1-[(2-Fluorophenyl)(4-fluorophenyl)phenylmethyl]-1H-imidazole

1 - [ (2-hydroxybenzyl) (4-hydroxybenzyl) benzylethyl] -1H-imidazole has important uses in medicine, chemical industry and other fields.
In medicine, it can be used as a key intermediate in drug synthesis. The structure of Gainimidazole gives it unique chemical and biological activities, and can interact with many biological macromolecules in the body. Through specific chemical reactions, access to (2-hydroxybenzyl) (4-hydroxybenzyl) benzylethyl and other groups, drugs with specific pharmacological effects, such as antibacterial and anti-inflammatory drugs, can be developed. Due to the introduction of these groups, the lipophilicity and hydrophilicity of the drug may be changed, which in turn affects the transmembrane transport and in vivo distribution of the drug, improves the affinity and selectivity of the drug to specific targets, enhances the curative effect, and reduces the toxic and side effects.
In the field of chemical industry, it can be used as a raw material for the synthesis of new materials. In the synthesis of polymer materials, the activity check point of this compound can be used to participate in the polymerization reaction to construct a polymer with special properties. For example, giving the material better stability, thermal properties, mechanical properties, etc. In addition, in the preparation of fine chemical products, such as coatings and adhesives, the performance of the product can also be optimized by virtue of its special structure, such as enhancing the adhesion and durability of the coating, and improving the bonding strength of the adhesive.
In summary, 1- [ (2-hydroxybenzyl) (4-hydroxybenzyl) benzylethyl] -1H-imidazole plays an important role in the field of medicine and chemical industry due to its unique chemical structure, providing an important material basis for the development of related industries.

1 - [ (2 -furyl) (4 -furyl) furanyl ethyl] -1H -pyrazole is an organic compound, to clarify its physical properties, and in the classical Chinese style of "Tiangong Kaiwu", detailed as follows:
The morphology of this compound is either crystalline under normal circumstances, like ice crystals, radiant and regular shape, under the reflection of light, there is sparkling brilliance; or amorphous, like a paste of condensation, uniform and amorphous state.
When its color is pure, it may be colorless and transparent, like clear water, transparent and flawless; however, if it contains miscellaneous, it may appear a yellowish luster, such as the first blooming of autumn chrysanthemum, elegant without losing its charm.
When it comes to smell, this compound is in an ordinary environment, or exudes a quiet fragrance. If Zhilan is born in a valley, it is elegant and pleasant; or it is in an odorless state, like an invisible breath, and it is difficult to find its trace.
As for the melting point, this compound is in a specific range due to its unique structure. When heated, it initially appears as solid ice, gradually softens, and melts into a liquid when it reaches the melting point. This state of transformation is like winter snow meeting spring, quietly melting water. The boiling point of
is also one of its important physical properties. When the temperature gradually rises to the boiling point, the compound jumps from liquid to gaseous state and turns into an invisible fog. This process is ethereal and fantastical if the cloud and mist evaporate.
In terms of solubility, in polar solvents, such as alcohols, or soluble ones, it is like salt melting in water, which is invisible and invisible; in non-polar solvents, such as hydrocarbons, or insoluble ones, such as oil floating in water.
The density is different from that of water. If it is larger than water, it sinks to the bottom of the water, such as a stone falling into an abyss; if it is smaller than water, it floats on the water surface, such as a flat floating in a lake.
The above are all the physical properties of this 1- [ (2-furyl) (4-furyl) furanyl ethyl] -1H-pyrazole, although not exhaustive, it can also be seen.

This is a compound of 1- [ (2-furanyl) (4-furanyl) furanyl ethyl] -1H-pyrazole. Its chemical properties are as follows:
- ** Physical properties **: This compound is mostly crystalline solid and stable at room temperature and pressure. Due to the presence of a variety of aromatic ring structures and strong intermolecular forces, the melting point is relatively high, and the solubility in organic solvents varies depending on the properties of the solvent. Common organic solvents such as ethanol and dichloromethane may have certain solubility. Because they contain both polar group pyrazole ring and non-polar furyl and ethyl group, there is a certain balance between polar and non-polar solvents. < Br > - ** Chemical Stability **: The pyrazole ring is aromatic, the electron cloud is uniformly distributed, and the structure is stable. However, the nitrogen atom on the pyrazole ring has a lone pair of electrons, which is alkaline to a certain extent, and can react with acids to form salt compounds. Although the furan group is also aromatic, the oxygen atom is highly electronegative, causing uneven distribution of the electron cloud density of the furan ring, and the electron cloud density of the α-position is high, which is prone to electrophilic substitution reactions, such as halogenation, nitrification, sulfonation, etc. And the furan ring is sensitive to acids, and it is easy to open the ring or rearrange in case of strong acids. < Br > - ** Reactivity **: The ethyl part of the compound can be substituted, such as nucleophilic substitution with halogenated hydrocarbons under basic conditions, and different substituents are introduced to modify the properties of the compound. The nitrogen atom of the pyrazole ring can be used as a nucleophilic check point to acylate with acyl halides, acid anhydrides, etc., to generate derivatives containing amide bonds. This reaction can be used in organic synthesis to construct complex structures and introduce functional groups to expand the biological activity and application range of compounds.

To prepare 1 - [% 5B (2-furanyl) (4-furanyl) furanoethyl% 5D-1H-pyrrole, there are three methods.
One is the method of condensation cyclization. First, take appropriate furan derivatives, such as 2-furanaldehyde and 4-furanaldehyde, and make them with compounds with active hydrogen, under the condition of basic or acidic catalysis. If an alkaline catalyst is used, the two can be condensed to form alkenaldehyde intermediates containing furanyl groups. Then, the intermediate and the amino-containing compound are further cyclized in a suitable temperature and solvent to obtain 1 - [% 5B (2-furyl) (4-furyl) furanoethyl% 5D-1H-pyrrole. In this process, the reaction conditions, such as temperature, pH, etc., need to be carefully regulated to increase the yield and purity of the product.
The second is the method of catalysis by transition metals. Using transition metals such as palladium and nickel as catalysts, suitable ligands are selected to couple the halogenated compounds containing furan groups with alkenyl or alkynyl groups in the presence of bases. Forming an intermediate with a specific structure of the furyl conjugate system. After that, through the cyclization reaction in the molecule, under suitable conditions, the ring is closed to form the target product. This method requires strict requirements on catalysts and reaction conditions, and requires precise control to obtain satisfactory results.
The third is the method of biosynthesis. Using the catalytic properties of microorganisms or enzymes, with suitable biological substrates, through enzymatic reactions in vivo, the structure of the target molecule is gradually constructed. For example, microbial strains with specific catalytic activities are screened, and simple compounds containing furan groups are used as the starting substrates. Through complex metabolic pathways and enzyme-catalyzed reactions in vivo, 1- [% 5B (2-furan) (4-furan) furan ethyl% 5D-1H-pyrrole is generated. This method is green and environmentally friendly, but the biological system is complex, and it is necessary to further study the biological metabolic mechanism and optimize the culture conditions to improve the yield of products.

What is the price of 1- [ (2-furyl) (4-furyl) furanyl ethyl] -1H-pyrazole in the market today? This is a rather professional chemical, and its price varies depending on quality, purity, suppliers and market supply and demand.
If it is of ordinary experimental purity, the supplier's supply is also moderate, and the price may be a few to ten yuan per gram. However, if it is required to be of high purity, up to analytical purity or even higher, for high-end scientific research purposes, the price will rise sharply, to more than 100 yuan per gram.
Furthermore, if the market demand for this product is strong and the supply is limited, the price will also rise according to the reason of supply and demand. On the contrary, if the supply exceeds the demand, the price may be lowered. To determine the actual price, please consult the chemical reagent supplier for details, and the latest quotation shall prevail.