1h Benzimidazole 2 Chloromethyl 1 Methyl
quinoline thiophene imidazole thiazole

1H-benzimidazole, 2-(chloromethyl)-1-methyl-

    Specifications

    HS Code

    375277

    Chemical Formula C9H10ClN3
    Molecular Weight 195.65 g/mol
    Solubility In Water Low solubility (organic compound with polar and non - polar parts)
    Solubility In Organic Solvents Soluble in common organic solvents like dichloromethane, chloroform
    Hazard Class May be harmful if swallowed, inhaled or in contact with skin (general for halogen - containing organic compounds)

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    General Information
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    Frequently Asked Questions

    As a leading 1H-benzimidazole, 2-(chloromethyl)-1-methyl- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What is the main use of 1H - benzimidazole, 2 - (chloromethyl) -1 - methyl -
    2 + - (chloromethyl) -1 -methyl-1H -benzimidazole is a widely used substance. In the field of medicine, it can be used as a key intermediate in drug synthesis. Due to its unique chemical structure, it can participate in the construction of many drug molecules, or have antibacterial, antiviral and other effects, contributing to the creation of medicine.
    In the field of materials science, it also plays an important role. It can be used to prepare special polymer materials, improve the properties of materials such as thermal stability and mechanical properties, and make the materials have better application prospects in high-end fields such as aerospace and electronics.
    In organic synthesis chemistry, it is often used as a catalyst or ligand for organic reactions. With the lone pair of electrons of nitrogen atoms in its structure, it can complex with metal ions, catalyze a variety of organic reactions, improve reaction efficiency and selectivity, and greatly assist the synthesis of complex organic compounds.
    Furthermore, in the agricultural field, it may be used as a synthetic raw material for pesticide active ingredients, providing the possibility for the development of new high-efficiency and low-toxicity pesticides, assisting in the control of crop diseases and insect pests, and ensuring agricultural production. In short, 2 - (chloromethyl) -1 - methyl - 1H - benzimidazole has important application value in many fields, and is of great significance to promote the development of various industries.
    What are the physical properties of 1H - benzimidazole, 2 - (chloromethyl) -1 - methyl -
    2 - (chloromethyl) -1 - methyl - 1H - benzimidazole, this physical property is involved in the chemical industry. It has many physical properties, and listen to me in detail.
    Looking at its appearance, under room temperature and pressure, or white to light yellow crystalline powder, fine and uniform, just like frost and snow. This form is easy to store and transport, and it is also easy to handle in many chemical processes.
    As for the melting point, it is about a certain value range, and this value is extremely critical for controlling its thermal change. When heated to this temperature, the substance slowly melts from a solid state to a liquid state, like melting ice and snow. The accurate determination of the melting point can help to judge its purity. The higher the purity, the closer the melting point is to the theoretical value, and the error is very small.
    In terms of solubility, it has a certain performance in organic solvents. For example, in common organic solvents such as ethanol and acetone, it can show different degrees of solubility. In ethanol, it may be partially dissolved to form a clear or slightly turbid solution, just like a light rain into a stream. This property can be used in chemical synthesis and separation and purification processes. With the help of different solvents to achieve the difference in solubility, substance separation and purification can be achieved.
    In addition, its density is also an important physical property. Under specific conditions, it has a relatively fixed density value, which is related to its volume and mass in various systems. In a liquid mixing system, the density difference determines its stratification or homogeneous dispersion state. If it is mixed with other liquids with different densities, or the stratification phenomenon occurs due to the density difference, such as oil and water, which can provide a theoretical basis for chemical separation operations.
    Furthermore, its stability cannot be ignored. Under normal environmental conditions, it is relatively stable. In case of extreme conditions such as high temperature, strong acid and alkali, the structure may change, triggering a chemical reaction. In case of strong acid, the nitrogen atom on the benzimidazole ring may protonate with the acid, changing the molecular structure and properties. Therefore, caution must be used when storing and using to avoid such extreme conditions.
    What is the chemical synthesis method of 1H - benzimidazole, 2- (chloromethyl) -1 - methyl -
    To prepare 2 - (chloromethyl) - 1 - methyl - 1H - benzimidazole, the method is as follows:
    First take an appropriate amount of 1 - methyl benzimidazole, which is the starting material for the reaction. Place it in a suitable reaction vessel, which needs to be clean and dry to avoid impurities.
    Then, slowly add a specific amount of chloromethylating reagent, such as chloromethyl ether, to it. Time should be added slowly to prevent excessive reaction. In this process, precise temperature control is required, usually maintained in a moderate range, such as low temperature to room temperature, depending on the specific situation. Because the temperature is too high, or the side reaction is raw, the product is impure; if the temperature is too low, the reaction is slow and takes a long time.
    Add it up and stir the mixture to make the reactants fully contact and promote the smooth progress of the reaction. The stirring time also needs to be moderate. If it is too long, it may increase energy consumption and damage equipment. If it is too short, the reaction will not be complete.
    During the reaction period, thin-layer chromatography can be used to observe the reaction process from time to time. When the raw material point fades away, the product point is obvious and does not change again, indicating that the reaction is near the end. After the
    reaction is completed, the resulting mixture is treated in a suitable manner, such as extraction, distillation, recrystallization, etc., to remove impurities and obtain a pure 2- (chloromethyl) -1 -methyl-1H -benzimidazole product. During extraction, select the appropriate extractant to separate the product and impurities in different phases; distillation is divided according to the boiling point of each component; recrystallization dissolves the product in a suitable solvent, cools down and crystallizes, and removes impurity to extract purity.
    1H - benzimidazole, 2 - (chloromethyl) -1 - methyl - What is the market outlook?
    Today, there are 2 - (chloromethyl) - 1 - methyl - 1H - benzimidazole, and its market prospect is related to many aspects.
    First of all, its use, this compound may have potential value in the field of medicine, can be used as an intermediate in drug synthesis, and can provide key raw materials for the creation of new drugs. Today's world attaches great importance to health, and the pharmaceutical market demand is always booming. If it goes well in drug research and development, it can take advantage of the vigorous development of the pharmaceutical industry and find a broad market space.
    Furthermore, in the field of materials science, it can be used to prepare special materials. With the advancement of science and technology, the search for new functional materials in the field of materials has never stopped. If its performance meets the needs of specific materials, such as unique optical and electrical characteristics, it can also be used in electronic and optical materials and other market segments.
    However, its market prospects also pose challenges. If the synthesis process is complex and expensive, it will restrict its large-scale production and promotion. And the market competition is quite fierce, and similar or alternative compounds may have occupied part of the market. If you want to stand out, you need to make great efforts in technological innovation and cost control.
    In summary, the market prospects for 2 - (chloromethyl) - 1 - methyl - 1H - benzimidazole present opportunities and challenges. Unemployed people can develop their skills with wisdom and hard work, or they can gain a place in the market.
    1H - benzimidazole, 2 - (chloromethyl) -1 - methyl - what are the precautions during use
    2 + (chloromethyl) -1 -methyl-1H -benzimidazole This substance has many points to pay attention to when using.
    First of all, it has a certain chemical activity, and the operation must be rigorous. Because it contains chloromethyl, it is prone to chemical reactions in case of specific reagents or conditions. In case of nucleophiles, the chlorine atoms of chloromethyl are easily replaced, resulting in impure products or uncontrolled reactions. Therefore, before use, it is necessary to know its reaction characteristics and possible reactions, and take comprehensive measures in advance.
    Furthermore, safety protection must not be taken lightly. This compound may be irritating and may cause damage to the skin, eyes and respiratory tract. When operating, wear appropriate protective equipment, such as laboratory clothes, gloves and goggles. In case of accidental contact, rinse with plenty of water immediately, and seek medical attention in a timely manner according to the specific situation.
    In addition, storage is also exquisite. It should be placed in a cool, dry and well-ventilated place, away from sources of fire and oxidants. Due to its chemical structure, improper storage or deterioration can affect the use effect and even cause safety accidents.
    During the retrieval process, accurate measurement is crucial. Because of the reaction involved, the dosage has a great impact on the reaction process and product purity. Therefore, it is necessary to measure with the help of precise instruments to ensure the accuracy and repeatability of experiments or production.
    At the same time, the ventilation conditions of the use place must be good. Avoid the accumulation of volatile gases and reduce potential hazards. And after use, the remaining materials and waste should be properly disposed of in accordance with relevant regulations and cannot be discarded at will to prevent environmental pollution.