1-methyl-1H-imidazole-4-sulfonyl chloride

1-Methyl-1H-imidazole-4-sulfonyl chloride is an important compound in organic chemistry. Its physical properties are particularly critical and it is widely used in various fields of chemical industry.
First of all, under normal conditions, 1-methyl-1H-imidazole-4-sulfonyl chloride is mostly white to quasi-white crystalline powder. This form is easy to store and transport, and it is also convenient in many chemical reactions.
times and melting point, its melting point is about within a specific range, and the melting point value is of great significance for identifying this compound and controlling the related reaction process. Accurate melting point determination can provide an important basis for determining its purity. With high purity, the melting point is often closer to the theoretical value.
Furthermore, when it comes to solubility, 1-methyl-1H-imidazole-4-sulfonyl chloride can be soluble in several organic solvents, such as dichloromethane, chloroform, etc. This solubility property makes it possible to effectively participate in the reaction as a reactant or intermediate in a specific organic reaction system. And because of its different solubility in different solvents, it also helps to select suitable solvent systems in the separation and purification process.
Stability is also mentioned. Under normal temperature and dry environment, 1-methyl-1H-imidazole-4-sulfonyl chloride has certain stability. When exposed to water or humid air, hydrolysis is prone to occur, which requires special attention during storage and use. Due to the activity of sulfonyl chloride groups in its chemical structure, it is more sensitive to environmental factors, and humid environments are prone to structural changes, affecting its chemical properties and application effects. The physical properties of 1-methyl-1H-imidazole-4-sulfonyl chloride, such as its properties, melting point, solubility and stability, play a decisive role in its application in organic synthesis, drug development and other fields, and cannot be ignored in chemical production practice and scientific research.

The chemical synthesis method of 1-methyl-1H-imidazole-4-sulfonyl chloride covers multiple paths. One method is to take 1-methyl-1H-imidazole as the starting material and react with an appropriate sulfonating agent, such as fuming sulfuric acid or chlorosulfonic acid. Under low temperature and temperature control conditions, slowly drop the sulfonating agent into the reaction vessel containing 1-methyl-1H-imidazole. This process needs to be fully stirred to make the reaction uniform. After the reaction is completed, 1-methyl-1H-imidazole-4-sulfonic acid can be obtained through appropriate separation and purification steps, such as reduced pressure distillation, recrystallization, etc.
Then, the chlorination reagent, such as thionyl chloride or phosphorus oxychloride, is reacted with 1-methyl-1H-imidazole-4-sulfonic acid. This reaction often requires the addition of a small catalyst, such as N, N-dimethylformamide (DMF), to facilitate the reaction. Under the conditions of heating and reflux, the reaction continues for a period of time. After the reaction is completed, the excess chlorinated reagent is evaporated, and then purified by reduced pressure distillation, column chromatography, etc., to obtain 1-methyl-1H-imidazole-4-sulfonyl chloride.
Another method is to use 4-halo-1-methyl-1H-imidazole as raw material to react with sulfites, such as sodium sulfite or potassium sulfite, in an appropriate solvent to obtain 1-methyl-1H-imidazole-4-sulfonic acid intermediate. After the oxidation step, it is oxidized to 1-methyl-1H-imidazole-4-sulfonic acid with a suitable oxidizing agent, such as hydrogen peroxide or sodium periodate. The subsequent steps are treated with chlorination reagents as before, and the target product is purified. The process of synthesis, the precise control of reaction conditions at each step, the proper preparation of material proportions, and the reasonable choice of purification steps are all related to the purity and yield of the product, and must be done with caution.

1 - methyl - 1H - imidazole - 4 - sulfonyl chloride (1 - methyl - 1H - imidazole - 4 - sulfonyl chloride) is useful in various fields.
In the field of medicine, it can be the key raw material for synthesizing wonderful medicines. The structure of Gainimidazole is common in many active pharmaceutical ingredients, and the activity of sulfonyl chloride groups is quite strong. It can be conjugated with other compounds through delicate chemical reactions to form new drugs with specific pharmacological activity. Or as an antibacterial drug, it can inhibit the growth of pathogens; or as an anti-cancer agent, it can block the proliferation of tumors and seek well-being for human health.
As for the field of material chemistry, it also has extraordinary functions. It can be used to create polymer materials with special properties. By reacting with monomers containing active hydrogen or unsaturated bonds, polymers with unique molecular structures can be constructed. These polymers may have excellent thermal stability and can be used in materials in high temperature environments; or have good ionic conductivity, which has emerged in battery electrolyte materials and promoted the progress of materials science.
Furthermore, in the field of organic synthesis, 1-methyl-1H-imidazole-4-sulfonyl chloride is a powerful tool. Due to its ease of conversion of sulfonyl chloride functional groups, imidazole sulfonyl groups can be introduced through various reactions such as substitution and condensation, which adds unique structures and properties to target compounds, expands the way of organic synthesis, and helps synthetic chemists create more novel and valuable organic molecules.

1-Methyl-1H-imidazole-4-sulfonyl chloride is a chemical substance, and its storage conditions are crucial. This substance should be placed in a cool, dry and well-ventilated place. Cover because of its active nature, easy to react with water, moisture, etc., so it is necessary to ensure that the storage environment is dry.
Storage temperature is also particular. Generally speaking, it should be controlled at a low temperature, usually 2-8 ° C. This temperature range can slow down its chemical reaction rate and make its chemical properties more stable. If the temperature is too high, it may cause decomposition or other adverse chemical changes.
Furthermore, this substance needs to be sealed and stored. Because it is easy to interact with the components in the air, sealing can prevent it from excessive contact with the air, thereby maintaining its purity and stability. In the choice of storage containers, corrosion-resistant materials should be used to prevent the container from reacting with the substance and affecting its quality.
It should be noted that the storage place should be kept away from fire sources, heat sources and oxidants. 1-methyl-1H-imidazole-4-sulfonyl chloride may cause dangerous chemical reactions, such as combustion, explosion, etc., which endanger the safety of the storage environment. Therefore, following these storage conditions can ensure the quality and storage safety of the substance.

I look at this "1-methyl-1H-imidazole-4-sulfonyl chloride", which is a chemical product, and the Chinese name may be "1-methyl-1H-imidazole-4-sulfonyl chloride". As for its market price, it is difficult to determine. The price of the cover is often affected by many factors, such as the price of raw materials, the difficulty of preparation, the supply and demand situation, the difference in quality, and even the change of seasons and regions, which can cause its price to fluctuate.
Looking at the "Tiangong Kaiwu" in the past, although the various process products were described in detail, the chemistry at that time was not as prosperous as it is today, and the price of this product was not involved. Today is different from the past, the chemical industry is developed, and this chemical reagent is in the market. If the quality is ordinary and the quantity is quite abundant, its price may be relatively easy; if the quality is excellent, and the preparation is difficult, or if it is specially made for a specific purpose, its price should be high.
As far as I know, the price of similar chemical reagents may vary widely due to differences in purity. For low purity, it can cost from a few yuan to tens of yuan per gram; for high purity, it can reach 100 yuan or even higher per gram. However, "1-methyl-1H-imidazole-4-sulfonyl chloride", without more detailed information, it is difficult to estimate its exact price. It is generally necessary to ask chemical raw material merchants or refer to professional chemical trading platforms to obtain a more accurate price.