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What are the main uses of 1- (2-phenethyl) -1H-imidazole?
1- (2-benzyl) -1H-pyrazole is widely used. In the field of medicine, it is often used as a key intermediate to synthesize many drugs with specific biological activities. For example, some drugs with anti-inflammatory, antibacterial and anti-tumor effects, in the synthesis process, 1- (2-benzyl) -1H-pyrazole can use its unique chemical structure to skillfully combine with other compounds through a series of chemical reactions to construct drug molecules with precise pharmacological effects, thus contributing to the treatment of diseases.
In the field of pesticides, it also plays an important role. The creation of some new pesticides will include them. By virtue of their structural characteristics, pesticides are endowed with excellent characteristics such as high efficiency, low toxicity, and environmental friendliness. They can not only effectively kill pests, inhibit the growth of pathogens, and ensure the thriving growth of crops, but also reduce the negative impact on the ecological environment. In line with the current needs of green agriculture.
In the field of materials science, 1- (2-benzyl) -1H-pyrazole also shows unique value. It can be used to prepare some functional materials, such as specific polymer materials, by introducing them into the polymer structure, the properties of the material can be improved, such as enhancing the stability and flexibility of the material or endowing it with special optical and electrical properties, etc., thereby expanding the application scenarios of materials in different fields, such as electronic devices, optical instruments, etc.
What are the physical properties of 1- (2-phenethyl) -1H-imidazole?
1 - (2 -furyl) -1H -pyrazole This substance has unique and different properties. It is an organic compound, in the shape or crystalline state, with a color or near-transparent, slightly specific odor.
In terms of its melting point, the melting point often varies according to its purity and changes in the surrounding environment, and is generally within a certain range; the boiling point is also due to the interaction of various atoms in the structure, and it can be boiled and converted to a gaseous state at a specific temperature.
In terms of solubility, because there are polar groups distributed inside the molecule, it can show a certain solubility in polar solvents such as alcohols. However, in non-polar solvents such as alkanes, the solubility is quite limited. < Br >
In terms of stability, it can maintain a relatively stable state under normal circumstances. When encountering strong oxidizing agents, strong acids and bases, its structure may be difficult to maintain intact, easily triggering chemical reactions, causing structural reorganization or bond fracture.
Spectral properties also have characteristics. In the infrared spectrum, the vibration of atoms on the furan group and pyrazole ring can show characteristic absorption peaks at specific wavenumbers, which can be used for structure identification. In the nuclear magnetic resonance spectrum, hydrogen atoms at different positions exhibit unique chemical shifts due to their different chemical environments, providing key clues for analyzing their fine structures. In the field of organic synthesis, 1- (2-furyl) -1H-pyrazole is often used as a key intermediate. With its active chemical properties, it participates in many reactions and helps to create a variety of organic compounds.
What are the chemical properties of 1- (2-phenethyl) -1H-imidazole?
1- (2-Benzyl) -1H-pyrazole, this is an organic compound. It has unique chemical properties and is very important in the field of organic synthesis.
From the structural point of view, the compound contains a pyrazole ring, which is a five-membered heterocycle composed of two nitrogen atoms and three carbon atoms, giving it many special chemical activities. Substitution of 2-benzyl groups introduces benzyl groups into the molecule, which affect the electron cloud distribution and spatial structure of the molecule, and then change its chemical properties.
One of its chemical properties is alkaline. The nitrogen atom on the pyrazole ring has a solitary pair of electrons, accepts protons, and exhibits certain alkalinity. This alkalinity enables it to react with acids to form corresponding salts. For example, in the case of strong acids, nitrogen atoms can bind protons to form positively charged ions.
Nucleophilicity is also an important property. The solitary pair electrons of the nitrogen atom in the pyrazole ring make it nucleophilic and can undergo nucleophilic substitution reactions with electrophilic reagents. Under suitable conditions, it can react with electrophilic reagents such as halogenated hydrocarbons to introduce new groups on the pyrazole ring to achieve molecular structure modification and functional expansion.
In addition, the compound has certain stability and electron delocalization properties due to the conjugated system. The conjugated system can make the distribution of electron clouds in the molecule more uniform and enhance its stability. This property affects the spectral properties of compounds, and there are specific absorption peaks in the ultraviolet-visible spectrum, which can be used for structure identification and analysis.
1- (2-benzyl) -1H-pyrazoline has unique chemical properties and is widely used in pharmaceutical chemistry, materials science and other fields. It is an important intermediate for organic synthesis and related research.
What are the synthesis methods of 1- (2-phenethyl) -1H-imidazole?
The synthesis method of 1- (2-benzyl) -1H-indole has been recorded in many books, and the main one is selected here.
First, o-nitrotoluene and styrene are used as starting materials. First, under specific conditions, o-nitrotoluene is converted into an intermediate containing a specific functional group through an ingenious reaction. This intermediate meets styrene again, and under the help of suitable temperature, pressure and catalyst, the two interact and go through a series of complex chemical changes, among which the chemical bonds are very delicate to break and recombine, and finally gradually build the basic structure of 1- (2-benzyl) -1H-indole, and then purify and purify to obtain the target product.
Second, aniline and 2- (bromomethyl) benzaldehyde are used as raw materials. The amino group of aniline reacts with the aldehyde group of 2- (bromomethyl) benzaldehyde and bromomethyl in a carefully prepared reaction system, such as a suitable solvent and a precisely controlled pH environment. First, the aldehyde group is condensed with the amino group to form a nitrogen-containing cyclic intermediate, and then the bromomethyl group participates in the reaction, initiates a series of steps such as cyclization, and gradually shapes the unique structure of 1- (2-benzyl) -1H-indole. After careful separation and purification operations, impurities are removed and pure products are harvested.
Third, indole and benzyl halide are used as starting materials. Indole is placed in a specific reaction vessel, an appropriate amount of base is added to adjust the chemical environment of the system, and then benzyl halide is slowly added. The presence of a base prompts the activation of the nitrogen atom of the indole, enhances its nucleophilicity, and enables it to undergo a nucleophilic substitution reaction with the benzyl moiety of the benzyl halide, thereby introducing benzyl at the 1 position of the indole to generate 1- (2-benzyl) -1H-indole. After the reaction is completed, the desired product can be obtained by regular separation and purification methods.
What is the price range of 1- (2-phenethyl) -1H-imidazole in the market?
The price range of 1- (2-benzyl) -1H-indole in the market is difficult to determine. The price of the cover often changes for many reasons.
Looking at the "Tiangong Kaiwu", the price of all things in the world is related to materials, labor, supply and demand. This 1- (2-benzyl) -1H-indole is no exception. If the picking of materials is difficult, or the preparation is complicated and requires a lot of labor, the price must be high.
And the supply and demand of the market has a huge impact on its price. If there are many people who want it, but there are few people who supply it, the price will increase; on the contrary, if the supply exceeds the demand, the price will be depressed.
Furthermore, the regional differences in production and sales also affect the price. In prosperous and common cities, the price of goods converges, or due to competition, the price may be leveled; while in remote places, the transshipment is difficult, and the price may increase.
If you want to know the range of its price, you must actually consider the merchants and brokers of various cities, and carefully observe the current market situation, so that you can obtain a more accurate price range, rather than a word can be hidden.