1H-Benzimidazole, 1-(2-ethoxyethyl)-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-, (E)-2-butenedioate (1:2)

This is the chemical structure analysis of 1- (2-ethoxyethyl) -2- (hexahydro-4-methyl-1H-1,4-diazepine-1-yl) -1H-benzimidazole (E) -2-butene diester (1:2).
Looking at this chemical name, it can be disassembled and analyzed. 1H-benzimidazole is the core structure, which is a nitrogen-containing heterocyclic compound with a unique conjugate system. The first position is connected with 2-ethoxyethyl, which is connected by ethoxy and ethyl to increase the hydrophilicity and steric resistance of the molecule. The second position is connected with hexahydro-4-methyl-1H-1,4-diazepine-1-yl, which is also a nitrogen-containing heterocyclic ring. The substitution of 4-methyl gives the ring structure specific spatial and electronic effects.
Furthermore, (E) -2-butenedioate (1:2) shows that the compound forms salts with 2-butenedioic acid of the (E) configuration in a ratio of 1:2. (E) The configuration determines the spatial arrangement of groups on both sides of the double bond, which affects the physical and chemical properties of the molecule.
The overall structure of this compound and the interaction of its parts give it unique chemical activity and physical properties. It may have potential application value in pharmaceutical chemistry, organic synthesis and other fields. It can participate in specific chemical reactions or biological activity processes due to the characteristics of each group.

1 - (2 - ethoxyethyl) - 2 - (hexahydro - 4 - methyl - 1H - 1,4 - diazepine - 1 - yl) - 1H - benzimidazole (E) - 2 - butenedioic acid (1:2) salt This salt has many physical properties. Its properties may be solid, due to the molecular structure containing complex organic groups, the intermolecular force is strong, and it tends to be solid at room temperature and pressure.
Looking at its solubility, there are hydrophilic parts such as ethoxy groups in the molecule, but the overall organic structure is huge, and the solubility in water may be limited. It is slightly soluble in polar organic solvents, such as ethanol, acetone, etc. Due to the principle of similar phase dissolution, some polar groups interact with organic solvents.
When it comes to melting point, due to the existence of rigid structures such as benzimidazole and diazepines in the molecular structure, the molecules are closely arranged, the intermolecular force is large, and the melting point is high, or it is in the range of 150 ° C to 250 ° C.
When it comes to stability, the benzimidazole ring and diazepine ring in the molecular structure are relatively stable. However, there are carbon-carbon double bonds in the allene acid part, which can cause structural changes under extreme conditions such as strong oxidants and high temperatures, or reactions such as oxidation and addition. Its stability is also affected by pH. In acidic or alkaline environments, some groups may protonate or deprotonate, which affects the overall stability.

1 - (2 - ethoxyethyl) - 2 - (hexahydro - 4 - methyl - 1H - 1,4 - diazepine - 1 - yl) - 1H - benzimidazole (E) - 2 - butene diester (1:2), this substance is commonly used in medicine stones raw materials. It is used in medicine and medicine for the treatment of diseases.
The way of viewing medicine stones requires distinguishing the properties of various medicines and using them in combination to achieve the effect of removing diseases. The ingredients of this medicine have been studied by prescriptions and are useful in the treatment of a variety of diseases. For example, if the viscera is not in harmony, and the qi and blood are not smooth, the doctor may take this material into the prescription and use its characteristics to adjust the viscera, clear the qi and blood.
Or in some arthralgia, disease, or based on this, other drugs are prepared. Because it can connect the meridians and collaterals, adjust the health, and help the human body recover righteousness, it is often an important choice in the doctor's technique of treating and saving people. The preparation method also needs to be prepared according to the ancient method and operated carefully, so as to ensure the good effect of the medicine and help the sick in the world.

To prepare 1H - benzimidazole, 1- (2 - ethoxyethyl) - 2- (hexahydro - 4 - methyl - 1H - 1,4 - diazepine - 1 - yl) -, (E) - 2 - butene diester (1:2), the method is as follows:
First take an appropriate amount of 1- (2 - ethoxyethyl) - 2 - halogenated benzimidazole, place it in a clean reactor, dissolve it in an organic solvent, the selected solvent must have good solubility and stability, such as dichloromethane, N, N-dimethylformamide and the like.
Slowly add hexahydro-4-methyl-1H-1,4-diazepine to the kettle in an appropriate proportion, and add an appropriate amount of acid binding agent, such as potassium carbonate, triethylamine, etc., to neutralize the hydrogen halide generated by the reaction to promote the forward reaction. The reaction temperature should be controlled in a moderate range, and the constant temperature can be maintained in an oil bath or a water bath. The common temperature range is about 50-80 degrees Celsius. The reaction lasts for several hours. During this period, stir at a constant speed with a stirrer to fully contact the reactants.
After the reaction is completed, the products are separated by vacuum distillation or extraction. If extraction is used, select a suitable extractant, such as ethyl acetate, ether, etc., after multiple extractions, combine the organic phases, and then dry them with anhydrous sodium sulfate to remove the moisture.
After that, take the obtained product and (E) -2 -butenedioic acid in a ratio of 1:2, place it in another reaction vessel, add an appropriate amount of catalyst, such as p-toluenesulfonic acid, and react at a suitable temperature. This temperature may be between 80 and 100 degrees Celsius for a number of reaction times.
At the end of the reaction, the product is purified by recrystallization, and a suitable solvent is selected, such as a mixed solvent of ethanol, acetone and water, to obtain high-purity 1H-benzimidazole, 1- (2-ethoxyethyl) -2- (hexahydro-4-methyl-1H-1,4-diazepine-1-yl) -, (E) -2-butene diester (1:2). Be sure to pay attention to safety during operation and follow chemical experimental specifications to prevent accidents.

1H-benzimidazole, 1- (2-ethoxyethyl) - 2- (hexahydro-4-methyl-1H-1,4-diazepine-1-yl) -, (E) - 2-butene diester (1:2) This substance is a safety risk. Looking at the name of this substance, it has a complex structure and is composed of a combination of various groups. Gu Yun: "Those who are abnormal in things must be different." This complex structure may cause its special properties, and the specific ratio of (E) -2-butenediate is (1:2). This ratio may have a significant impact on its properties and reactivity.
Complex structures are prone to change when synthesized, stored and used with a little carelessness. During the synthesis process, the reaction conditions of each group may need to be precisely controlled, otherwise it is prone to side reactions and impure products. During storage, or due to environmental temperature, humidity, light and other factors, decomposition, deterioration, etc. When used, if the nature is not understood enough, mixed with other substances, or reacted violently, endangering personal and environmental safety.
Furthermore, although the specific use of this substance is not known in detail, the complex structure often implies that it is used in a specific field, and the use in a specific field often requires strict regulations and procedures. If there is a slight mistake, the safety risk will rise sharply. Therefore, this substance should be treated with caution, carefully investigate its nature and use, and strictly abide by the operating norms to avoid safety risks.