1-[4-(4-Chlorophenyl)-2-hydroxyl-butyl]imidazole

1-%5B4-%284-%E6%B0%AF%E8%8B%AF%E5%9F%BA%29-2-%E7%BE%9F%BA%E4%B8%80%E5%9F%BA%5D this structure is complex, it needs to be disassembled and analyzed step by step.
First look at 4- (4-hydroxyphenyl), 4-4 in parentheses is 0, so the remaining hydroxyphenyl group. At this time, the formula becomes 1- [4-hydroxyphenyl-2-furanyl-methyl].
From a chemical structure point of view, 1 often represents a specific position of a main chain or parent nucleus. In this structure, subsequent groups are connected to this position. "4-hydroxyphenyl", the phenyl group is a six-membered aromatic ring structure, and is connected to the hydroxyl group (-OH) at its position 4. " 2-Furanyl-methyl ", furan is a five-membered heterocyclic ring containing an oxygen atom, and the No. 2 position is connected to methyl (-CH 🥰). Overall, the structure is connected to a complex substituent composed of phenyl, hydroxyl, furanyl and methyl at a specific position 1. The combination and spatial arrangement of different groups in this structure will give it unique chemical properties, such as hydrophilicity of hydroxyl groups, aromaticity of phenyl groups and furan groups, etc., which affect the chemical reaction, physical properties and biological activities of the substance.

The main use of 1-% [4- (4-cyanobenzyl) -2-furyl-1-yl] pyridine is in the field of organic synthesis. This compound has a special chemical structure and shows important value in many aspects such as medicinal chemistry and materials science.
In medicinal chemistry, it can be used as a key intermediate to assist in the synthesis of compounds with specific biological activities. Due to its unique structure, it may be combined with specific targets in organisms. After reasonable chemical modification and modification, it is expected to develop new drugs, such as anti-cancer drugs, antiviral drugs, etc. For example, by adjusting its substituents, it can enhance the affinity with the surface receptors of cancer cells, thereby effectively inhibiting the growth and spread of cancer cells.
In the field of materials science, 1-% [4- (4-cyanobenzyl) -2-furyl-1-yl] pyridine may participate in the preparation of functional materials. With its special electronic structure and spatial configuration, it may endow materials with unique optical and electrical properties. For example, introducing it into polymer materials may improve the conductivity and fluorescence properties of materials, thereby preparing high-performance materials suitable for organic Light Emitting Diodes (OLEDs), solar cells and other fields. In conclusion, 1-% [4- (4-cyanobenzyl) -2-furyl-1-yl] pyridine has a wide range of important uses in the fields of medicine and materials related to organic synthesis due to its unique chemical structure, providing an important material basis and research direction for the research and development of related fields.

1-%5B4-%284-%E6%B0%AF%E8%8B%AF%E5%9F%BA%29-2-%E7%BE%9F%BA%E4%B8%80%E5%9F%BA%5D this formula, we first analyze each part. "-%E6%B0%AF%E8%8B%AF%E5%9F%BA" has strong chemical activity and often participates in a variety of organic reactions, which can significantly change the properties of compounds, such as affecting the polarity and stability of molecules. "-%E7%BE%9F%BA%E4%B8%80%E5%9F%BA" is very important in the field of biochemistry and organic synthesis. Its structure endows compounds with specific hydrogen bonding ability and has a key impact on the structure and function of biological macromolecules such as proteins and nucleic acids.
First calculate the parentheses: 4- (4-cyano) = cyano group, the formula changes to 1- [cyano-2-urea group], and further calculate 1-cyano + 2 + urea group = 3-cyano + urea group.
From the perspective of physical properties, compounds containing cyanide groups often have high boiling points due to the strong polarity of cyano groups, and some cyano compounds are toxic. The compounds where the urea group is located may have certain solubility in water due to the formation of hydrogen bonds by urea groups, and may affect the physical properties such as the melting point of the compounds. When the two coexist in the possible compounds represented by this formula, their physical properties will be determined by the interaction between the cyanyl group and the urea group and the overall molecular structure. The strong polarity of the cyanyl group interacts with the hydrogen bonding of the urea group, or makes the compound exhibit unique properties in terms of solubility and melting boiling point. For example, in polar solvents, the solubility may be different from that of compounds containing only a single group due to the action of the cyanyl group and the urea group on the solvent molecule. In terms of melting boiling point, the possible interaction between the cyanyl group and the urea group may enhance or weaken the intermolecular force, thereby changing the melting boiling point.

To prepare 1 - [4 - (4 - cyanobenzyl) - 2 - furanyl - acetyl] piperidine synthesis method, which has different ways, is described in detail as follows:
One, can be started by nucleophilic substitution reaction. First, take the appropriate halogenated hydrocarbon, so that it meets the nucleophilic reagent containing the cyanide group, and the two intersect to produce the structure of 4 - cyanobenzyl. Subsequently, based on this product, with the reactant containing the 2 - furanyl - acetyl moiety, under the catalysis of a suitable base agent, nucleophilic substitution is carried out, so that the two are connected to obtain the key intermediate. Finally, the intermediate is reacted with piperidine, and through a series of changes such as condensation, it becomes the target product. In this way, the choice of halogenated hydrocarbons, the nature and dosage of alkalis are all important factors that affect the success or failure.
Second, the heterocyclic ring can be started by constructing a heterocyclic ring. First, the heterocyclic ring structure containing 2-furan group is prepared, and the acetyl group is introduced at a specific position. At the same time, the fragment containing 4-cyanobenzyl is prepared. Then the two are coupled under suitable reaction conditions, such as with the help of metal catalysts, and the two are spliced together. Subsequently, the piperidine part is connected, and after modification and adjustment, 1 - [4 - (4 - cyanobenzyl) - 2 - furyl - acetyl] piperidine is finally obtained. Among them, the type of metal catalyst, reaction temperature and time have a great influence on the reaction process and product purity.
Third, the method of gradual condensation can be adopted. First, the simple structural units containing cyanobenzyl, furyl and acetyl groups are connected one by one in a condensation reaction, and the carbon chain is gradually increased to build a complex structure. Each step of condensation requires fine regulation of the reaction conditions, such as pH, reaction solvent, etc., to ensure that the reaction proceeds in the desired direction. After the key structure is constructed, it is finally condensed with piperidine to complete the synthesis of the target molecule. Although there are many steps in this way, each step has strong controllability, which is conducive to the purification and separation of the product.

1-% [4- (4-deuterobenzyl) -2-naphthyl-1-yl] piperidine is mainly used in the medical field for the treatment and research of neurological diseases. In the development of psychiatric drugs, it is of great significance for the development of some neurotransmitter-modulating drugs. For example, in the exploration of new drugs for depression and anxiety disorders, the compound can act on specific neurotransmitter receptors due to its unique chemical structure. By modulating the balance of neurotransmitters, it is expected to relieve depression and anxiety symptoms in patients.
It also shows potential value in the study of neurological diseases such as Parkinson's disease. Parkinson's disease is mainly caused by the degeneration and death of dopaminergic nerve cells in the brain, resulting in a decrease in dopamine secretion. This compound may play a certain protective role on dopaminergic nerve cells by affecting related neural signaling pathways, or regulate the metabolism and release of dopamine, providing new ideas and methods for the treatment of Parkinson's disease.
In the field of medicinal chemistry, 1-% [4- (4-deuterobenzyl) -2-naphthyl-1-yl] piperidine is often used as a key intermediate. Medicinal chemists use its structural characteristics to synthesize a series of novel compounds with different activities through chemical modification and derivatization reactions. With the help of structural modification, the pharmacokinetic properties of compounds can be optimized, such as improving bioavailability and prolonging the time of action of drugs in the body, thus enabling the development of more efficient and safe drugs.