1 4 Methoxy 2 Nitrophenyl 1h Imidazole
quinoline thiophene imidazole thiazole

1-(4-Methoxy-2-nitrophenyl)-1H-imidazole

    Specifications

    HS Code

    227596

    Chemical Formula C10H9N3O4
    Molar Mass 235.197 g/mol

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    General Information
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    Frequently Asked Questions

    As a leading 1-(4-Methoxy-2-nitrophenyl)-1H-imidazole supplier, we deliver high-quality products across diverse grades to meet evolving needs, empowering global customers with safe, efficient, and compliant chemical solutions.

    What are the chemical properties of 1- (4-methoxy-2-nitrophenyl) -1H-imidazole?
    1-% (4-methoxy-2-acetylbenzyl) -1H-pyrazole, the chemical properties of this compound are quite complex. In its structure, the presence of methoxy, acetyl and benzyl groups endows it with unique physical and chemical properties.
    Methoxy has a electron supply effect, which can affect the electron cloud density distribution of molecules, and then affect their chemical reactivity. In electrophilic substitution reactions, methoxy groups can increase the electron cloud density of the ortho and para-sites of the phenyl ring, making the electrophilic reagents more inclined to attack this position. Therefore, under certain conditions, this compound may undergo electrophilic substitution reactions in the ortho and para-sites of the phenyl ring.
    The carbonyl group of the acetyl group has a certain polarity, which can participate in a variety of reactions, such as nucleophilic addition reactions. Carbonyl carbons are partially positively charged and vulnerable to attack by nucleophilic reagents. If they encounter suitable nucleophilic reagents, such as alcohols, amines, etc., addition reactions may occur to generate corresponding acetals, amides and other derivatives.
    The pyrazole ring also has unique chemical activity. The nitrogen atom in the pyrazole ring has a lone pair of electrons, making it alkaline and can react with acids to form salts. At the same time, pyrazole rings can participate in various cyclization reactions, rearrangement reactions, etc., and are widely used in the field of organic synthesis.
    In addition, the spatial structure of the whole molecule of the compound will also affect its chemical properties. The steric hindrance of different substituents may affect the interaction between molecules, as well as the selectivity and rate of chemical reactions. In some reactions, the areas with large steric hindrance are difficult for the reagents to access, thus affecting the process of the reaction.
    In summary, the chemical properties of 1-% (4-methoxy-2-acetylbenzyl) -1H-pyrazole are synergistic by the structure of its various parts, showing rich reactivity and potential application value in organic synthesis and related fields.
    What are the main uses of 1- (4-methoxy-2-nitrophenyl) -1H-imidazole?
    1- (4-methoxy-2-acetylbenzyl) -1H-pyrazole, which has a wide range of uses. In the field of medicine, it can be used as a key intermediate to create a variety of drugs with specific curative effects. For example, some anti-inflammatory drugs, by chemically modifying and modifying 1- (4-methoxy-2-acetylbenzyl) -1H-pyrazole, the activity and selectivity of drug molecules can be precisely adjusted, so that it can act more effectively on inflammation-related targets, thereby achieving good anti-inflammatory effect. In the field of pesticides, this compound also has important applications. It can be used as a lead compound to develop pesticide products with high insecticidal and bactericidal properties. By optimizing its structure, it can enhance the toxic ability of pesticides to specific pests or bacteria, and help to improve the environmental adaptability and safety of pesticides, and reduce the adverse effects on non-target organisms. In addition, in the field of materials science, 1- (4-methoxy-2-acetylbenzyl) -1H-pyrazole also shows potential value. It can participate in the synthesis of some functional materials, endowing materials with unique physical and chemical properties, such as changing the optical and electrical properties of materials, providing new ideas and approaches for the development of new materials.
    What is the synthesis method of 1- (4-methoxy-2-nitrophenyl) -1H-imidazole?
    To prepare 1- (4-methoxy-2-pyridylphenyl) -1H-pyrazole, the following ancient methods can be used.
    First take appropriate raw materials, with 4-methoxy-2-pyridylphenyl related compounds and 1H-pyrazole precursor as the base. In the clean vessel, put an appropriate amount of organic solvent, such as dichloromethane, N, N-dimethylformamide, etc., depending on the reaction needs.
    Next, add suitable catalysts, such as some metal salt catalysts or organic base catalysts. If metal salts, zinc chloride, ferric chloride, etc. may be effective; organic bases such as triethylamine, pyridine, etc.
    Heat up to a suitable temperature, or at room temperature, or need to be heated to tens of degrees Celsius, depending on the reactivity. In the meantime, continue to stir to fully blend the reactants to promote the progress of the reaction.
    When reacting, pay close attention to the reaction process, which can be monitored by thin-layer chromatography and other means. When the reaction is complete, the product is treated by conventional separation and purification techniques. First, by extraction, the product is extracted from the reaction system with a suitable extractant, such as ethyl acetate, ether, etc. < Br >
    Then column chromatographic separation, select the appropriate silica gel, eluted with a specific ratio of eluent, to obtain a pure 1- (4-methoxy-2-pyridylphenyl) -1H-pyrazole product. During operation, it is necessary to strictly follow the procedures, pay attention to safety, and prevent the harm of organic solvents. In this way, the target product can be obtained.
    What is the market prospect of 1- (4-methoxy-2-nitrophenyl) -1H-imidazole?
    1- (4-methoxy-2-carbonylbenzyl) -1H-pyrazole is as follows:
    At present, the field of pharmaceutical research and development is quite concerned about this substance. It is a key intermediate in the process of organic synthesis. The combination of methoxy and carbonylbenzyl groups endows this substance with unique chemical properties and reactivity, and can play many subtle roles in the construction of complex organic molecular structures.
    Looking at it in the field of pharmaceutical chemistry, it was found that it exhibited a certain affinity for specific biological targets through experimental investigation. This property makes researchers hope to develop new specific drugs by modifying and optimizing their structures. Or for some difficult diseases, such as some chronic inflammatory diseases, specific tumor types, etc., it is expected to provide new treatment methods with drugs developed based on this substance.
    In the chemical industry, as an important raw material, it can participate in the preparation of a series of fine chemicals. The products involved cover material additives, functional additives, etc. The material additives synthesized by this substance can effectively improve the stability, durability and other properties of the material, and have potential application value in the production of plastics, rubber and other materials.
    However, the marketing activities of this substance also face challenges. Its synthesis process may be complex and costly, limiting large-scale production and wide application. And in terms of safety assessment, although some research results have been achieved, more in-depth and comprehensive toxicology and environmental impact studies are still needed to ensure that it has no potential harm to human body and the environment in industrial production and practical application.
    In summary, although 1- (4-methoxy-2-carbonylbenzyl) -1H-pyrazole has broad market prospects, it also needs to cooperate with scientific research and industry to overcome problems such as synthesis and safety in order to fully tap its commercial value and shine in the fields of medicine and chemical industry.
    What are the precautions for 1- (4-methoxy-2-nitrophenyl) -1H-imidazole during storage and transportation?
    1-% (4-methoxy-2-propylphenyl) -1H-pyrazole in the storage and transportation process, need to pay attention to many matters.
    First, the chemical structure of this material is special, and the temperature and humidity requirements of the storage environment are strict. The temperature should be constant in a specific range. If the temperature is too high, the molecular activity will be enhanced, or the chemical reaction will cause the material to deteriorate; if the humidity is too large, the water vapor may interact with the substance, which will affect its purity and stability. Therefore, it should be stored in a dry, cool and well-ventilated place, away from heat sources and water sources.
    Second, the packaging must be solid and reliable during transportation. It is necessary to choose packaging materials that can withstand a certain external force impact to prevent the package from being damaged due to bumps and collisions during transportation and cause the material to leak. At the same time, the packaging should have good sealing to avoid contact with outside air and moisture.
    Third, 1-% (4-methoxy-2-propylphenyl) -1H-pyrazole or with certain chemical hazards, transportation must strictly follow the relevant dangerous chemicals transportation regulations. Transport personnel should be professionally trained and familiar with the characteristics of the substance and emergency treatment methods. Transport vehicles should also be equipped with corresponding emergency equipment and protective equipment to prevent accidents.
    Fourth, storage and transportation sites should be clearly marked. Warning signs should be eye-catching, inform personnel of the danger of this substance and precautions, and remind irrelevant personnel not to approach. And the storage area should be stored in separate areas with other chemicals to avoid mutual reaction.
    In summary, 1-% (4-methoxy-2-propylphenyl) -1H-pyrazole cannot be ignored during storage and transportation, from environmental control to packaging requirements, from regulatory compliance to labeling warnings, to ensure the safe storage and transportation of this substance.