetate is often used as an organic solvent and is widely used in coatings, inks, fragrances and other industries. Due to their unique physical properties, they play important functions in different fields.
    What are the chemical properties of methyl 1H-benzimidazole-5-carboxylate
    Methyl hydroxyacetate is an organic compound. Its chemical properties are unique and valuable for investigation.
    As far as its reaction with alkali is concerned, the ester groups in methyl hydroxyacetate can be hydrolyzed in alkali solution. For example, if it is placed in a sodium hydroxide solution, it will hydrolyze to form sodium hydroxyacetate and methanol. The principle of this reaction is that the hydroxide ion launches a nucleophilic attack on the carbon atom of the ester carbonyl group, which then breaks the ester bond.
    Methyl hydroxyacetate can also be hydrolyzed in an acidic environment, but this hydrolysis process is a reversible reaction. With sulfuric acid as a catalyst, it will gradually hydrolyze into hydroxyacetate and methanol under heating conditions. As the reaction progresses, if the generated methanol is removed in time, according to Le Chatelier's principle, the equilibrium will shift towards the formation of hydroxyacetic acid, which will promote the reaction to be more complete. Methyl hydroxyacetate can also participate in the esterification reaction. When it meets with other carboxylic acids, new ester compounds can be formed under the catalysis of acids. For example, when reacted with acetic acid, a new mixed ester will be formed. This process involves the dehydration and condensation between the alcohol and the carboxylic acid.
    Because there are both hydroxyl and ester groups in the molecule, methyl hydroxyacetate can also undergo some special reactions. Hydroxyl groups can be oxidized, for example, by using a suitable oxidizing agent, they can be oxidized to aldehyde groups or even carboxyl groups, thereby deriving more compounds with different properties. At the same time, ester groups can also participate in some related reactions such as transesterification. By reacting with different alcohols under specific conditions, ester groups can be transformed to form a series of ester products with different structures and properties. Such diverse reaction characteristics make methyl hydroxyacetate widely used in the field of organic synthesis and can be used as a key intermediate in the synthesis of many fine chemicals and drugs.
    What is the main use of methyl 1H-benzimidazole-5-carboxylate?
    Borax sodium acetate has a wide range of uses. In the field of medicine, it is often used as a disinfectant and preservative. Because of its antibacterial ability, it can kill many bacteria and protect the human body from disease, and it is common in wound disinfection and ophthalmic medicine.
    In industry, it is of great significance in glass manufacturing. It can increase the transparency, strength and heat resistance of glass, making glass products more beautiful and durable, such as high-grade optical glass and heat-resistant glassware. In the enamel industry, it can also improve the performance of enamel products, making their surface smooth and bright in color, not easy to peel off.
    In the field of food, it was occasionally used by illegal people in the past to increase food toughness, brittleness and preservative, but now its toxicity is known, which is strictly prohibited.
    In scientific research experiments, sodium borax acetate is often used as a buffer to stabilize the pH of the solution, ensure the stability of the experimental conditions, and make the experimental results accurate and reliable.
    In short, sodium borax acetate has a variety of uses, and it needs to be used in accordance with regulations. It must not be used in food to prevent harm to human health. It should also be used reasonably and scientifically in other fields in order to achieve its full effect.
    What are the synthesis methods of 1H-benzimidazole-5-carboxylic acid methyl ester
    There are several ways to make ethyl caseate. First, it can be esterified by butyric acid and ethanol under the condition of acid catalyst. Among them, the acid is often sulfuric acid and the like, which can promote the speed of the reaction, so that the phase of butyric acid and ethanol is combined to form ethyl caseate and water. The reaction formula is roughly as follows: butyric acid + ethanol-ethyl caseate + water. During the reaction, it is necessary to control the temperature. Generally, under moderate temperature, the reaction can be better, and the reflux device is used to make the reactants fully function. After separation and purification, pure ethyl caseate can be obtained.
    Second, the method of acyl chloride can be borrowed. First, the butyric acid is made into tyroyl chloride, which is often interacted with by reagents such as thionyl chloride. The butyric acid is changed into tyroyl chloride, and sulfur dioxide and hydrogen chloride gas are generated at the same time. Then, the tyroyl chloride meets ethanol, and the two react quickly to form ethyl caseate and hydrogen chloride. This way, the rate is often faster than the esterification reaction, but the reagents used are more corrosive and need to be carefully protected during operation.
    Third, the method of transesterification can also be carried out. The transesterification reaction is carried out with the help of a certain ester and ethanol, with the help of a specific catalyst. For example, ethyl acetate and ethanol are interacted with bases or specific metal salt catalysts, and groups are exchanged between molecules to obtain ethyl caseate. The conditions in this way may be milder, but the appropriate ratio of catalyst and reactant should be selected to obtain a higher yield.
    All these methods have their own advantages and disadvantages. In practice, according to the availability of raw materials, cost considerations, and product purity, the best conditions for making ethyl caseate can be achieved.
    What are the precautions for the storage and transportation of 1H-benzimidazole-5-methyl carboxylate?
    Stable storage of ethylene malonate is an important substance in organic chemistry. When storing and transporting, pay attention to many matters.
    First, pay attention to the storage environment. Ethylene malonate should be stored in a cool, dry and well-ventilated place. This is because the substance is easily decomposed by heat, and the high temperature environment may cause it to deteriorate. Therefore, the warehouse temperature should be controlled within an appropriate range and should not be too high. If the temperature is too high, ethylene malonate may chemically react and damage its quality. And humid environment or cause it to hydrolyze, which affects the use efficiency.
    Second, the transportation process must ensure safety. Ethylene malonate may have certain toxicity and irritation, and must be strictly followed when transporting relevant regulations and properly packaged. Packaging materials should be able to prevent leakage and collision, so as to ensure the integrity of the material during transportation. Transport personnel should also be familiar with its characteristics, and can properly deal with emergencies.
    Third, avoid contact with incompatible substances. Ethylene malonate encounters with certain oxidants, acids, etc., or causes violent chemical reactions, even causing dangers such as combustion and explosion. During storage and transportation, it is necessary to isolate such substances, place them separately and transport them.
    Fourth, make labels and records. Storage and transportation containers should be clearly marked with the name, characteristics, danger warnings and other information of ethylene malonate. And detailed records of its entry and exit time, quantity, source, whereabouts, etc. for traceability and management.
    In short, the storage and transportation of ethylene malonate requires comprehensive consideration of various factors and careful operation to ensure personnel safety and material quality, and to avoid dangerous accidents.