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What is the chemical structure of 1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl?
1-Methyl-5-amino-1H-benzimidazole-2-ethyl butyrate, its chemical structure can be analyzed as follows.
The core of this compound is a benzimidazole ring, which is formed by fusing a benzene ring with an imidazole ring. At position 1, there is a methyl group connected to the carbon at position 1 of the benzimidazole ring by a single bond, which is an alkyl substituent and affects the physical properties of the molecule such as lipophilicity.
There is an amino group at position 5, and the amino group is connected to the carbon at position 5 of the benzimidazole ring by a single bond. The amino group has a certain alkalinity and can participate in many chemical reactions and contribute greatly to the chemical activity of the molecule.
At the second position of the benzimidazole ring, the structural fragment of ethyl butyrate is connected. The ethyl butyrate part first has a carbon chain of butyric acid, which is a straight chain structure of four carbons from the connection with the benzimidazole ring, and the carbon on this carbon chain is connected in sequence by a single bond. The end of the carbon chain is connected to an ethyl ester group. In the ethyl ester group, the carboxyl group is esterified with ethanol to form an ester bond, that is, the -COOCH ² CH 🥰 structure. The existence of this ester group also affects the properties of the whole molecule, such as solubility and stability.
Overall, the chemical structure of 1-methyl-5-amino-1H-benzimidazole-2-ethyl butyrate is composed of benzimidazole rings and substituents at different positions. Each part interacts to determine the unique physical and chemical properties of the compound.
What are the main uses of 1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl?
1-Methyl-5-amino-1H-benzimidazole-2-ethyl butyrate, an organic compound. Its main uses are quite extensive, in the field of medicine, often used as an intermediate for drug synthesis. The structure of benzimidazole is quite common in many active ingredients of drugs. With this compound, it can be chemically converted to construct molecular structures with specific pharmacological activities to develop new drugs or optimize the properties of existing drugs.
In the chemical industry, it also plays an important role. It can be used as a raw material for the synthesis of functional materials and used to prepare polymer materials with special properties. Due to its structure containing specific functional groups, it can participate in polymerization reactions, etc., giving the material unique properties, such as improving the stability and solubility of the material.
Furthermore, in the study of organic synthetic chemistry, this compound is a commonly used starting material. Scientists design and carry out various organic reactions with its structural properties to explore new synthesis methods and strategies, and contribute to the development of organic chemistry. Chemists can use the reactivity of amino groups, ester groups and other functional groups to carry out substitution, addition and other reactions to expand the structural diversity of organic molecules, and then lay the foundation for more applications in the field.
What are the physical properties of 1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl
1-Methyl-5-amino-1H-benzimidazole-2-ethyl butyrate, this is an organic compound. Its physical properties are crucial, related to its performance in various scenarios.
Looking at its properties, it is mostly white to quasi-white crystalline powder under normal circumstances, with fine texture. This form is conducive to uniform dispersion in many chemical reactions and effective participation in the reaction process.
Melting point is also an important property, usually in a specific temperature range, between about [X] ° C and [X] ° C. The melting point range is the inherent property of this compound and can be used for purity identification. If the purity is high, the melting point will be in a stable range.
The solubility is also not to be underestimated. It exhibits good solubility in common organic solvents such as ethanol and dichloromethane, and can be easily dissolved to form a uniform solution, which provides convenience for its treatment as a reactant or product in organic synthesis operations; while in water, the solubility is relatively limited and only slightly soluble. This property is related to the existence of hydrophobic groups in the molecular structure.
In addition, its density also has a certain value, about [X] g/cm ³. This density value is of great significance in the process of material separation and mixing. According to this characteristic, this compound can be separated or mixed with other substances by specific methods.
In summary, the physical properties of 1-methyl-5-amino-1H-benzimidazole-2-ethyl butyrate, such as properties, melting point, solubility, density, etc., play a decisive role in its application in chemical research, industrial production and other fields. In-depth understanding of these properties can make better use of this compound.
What are the synthesis methods of 1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl
The synthesis method of 1-methyl-5-amino-1H-benzimidazole-2-ethyl butyrate, although the classic "Tiangong Kaiwu" does not directly describe the synthesis method of this specific compound, it can use the chemical process wisdom contained in it to find relevant ideas.
In ancient chemical processes, material selection is quite critical. To make this substance, it is necessary to choose a suitable starting material. For example, a substance with benzimidazole structure can be found as a base, or a raw material that can be reacted to construct this structure, such as a specific aromatic hydrocarbon and a nitrogen-containing reagent, to combine the parent nucleus of benzimidazole.
The reaction steps of ancient chemistry are often based on experience and observation. Analogous ancient chemical reaction, or first make aromatic hydrocarbons and nitrogen react under suitable conditions, such as heating, with a specific solvent to help dissolve, to promote the formation of benzimidazole ring. To obtain the parent of benzimidazole, then introduce methyl and amino groups. The introduction of methyl groups can be achieved by substitution reaction with methyl-containing reagents under suitable catalysts or conditions. The introduction of amino groups, or select suitable nitrogen-containing reagents, and find an appropriate reaction path according to the reactivity and selectivity.
Synthesis of ethyl butyrate moiety, or first make butyric acid, with the corresponding carboxylic acid and alcohol as raw materials, and esterification reaction. Then connect the ethyl butyrate moiety to the benzimidazole structure. This step may require finding suitable linking reagents and reaction conditions to ensure that the two effectively combine without damaging other groups.
During the reaction process, temperature and time are very important. Although the ancient method did not have precise instruments, it was timed according to the heat and experience. To synthesize this compound, it is necessary to explore many times to find the appropriate reaction temperature and time, so that the reaction is sufficient and the product is not damaged due to overreaction. And the reaction environment is also affected, or it is necessary to ensure the smooth reaction and the purity of the product under specific pH, inert atmosphere and other conditions.
1-Methyl-5-amino-1H-benzimidazole-2-butanoic acid ethyl in storage and transportation
1-Methyl-5-amino-1H-benzimidazole-2-ethyl butyrate is a fine chemical, and many points must be paid attention to when storing and transporting.
First of all, store this substance in a cool and dry place. Because the cool environment can reduce the risk of biochemical reactions due to excessive temperature, dry conditions can avoid moisture hydrolysis. If the storage environment humidity is too high, moisture can easily interact with the substance, causing structural changes and damaging quality. And it should be stored in a well-ventilated place, so as to prevent the accumulation of volatile gases and reduce safety hazards. At the same time, it is necessary to strictly keep away from fire and heat sources. This substance may be flammable and may cause combustion or even explosion in case of open flames and hot topics. It also needs to be stored separately from oxidants, acids, alkalis, etc. Because of its active chemical properties, contact with these substances can easily trigger chemical reactions and lead to deterioration.
As for transportation, it is necessary to ensure that the packaging is complete and well sealed. If the packaging is damaged, the substance may leak, pollute the environment, and may also cause harm to transportation personnel. During transportation, the speed of the vehicle should not be too fast to prevent bumps and vibrations from causing damage to the packaging. And the transportation vehicle should be equipped with the corresponding variety and quantity of fire equipment and leakage emergency treatment equipment. In the event of an accident, it can be responded to in time. In addition, transport personnel need to be professionally trained, familiar with the characteristics of the substance and emergency response methods, pay close attention to the status of the goods during transportation, and take immediate measures if there is any abnormality. In short, the storage and transportation of 1-methyl-5-amino-1H-benzimidazole-2-ethyl butyrate must be treated with caution and strictly followed to ensure safety.