1H-Benzimidazole-1-butanoic acid

The chemical structure of 1H-benzimidazole-1-butyric acid is formed by linking a benzimidazole ring to a side chain of butyric acid. The benzimidazole ring is a fused heterocyclic ring containing two nitrogen atoms, composed of a benzene ring and an imidazole ring. This ring has aromatic properties and gives the compound unique physical and chemical properties. At position 1, the side chain of butyric acid is connected. The side chain of butyric acid is a straight chain fatty acid structure containing four carbon atoms, with a carboxyl group at one end (-COOH), which gives the compound acidic properties and can participate in many chemical reactions, such as salt formation reactions, esterification reactions, etc. In this structure, the nitrogen atom of the benzimidazole ring can provide lone pairs of electrons, exhibit certain alkalinity, and can interact with acids or metal ions. Overall, the chemical structure of 1H-benzimidazole-1-butyric acid fuses the properties of the benzimidazole ring and the function of the side chain of butyric acid, making it potentially useful in organic synthesis, pharmaceutical chemistry, etc. It can be used as a lead compound to develop drugs with specific biological activities, or as a basic unit for building materials with special structures and properties in materials science.

1H-benzimidazole-1-butyric acid, this is an organic compound. Its physical properties are as follows:
Viewed at room temperature, it is mostly white to light yellow crystalline powder, which is easy to identify and can be preliminarily distinguished in laboratory or industrial scenes.
Smell, the compound usually has a slight odor, no strong pungent or special odor, and this property has little impact on the environment and personnel's sense of smell during operation and use.
When it comes to solubility, it shows a certain solubility in organic solvents such as ethanol and dichloromethane. Ethanol, as a common organic solvent, has a good degree of mutual solubility with it, and can also be moderately dissolved in dichloromethane. However, in water, the solubility is relatively low. This difference in solubility is crucial in the separation, purification and choice of reaction medium of the compound.
Melting point is experimentally determined to be in a specific temperature range. The exact melting point data varies slightly due to the purity of the compound and the test conditions, generally around [X] ° C. The determination of the melting point provides a key basis for the identification of the purity and characteristics of the compound.
Its density is also an important physical property. Under specific conditions, the density is about [X] g/cm ³. Density information is indispensable in the fields of compound metrology, mixing and engineering design. The above physical properties are of great significance in the research, production and application of 1H-benzimidazole-1-butyric acid, providing basic data and theoretical support for related operations and reactions.

1H-benzimidazole-1-butyric acid, this is an organic compound. Its common uses involve medicine, chemical industry and other fields.
In the field of medicine, it is often used as a raw material for drug synthesis. Because of its specific chemical structure and activity, it can provide a key skeleton for drug creation. For example, through chemical modification and modification, new compounds with specific pharmacological activities can be obtained, or have antibacterial, antiviral, anti-tumor and other effects, which can help the development of new drugs.
In the field of chemical industry, it also has important uses. It can be used as an intermediate in organic synthesis and participates in the synthesis of a variety of fine chemicals. Due to its unique structure, it can react with many reagents to generate materials with different functions. Like in the preparation of polymer materials, or can participate in the polymerization reaction, endowing the material with special properties, such as improving the thermal stability and mechanical properties of the material.
Furthermore, in scientific research and exploration, it is an important research object. By studying its physical and chemical properties, reaction mechanisms, etc., scientists can deeply understand the characteristics and reaction laws of organic compounds, contribute to the development of organic synthetic chemistry, and promote theoretical and technological progress in related fields.
In short, although 1H-benzimidazole-1-butyric acid is an organic compound, it plays an important role in medicine, chemical industry and scientific research. It has a wide range of uses and promising prospects.

The method of synthesizing 1H-benzimidazole-1-butyric acid has been around for a long time and has various methods.
One is to use o-phenylenediamine and succinic acid as raw materials. The two are heated at high temperature in a suitable solvent in an appropriate ratio. The amino group of o-phenylenediamine interacts with the carboxyl group of succinic acid through a condensation reaction to form an intermediate product. After the cyclization reaction, the final product is 1H-benzimidazole-1-butyric acid. In this process, the choice of solvent is quite critical, such as glacial acetic acid, which can not only dissolve the raw material but also help the reaction to proceed. Temperature control is also indispensable, usually between 150 ° C and 200 ° C, so that the reaction can occur smoothly.
Second, phthalic anhydride and succinic anhydride can be used as starting materials. Succinic anhydride is more reactive than succinic acid. When phthalic anhydride and succinic anhydride are placed in a specific reaction environment, the two react rapidly. The carbonyl group of succinic anhydride reacts with the amino group of phthalic anhydride to form an amide-like structure. Subsequently, under appropriate conditions, further cyclization is formed to form the target product. This reaction can often be carried out under milder conditions, and the temperature may be controlled at 100 ° C - 150 ° C. And due to the high reactivity of succinic anhydride, the reaction rate is faster, which can shorten the reaction time.
Third, the method of using o-nitroaniline as raw material. First, o-nitroaniline is converted into o-phenylenediamine through reduction reaction. Commonly used reducing agents include iron powder, sodium sulfide, etc. After obtaining o-phenylenediamine, it is reacted with succinic acid or succinic anhydride according to the above method to obtain 1H-benzimidazole-1-butyric acid. Although this route is a little complicated, o-nitroaniline has a wide range of sources and may have advantages in cost.
All these synthesis methods have their own advantages and disadvantages. In practical application, it is necessary to choose carefully according to the availability of raw materials, cost, difficulty of reaction conditions and many other factors, in order to achieve the purpose of synthesis.

I have not heard of the exact price range of "1H - Benzimidazole - 1 - butanoic acid" in the market. This is a chemical substance, and its price often varies for many reasons. First, purity is the key factor. If the purity is very high, almost scientific research grade, the price will be high; if it is only a lower purity commonly used in industry, the price will be relatively low. Second, the market supply and demand situation also has an impact. If demand is strong and supply is limited, the price may rise; conversely, if supply exceeds demand, the price may fall. Third, the ease of production and acquisition also affects the price. If the preparation requires complex processes and high costs, the price must be high; if the preparation is relatively simple, the price may be close to the people. Fourth, the difference between sellers, such as factory direct sales, or through multi-level agents, the price will also be different. Factory direct sales or more affordable, and through multi-level agents, due to layers of price increases, the price or higher. Therefore, to know the exact price range, when consulting chemical product suppliers in detail, or carefully checking the recent trading conditions on the chemical product trading platform, a more accurate price range can be obtained.