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What is the chemical structure of 1- {2- [ (4-chlorobenzyl) sulfanyl] -2- (2,4-dichlorophenyl) ethyl} -1H-imidazole nitrate (1:1)
1 - {2 - [ (4 -chlorobenzyl) thio] -2 - (2,4 -dichlorophenyl) ethyl} -1H -imidazole nitrate (1:1), according to its name, it can be seen that this is an organic compound.
Its main body is 1H-imidazole, which is connected to a complex side chain at position 1. In the side chain, the 2-position carbon atom is connected to [ (4-chlorobenzyl) thio] and (2,4-dichlorophenyl) ethyl. [ ( 4-Chlorobenzyl) thio], the benzyl ring of benzyl is substituted with a chlorine atom at the 4th position, and is connected to the main chain by a sulfur atom. (2,4-dichlorophenyl) ethyl, that is, ethyl is connected to the main chain at one end, and the other end is connected with a 2,4-dichloro-substituted benzene ring.
Furthermore, this compound is nitrate, and the ratio to the main part is 1:1. Nitrate is formed by combining the compound with nitrate ions in a specific ratio. In this way, the chemical structure of 1 - {2 - [ (4-chlorobenzyl) thio] -2 - (2,4-dichlorophenyl) ethyl} -1H -imidazolium nitrate (1:1) is largely clear. Its unique structure may endow the compound with specific chemical and physical properties, which may have unique uses in organic synthesis, medicinal chemistry and other fields.
What are the physical properties of 1- {2- [ (4-chlorobenzyl) sulfanyl] -2- (2,4-dichlorophenyl) ethyl} -1H-imidazole nitrate (1:1)
1 - {2 - [ (4 -chlorobenzyl) thio] -2 - (2,4 -dichlorophenyl) ethyl} -1H -imidazolium nitrate (1:1) is an organic compound. Its physical properties are unique, and I will tell you one by one.
Looking at its appearance, under room temperature and pressure, it is mostly white to white-like crystalline powder. This state is delicate, like the first fall of fresh snow in winter, with uniform texture and tiny particles, which seem to flicker under light.
Talking about the melting point, it is about [X] ° C. When the temperature gradually rises to this point, this substance will be like ice in the warm sun, slowly melting from solid to liquid, this process occurs quietly, just like the melting of ice and snow in spring, gentle and orderly.
Its solubility is also an important property. In organic solvents, such as dichloromethane and chloroform, this substance can exhibit good solubility, just like fish entering water, easily fusing to form a uniform and stable solution; however, in water, the solubility is quite limited, just like oil droplets entering water, difficult to dissolve, only a small amount can be dispersed, just like water droplets on lotus leaves, forming a self-contained whole.
The density of this compound is about [X] g/cm ³. When placed in a specific container, the specific ratio between its mass and volume can be sensed. It seems to follow the established laws of nature, which is calm and orderly.
In addition, its stability is also worth mentioning. Under normal conditions, this compound is relatively stable and can be stored for a long time without significant changes, just like the toughness of a rock; however, in case of special conditions such as high temperature, strong oxidants or specific catalysts, its chemical structure may change, triggering a series of chemical reactions, just like a calm lake throwing boulders and rippling layer by layer.
What is the use of 1- {2- [ (4-chlorobenzyl) sulfanyl] -2- (2,4-dichlorophenyl) ethyl} -1H-imidazole nitrate (1:1)
1-% {2- [ (4-chlorobenzyl) thio] 2- (2,4-dichlorophenyl) ethyl} -1H-imidazole nitrate (1:1), this is a chemical substance that is useful in many fields.
In the field of medicine, its role is quite obvious. It can be used as an antibacterial drug to interfere with the normal physiological metabolism of bacteria by combining specific chemical structures with key internal targets, such as hindering cell wall synthesis, inhibiting protein and nucleic acid synthesis, etc., thereby inhibiting bacterial growth and reproduction, providing strong support for the treatment of bacterial infectious diseases. Or as a potential antifungal agent, it can affect fungal cell membranes or specific metabolic pathways, destroy fungal cell integrity and function, and be used to fight fungal infections.
In the chemical industry, it may be used as a catalyst. Due to its unique chemical activity, it can reduce the activation energy of certain chemical reactions, speed up the reaction rate, and improve the efficiency of chemical production. Its own chemical properties and quality are basically unchanged before and after the reaction, and it can be recycled many times to reduce production costs. In the field of materials science, it may be able to participate in material modification. Through chemical reactions or physical interactions with material matrices, improve material properties, such as enhancing material stability and improving material corrosion resistance, etc., providing more possibilities for the development and production of new materials.
However, during the use of this substance, caution is required. Because of its specific chemical activity, or potential impact on the environment and human body. Be sure to follow strict operating procedures and safety standards when using, and take protective measures to ensure the safety of personnel and the environment from harm.
What is the synthesis method of 1- {2- [ (4-chlorobenzyl) sulfanyl] -2- (2,4-dichlorophenyl) ethyl} -1H-imidazole nitrate (1:1)
To prepare 1 - {2 - [ (4 - chlorobenzyl) thio] -2 - (2,4 - dichlorophenyl) ethyl} -1H - imidazole nitrate (1:1), the method is as follows:
First, all raw materials need to be prepared, 4 - chlorobenzyl mercaptan, 2,4 - dichlorobenzene vinyl, etc. are indispensable.
First, 4 - chlorobenzyl mercaptan and alkali, such as sodium hydroxide, are fully reacted in a suitable solvent, or in ethanol or acetone, to generate the corresponding mercaptan salt. This process requires temperature control to stabilize the temperature within a certain range. Do not let it be too high or too low to cause the reaction to be biased.
Mix the prepared mercaptan with 2,4-dichlorobenzene at a time, add an appropriate amount of catalyst, such as palladium catalyst, in an inert gas atmosphere, such as nitrogen, heat and stir. During the reaction, the reaction process needs to be carefully observed, which can be monitored by thin-layer chromatography and other methods. When the reaction reaches the desired level, it will stop.
To obtain the reaction product, it will be separated and purified. First, by the method of extraction, select the appropriate extractant, and separate the product from the reaction system. After column chromatography or recrystallization, its impurities are removed to make the product pure. Then, mix the mentioned 1- {2- [ (4-chlorobenzyl) thio] -2 - (2,4-dichlorophenyl) ethyl} -1H-imidazole with nitric acid in a suitable solvent in a ratio of 1:1 and stir at room temperature to obtain 1- {2- [ (4-chlorobenzyl) thio] -2 - (2,4-dichlorophenyl) ethyl} -1H -imidazole nitrate (1:1). Finally, after drying and other post-treatment processes, a pure product can be obtained.
1- {2- [ (4-chlorobenzyl) sulfanyl] -2- (2,4-dichlorophenyl) ethyl} -1H-imidazole nitrate (1:1) What are the safety precautions
1-% {2- [ (4-chlorobenzyl) thio] 2- (2,4-dichlorophenyl) ethyl} -1H -imidazolium nitrate (1:1) is a special chemical. When using and contacting, many safety precautions must be kept in mind.
This chemical may be toxic and can cause varying degrees of damage to the human body. First, avoid inhaling its dust, smoke or vapor. If it enters the respiratory tract, or irritates the mucosa of the respiratory tract, it can cause coughing, asthma, long-term or severe exposure, and even damage lung function. When operating, it is recommended to use a well-ventilated place, or with the help of ventilation equipment, such as a fume hood, to reduce the concentration of chemicals in the air.
Second, prevent skin contact. The substance comes into contact with the skin, or causes irritation, allergic reactions, such as redness, swelling, itching, and rash. Wear appropriate protective equipment during operation, such as protective gloves, lab clothes, etc. If you contact it inadvertently, rinse with plenty of water quickly and seek medical attention if necessary.
Third, avoid eye contact. Once in the eyes, it will cause serious irritation and damage to the eyes, affecting vision. It is recommended to wear eye protective equipment such as goggles during operation. If you accidentally enter the eyes, rinse with plenty of water immediately and seek medical attention as soon as possible.
Fourth, this chemical is chemically active. When storing, it should be kept away from fire and heat sources, and avoid mixing with strong oxidants, strong acids, strong bases and other substances to prevent severe chemical reactions from occurring, causing serious accidents such as fires and explosions. The storage place should be kept dry, cool and ventilated.
Finally, when operating this chemical, relevant personnel should be professionally trained to be familiar with its properties, safety operating procedures and emergency treatment methods. Emergency rescue equipment and medicines should also be prepared on site to deal with emergencies.