As a leading 1H-Benzimidazole, 2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-, (R)- supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.
What is the chemical structure of 1H-Benzimidazole, 2- [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -, (R) -
(R) 2- [[[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] sulfinyl] -1H-benzimidazole, its chemical structure is as follows:
The core structure of this compound is a benzimidazole ring, the hydrogen at 1 position is unsubstituted, and the 2 position is connected to a sulfinyl group. The sulfur atom of the sulfinyl group is connected to a [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] group. Specifically, the 3-position of the pyridine ring has a methyl group, the 4-position is connected with a 2,2,2-trifluoroethoxy group, the 2-position of the pyridine ring is connected to a methylene group, the methylene group is connected to a sulfinyl group, and the sulfinyl group is connected to the 2-position of the benzimidazole ring.
The benzimidazole ring is formed by fusing a benzene ring with an imidazole ring, which has certain aromatic properties and unique chemical properties. The pyridine ring is also aromatic. The introduction of trifluoroethoxy gives the molecule specific electronic effects and physical and chemical properties. The presence of methyl groups also affects the spatial structure and chemical activity of the molecule. The structure of the whole compound determines its properties in chemical reactions and biological activities.
What are the physical properties of 1H-Benzimidazole, 2- [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -, (R) -
(R) -2 - [[3-methyl-4- (2,2,2-trifluoroethoxy) -2 -pyridyl] methyl] sulfinyl] -1H -benzimidazole, the physical properties of this substance are as follows:
Its appearance is often white to off-white crystalline powder, with a certain degree of stability, when encountering specific chemical substances such as strong oxidants, strong acids, and strong bases, or in extreme environments such as high temperature and high humidity, chemical reactions may occur, causing changes in its structure and properties.
The melting point has been experimentally determined to be about 132-134 ° C. This property can be used to identify the substance and serve as an important reference in its separation and purification process.
In terms of solubility, it has a certain solubility in organic solvents such as methanol, ethanol, and dichloromethane, but its solubility in water is relatively small. This difference in solubility can provide a basis for the design of its extraction, purification, and preparation processes.
Density is also one of its important physical properties. After measurement, it is about [X] g/cm ³. This value is of guiding significance for material accounting, storage, and transportation.
In addition, the substance has a certain sensitivity to light and heat, and light or long-term heat exposure may cause it to decompose or deteriorate. Therefore, when storing and using, it should be protected from light and stored at low temperature to maintain the stability of its chemical structure and properties, so that it can effectively play a role in medicine and other related fields.
What is the main use of 1H-Benzimidazole, 2- [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -, (R) -
(R) 2- [[[3-methyl-4 - (2,2,2-trifluoroethoxy) - 2-pyridyl] methyl] sulfinyl] -1H-benzimidazole, the main use of this substance is extraordinary. In the field of medicine, it can be called a good medicine for the world. It can be used as a proton pump inhibitor for the treatment of gastric acid-related diseases, such as gastric ulcers, duodenal ulcers and reflux esophagitis. Gain can effectively inhibit gastric acid secretion, acting as a strong barrier, blocking the erosion of gastric acid on the lining of the stomach and intestines, helping patients relieve pain and regain health.
In the pharmaceutical industry, it is also a key raw material. With its unique chemical structure and fine craftsmanship, it can synthesize many drugs with excellent curative effects, promoting the progress of medical science and technology. And in related research fields, it provides important tools and foundations for researchers to explore the mechanism of gastric acid secretion and develop new drugs. It is like the key to opening the door to the mystery of medicine, helping scientific research to move forward and making extraordinary contributions to human health and well-being.
What are the synthesis methods of 1H-Benzimidazole, 2- [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -, (R) -
The synthesis method of (R) - 2 - [ [ [ 3 - methyl - 4 - (2,2,2 - trifluoroethoxy) - 2 - pyridyl] methyl] sulfinyl] - 1H - benzimidazole is an important matter in organic synthesis. The methods are diverse and each has its own subtlety.
First, specific pyridine derivatives and sulfur-containing reagents can be carefully reacted through meticulous reaction steps to carefully control the reaction conditions, such as temperature, pH, reaction time, etc., to cleverly construct sulfinyl connections, and then achieve the integration of key structural fragments in the target molecule. In this process, it is necessary to precisely control the purity and ratio of the reagent. If there is a slight difference, it is easy to cause side reactions to breed and affect the purity and yield of the product.
Second, using benzimidazole as the starting material, through a series of orderly substitution reactions, pyridyl and sulfinyl groups are gradually introduced. This path requires a thorough understanding of the reaction sequence and reagent activity. Which group is introduced first and which step is followed by the reaction needs to be considered. For example, the introduction of some groups is not timely, which may make subsequent reactions difficult or cause unnecessary isomerization.
Third, there is also a synthesis strategy using transition metal catalysis. Transition metal catalysts can effectively promote the formation of various chemical bonds and precisely guide the formation of target products. However, this method requires quite high requirements on the choice of catalyst, dosage and the creation of an inert atmosphere in the reaction system. The activity and selectivity of the catalyst will have a significant impact on the reaction process and results.
Although these various synthesis methods have their own advantages, they all require the experimenter to be in awe, with a rigorous attitude and exquisite skills, in order to move forward smoothly in the synthesis and obtain the ideal product.
1H-Benzimidazole, 2- [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridinyl] methyl] sulfinyl] -, (R) - What are the relevant safety precautions?
(R) -2 - [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] sulfinyl] -1H-benzimidazole, which is the chemical name of rabeprazole. When it comes to safety precautions related to it, just like the ancients had to follow various rules carefully, there are also many points to pay attention to.
At the operational level, do not be careless. Because it is a chemical substance, when operating in a laboratory or production environment, the process should be strictly controlled like the ancients concocted medicinal pills. Be sure to wear appropriate protective equipment, such as protective gloves, goggles and lab clothes, to prevent it from coming into contact with the skin and eyes. If it is accidentally contaminated, it may enter the body as a poison and cause discomfort. The operating environment should also be well ventilated to avoid the accumulation of volatile gases. If you inhale too much, or cause damage to the respiratory tract, it is like turbid gas entering the lungs and harming the body.
Storage should also be extra careful. It should be stored in a cool, dry and well-ventilated place, away from fire and heat sources, just like the ancients hid precious things in a safe place. At the same time, it should be stored separately from oxidants, acids, etc., and must not be mixed. Otherwise, it may meet with ice and fire, causing dangerous reactions.
During transportation, do not take it lightly. It needs to be properly packaged in accordance with relevant regulations to ensure that it is not affected by bumps and collisions during transportation, just like escorting important envoys, it must be thorough.
In addition, when using this substance for related research or production, the operator needs to have professional knowledge and skills, and can only be hired after professional training, just like the ancients who needed to be carefully taught by the master and passed the assessment. In this way, they can use (R) -2 - [[3-methyl-4- (2,2,2-trifluoroethoxy) -2-pyridyl] methyl] sulfinyl] -1H-benzimidazole to ensure their own safety and smooth operation.
