1 4 Nitrophenyl Sulfonyl 1h Benzimidazole
quinoline thiophene imidazole thiazole

1-[(4-nitrophenyl)sulfonyl]-1H-benzimidazole

    Specifications

    HS Code

    382167

    Chemical Formula C13H9N3O4S
    Molar Mass 303.294 g/mol
    Solubility In Water Expected to be low, as it has a relatively non - polar benzimidazole ring and a sulfonyl - substituted phenyl group
    Solubility In Organic Solvents May be soluble in common organic solvents like DMSO, DMF due to its organic nature
    Pka There are potentially acidic/basic sites; benzimidazole nitrogen can be basic, but exact pKa values require experimental determination
    Stability Stable under normal conditions, but may be sensitive to strong oxidizing or reducing agents
    Reactivity Can participate in reactions typical of benzimidazoles and sulfonyl - substituted aromatic compounds, such as nucleophilic substitution at the sulfonyl group

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    Frequently Asked Questions

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    What is the chemical structure of 1- [ (4-nitrophenyl) sulfonyl] -1H-benzimidazole
    1 - [ (4-thiazolyl) pyridyl] -1H-pyrrolido-pyridine compounds are a class of organic compounds with unique structures. Looking at its structure, 1H-pyrrolido-pyridine is used as the core parent ring. This parent ring is fused from pyrrole ring and pyridine ring, and has a unique conjugation system, which endows the compound with specific physical and chemical properties.
    In the first position of the parent ring, there is a substituent, which is [ (4-thiazolyl) pyridyl]. Thiazolyl is a five-membered heterocycle containing sulfur and nitrogen, which has certain aromatic and biological activities; pyridyl is a six-membered heterocycle containing nitrogen, which also has unique electronic effects and reactivity. After the two are connected, they are connected to the first position of 1H-pyrrolido-pyridine to form a complex and characteristic structure.
    The uniqueness of this structure makes this compound have potential applications in pharmaceutical chemistry, materials science and other fields. In pharmaceutical chemistry, such structures may exhibit biological activities such as antibacterial, anti-inflammatory, and anti-tumor due to their good interaction with specific biological targets; in materials science, their conjugated structures may give compounds special photoelectric properties, which can be used to prepare organic optoelectronic devices. < Br >
    However, the specific properties and applications still need to be clarified through rigorous experiments and studies. When synthesizing such compounds, the conditions and selectivity of each reaction step need to be considered to ensure the purity and yield of the target product.
    What are the physical properties of 1- [ (4-nitrophenyl) sulfonyl] -1H-benzimidazole
    1 - [ (4 -pyridyl) benzyl] -1H -indolocarbazole, this material has unique physical properties. Its color is often crystalline, the color may be white to light yellow, the powder is fine, and the quality is uniform.
    The melting point is quite high, which is a key physical characteristic. Due to intermolecular forces and structural stability, its melting point is in a specific range. In the field of materials science, its high melting point characteristics make it potentially used in high temperature environments, such as the preparation of electronic components and special composites under certain high temperature conditions.
    In terms of solubility, it shows a certain solubility in common organic solvents such as dichloromethane and N, N-dimethylformamide (DMF). The molecules of the organic solvent interact with the compound molecules. According to the principle of similarity dissolution, the degree of matching between structure and polarity determines the solubility. This property provides the possibility for its synthesis, purification and solution processing technology. During organic synthesis, the reactants can be dissolved with the help of suitable solvents to promote the reaction. In the preparation of materials, it can be processed in the solution system to form a uniform dispersion system, which lays the foundation for subsequent molding and performance regulation.
    Furthermore, it has certain photophysical properties. The electron conjugation system in the molecular structure is huge, and under the excitation of light, the electron transition produces a unique light absorption and emission phenomenon. Or it can fluoresce under the irradiation of specific wavelengths of light, and the fluorescence characteristics may make it have potential application in the fields of fluorescent probes, optical sensors, etc. It can respond to specific substances or environmental changes with fluorescence signals, achieving highly sensitive detection and analysis.
    What are the common synthesis methods of 1- [ (4-nitrophenyl) sulfonyl] -1H-benzimidazole
    The common synthesis methods of 1 - [ (4 -cyanobenzyl) bromobenzyl] -1H -indolocarbazole are mostly made by ingenious methods and various materials and conditions.
    First, the appropriate indole derivative is used as the starting material, and the specific halogenated benzyl compound can be connected by nucleophilic substitution reaction under a suitable base and solvent environment. In this process, the type and dosage of bases, the polarity of the solvent, the boiling point, etc., all have a great influence on the reaction process and yield. If a moderately basic base such as potassium carbonate is selected, and a solvent with suitable polarity such as acetonitrile is selected, and the temperature is controlled at a certain range, the effect may be better.
    Second, the indole ring can be modified first, and specific substituents can be introduced to change its electron cloud density and reactivity. Then, it reacts with specially treated (4-cyanobenzyl) bromobenzyl derivatives under the action of catalysts. Among them, the activity and selectivity of the catalyst are very critical, and it needs to be carefully selected, such as some transition metal catalysts, which may accelerate the reaction and improve the selectivity of the target product.
    Third, it can also be synthesized by multi-step series reaction method. First, the basic skeleton of indole-carbazole is constructed through several steps of reaction, and then the (4-cyanobenzyl) bromobenzyl structure is introduced in suitable steps. Although there are many steps in this approach, if the reaction conditions of each step are precisely controlled, the intermediate product is properly separated and purified, and the target product can be efficiently obtained. Each step of the reaction requires careful adjustment of reaction parameters, such as reaction time, temperature, and reactant ratio, according to the characteristics of the reactants and products, in order to achieve the ideal synthesis effect.
    In which fields is 1- [ (4-nitrophenyl) sulfonyl] -1H-benzimidazole used?
    1- [ (4-aminophenyl) sulfonyl] -1H-benzimidazole has applications in many fields such as medicine, agriculture, and materials. The details are as follows:
    - ** Pharmaceutical field **: Such compounds have diverse biological activities. One is anti-tumor activity, which can inhibit tumor growth by inhibiting tumor cell proliferation and inducing tumor cell apoptosis. As some studies have shown, 1- [ (4-aminophenyl) sulfonyl] -1H-benzimidazole derivatives with specific structures can precisely act on specific targets in tumor cells and interfere with tumor cell signaling pathways, thus exhibiting good anti-tumor effects. The second is antibacterial activity, which can destroy bacterial cell walls, cell membranes or interfere with bacterial nucleic acid synthesis, etc., and has inhibitory or killing effects on a variety of bacteria. It can be used to develop new antibacterial drugs to deal with the increasingly serious bacterial resistance problem. The third is anti-inflammatory activity, which can regulate the release and expression of inflammatory mediators in the body, reduce inflammatory response, and provide new strategies for the treatment of inflammation-related diseases.
    - ** Agricultural field **: Can be used as a pesticide. On the one hand, it has inhibitory effects on plant pathogens, can prevent and treat a variety of plant diseases, and ensure crop yield and quality. For example, it has a significant inhibitory effect on the growth and reproduction of common fungal diseases, such as wheat rust, cucumber powdery mildew, and other pathogens. On the other hand, some of these compounds also have certain insecticidal activities, which can act on the nervous system or physiological and metabolic processes of pests to achieve the purpose of pest control.
    - ** Material Field **: 1- [ (4-aminophenyl) sulfonyl] -1H -benzimidazole can be used to prepare functional polymer materials. Because of the presence of special groups such as benzimidazole ring and sulfonyl group in its structure, it can endow the material with unique properties. If it is introduced into a polymer, it can improve the thermal stability, mechanical properties and chemical stability of the material. In the fields of aerospace, electronics and electrical appliances, the material properties are strictly required, and such functional polymer materials have broad application prospects. At the same time, the compound can also be used to prepare materials with special adsorption properties, selectively adsorb specific metal ions or organic molecules, and play a role in environmental monitoring and pollutant treatment.
    What is the market outlook for 1- [ (4-nitrophenyl) sulfonyl] -1H-benzimidazole?
    1- [ (4-cyanobenzyl) carboxyl] -1H-indolopyridine is a class of promising organic compounds. Its market prospects are related to many aspects.
    As far as the pharmaceutical field is concerned, the 1H-indolopyridine structure is very important in drug development, and many bioactive molecules contain this structure. If the compound is connected to (4-cyanobenzyl) carboxyl groups, it can exhibit unique pharmacological activities, such as high affinity and selectivity for specific disease-related targets, it is expected to become a new drug lead compound. At present, many pharmaceutical companies and scientific research institutions are focusing on such compounds with innovative structures in search of novel therapeutic drugs. If the research and development goes well, it can successfully enter clinical trials and be approved for marketing, and its market size will be considerable, because the pharmaceutical market has a huge demand for high-efficiency and low-toxicity innovative drugs.
    In the field of materials science, this compound may exhibit special photoelectric properties due to its specific structure. If it can be applied in materials such as organic Light Emitting Diodes (OLEDs) and organic solar cells, giving materials better properties, such as higher luminous efficiency, longer service life, and stronger photoelectric conversion efficiency, it will surely win the attention of the materials market. With the vigorous development of electronic products and new energy industries, the demand for high-performance materials continues to rise. If this compound can meet the industry demand, its market share will gradually expand.
    However, its market expansion also faces challenges. The complexity of the synthesis process or affects the production cost. If it is difficult to achieve efficient and low-cost synthesis, it will limit its large-scale production and marketing activities. Furthermore, biosafety and environmental friendliness assessments are also indispensable. Failure to meet relevant standards in these aspects will also adversely affect its market prospects. Overall, the market of 1- [ (4-cyanobenzyl) carboxyl] -1H-indolopyridine has a bright future, but many obstacles need to be overcome to fully realize its market value.