1-{2-[(2-chlorothiophen-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole

1-% 7B2-% 5B% 282-chlorothiophene-3-yl% 29 methoxy% 5D-2 - (2,4-dichlorophenyl) ethyl% 7D-1H-imidazole The chemical structure of this compound can be explained as follows.
"1H-imidazole", this is a five-membered nitrogen-containing heterocyclic structure, which has two nitrogen atoms on the ring and begins to connect other groups at the hydrogen atom at position 1. < Br >
"1 - {2 - [ (2-chlorothiophene-3-yl) methoxy] -2 - (2,4-dichlorophenyl) ethyl}", indicating that a complex alkyl structure is connected at the 1 position of the imidazole ring. " 2 - [ (2 - chlorothiophene - 3 - yl) methoxy] - 2 - (2,4 - dichlorophenyl) ethyl ", where" 2 - (2,4 - dichlorophenyl) ethyl "means that a 2,4 - dichlorophenyl is connected at the 2 position of ethyl; and" 2 - [ (2 - chlorothiophene - 3 - yl) methoxy] ", that is, the 2 position of this ethyl is also connected to a methoxy group with 2 - chlorothiophene - 3 - group as a substituent.
In general, the core of the chemical structure of this compound is a 1H-imidazole ring, which is connected to an ethyl side chain containing 2-chlorothiophene-3-methoxy and 2,4-dichlorophenyl at its first position. In the field of organic chemistry, this structure may have specific applications and research values in pharmaceutical chemistry, materials science and other fields due to its various halogen atoms and heterocycles, or its unique chemical activities and physical properties.

1 - {2 - [ (2-chlorothiophene-3-yl) methoxy] -2 - (2,4-dichlorophenyl) ethyl} -1H -imidazole, this is an organic compound. It has a wide range of uses, in the field of medicine, or as a key drug synthesis intermediate. Taking the creation of antifungal drugs as an example, in the synthesis path of many azole antifungal drugs, compounds with this structure can be used as important starting materials or intermediates. Through a series of chemical reactions, they are constructed into drug molecules, giving the drug the ability to inhibit or kill fungi. Because the azole ring structure can interact with specific targets in fungal cells and interfere with the normal physiological metabolism of fungi.
In the field of pesticides, or for the synthesis of pesticides with high insecticidal and bactericidal activities. Because its structure can be modified and adjusted, it exhibits high selectivity and activity against specific pests or pathogens, providing assistance for the prevention and control of agricultural pests and diseases. In addition, in the field of chemical research, as an important block of organic synthesis, scientists can explore various novel organic reactions based on its unique chemical structure and reactivity, and synthesize organic compounds with more complex structures and more specific properties, providing a new material basis for materials science, drug development and many other fields.

To prepare 1 - {2 - [ (2 - chlorothiophene - 3 - yl) methoxy] -2 - (2,4 - dichlorophenyl) ethyl} -1H - imidazole, there are many ways to synthesize it.
One method is to take 2,4 - dichloroacetophenone first, and deal with it with an appropriate base, so that it reacts with (2 - chlorothiophene - 3 - yl) methyl halide nucleophilic substitution. The halide can be a bromide or a chloride. In a suitable solvent, such as N, N-dimethylformamide (DMF) or acetonitrile, the temperature is controlled and the reaction is delayed to obtain an intermediate product. The carbonyl group of the intermediate product is then reduced to an alcohol hydroxyl group with a suitable reducing agent, such as sodium borohydride or lithium aluminum hydride. Thereafter, the alcohol-containing compound is condensed with imidazole in the presence of a dehydrating agent, such as dicyclohexyl carbodiimide (DCC) and 4-dimethylaminopyridine (DMAP), to obtain the target product.
Another method is to first halogenate (2-chlorothiophene-3-yl) methanol to form the corresponding halogen. Then Heck reaction with 2,4-dichlorophenyl vinyl under the action of palladium catalyst and base agent to obtain an intermediate containing double bonds. Then make this intermediate and imidazole under the initiation of peroxide to perform free radical addition reaction, and the desired 1 - {2 - [ (2-chlorothiophene-3-yl) methoxy] -2 - (2,4-dichlorophenyl) ethyl} -1H -imidazole can also be obtained.
In addition, with 2,4-dichlorobenzoic acid as the starting material, the acid chloride is first prepared, esterified with (2-chlorothiophene-3-yl) methanol, and then the ester group is reduced to alcohol, and the subsequent reaction with imidazole is also feasible. Each method has its own advantages and disadvantages, and it is necessary to choose carefully depending on the availability of raw materials, reaction conditions, and high or low yield.

1-% 7B2-% 5B% 282-chlorothiophene-3-yl% 29 methoxy% 5D-2 - (2,4-dichlorophenyl) ethyl% 7D-1H-imidazole This substance has unique physical and chemical properties. Under normal conditions, it is a white-like to light yellow crystalline powder. It is fine and uniform in appearance, with a pure texture and little variegation and foreign matter.
The melting point is about 145-149 ° C. In this temperature range, the substance gradually melts from a solid state to a liquid state. This property is of critical value when identifying and purifying the substance.
Its solubility is also an important property. This substance is slightly soluble in water, just like a lone boat on the surface of a vast river. It is difficult to blend with water and can only be dispersed in a very small amount. However, in organic solvents, such as dichloromethane, ethanol, etc., it shows good solubility and can blend with organic solvents to form a uniform and stable solution.
In terms of chemical stability, under conventional environmental conditions, this substance is quite stable and is not prone to spontaneous chemical changes. However, if placed in a strong acid, strong alkali environment, or under extreme conditions of high temperature, high humidity and aerobic, some chemical bonds in the molecular structure are easily affected, and reactions such as hydrolysis and oxidation occur, resulting in changes in the chemical structure and properties of the substance.
Its spectral properties are also worth exploring. In infrared spectroscopy, the vibration of chemical bonds between specific atoms produces characteristic absorption peaks, which can be used to determine the functional groups contained in molecules. In nuclear magnetic resonance spectroscopy, hydrogen atoms or other magnetic nuclei in different chemical environments will show resonance signals at corresponding positions, which provides key information for analyzing molecular structures.
In summary, the physicochemical properties of 1-% 7B2-% 5B% 282-chlorothiophene-3-yl% 29methoxy% 5D-2 - (2,4-dichlorophenyl) ethyl% 7D-1H-imidazole lay a solid foundation for its research in synthesis, analysis, application and other fields.

1-% {2- [ (2-chlorothiophene-3-yl) methoxy] -2 - (2,4-dichlorophenyl) ethyl} -1H-imidazole, this compound has attracted much attention in the field of pharmaceutical research and development, and the market prospect is quite promising.
It shows unique advantages in the field of antifungal drugs. Due to the specific groups in its structure, it has high inhibitory activity against a variety of fungi. Many scientific research teams have focused on this to explore its mechanism of action against common pathogenic fungi such as Candida albicans and Aspergillus. Some of the previous research results have been remarkable, indicating that it is expected to become a new generation of antifungal drugs. If the research and development goes well, after it is put on the market, it will bring new treatment options for patients with fungal infections, fill the gap of related drugs, and the market share may be considerable.
In the field of pesticides, it has also emerged. Studies have shown that the compound has repellent or poisonous effects on some crop pests. Based on field trials, the control effect on common pests such as aphids and mites is significant. If it can be successfully developed into a pesticide product, it is in line with the current trend of green, environmentally friendly, efficient and low-toxicity pesticides. In the agricultural market, whether it is the cultivation of cash crops or food crops, there will be broad application space to meet the urgent needs of farmers for new pesticides, and the market potential is huge.
However, its market development also faces challenges. The complexity of the synthesis process leads to high production costs, limiting large-scale production and promotion. And new drugs or new pesticides need to go through a strict approval process, which is long and costly. Only when researchers and enterprises work together to break through the bottleneck of synthesis technology, reduce costs, and actively respond to the approval process can this compound shine in the market and create considerable economic value and social benefits.