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What is the chemical structure of 1- {2- [ (2,6-dichlorobenzyl) oxy] 2- (2,4-dichlorophenyl) ethyl} -1H-imidazole?
The chemical structure of 1 - {2 - [ (2,6 -dioxobenzyl) oxy] -2 - (2,4 -dioxobenzyl) ethyl} -1H -pyrazole is an interesting research object in the field of organic chemistry.
The structure of this compound can be analyzed from its naming. 1H-pyrazole is its core structure, pyrazole is a five-membered heterocyclic compound containing two adjacent nitrogen atoms. At the 1-position, a complex substituent is connected. From the outside to the inside, the outermost layer of the substituent is an ethyl fragment. The 2-position of this ethyl group is connected to (2,4-dioxobenzyl), and in the same position, it is also connected to 2 - [ (2,6-dioxobenzyl) oxy]. Wherein, the benzyl group is benzyl, and the dioxo generation is the introduction of two carbonyl groups (C = O) at specific positions in the corresponding benzene ring.
From this point of view, the chemical structure of 1 - {2- [ (2,6-dioxobenzyl) oxy] -2 - (2,4-dioxobenzyl) ethyl} -1H -pyrazole is centered on 1H-pyrazole, and different substituents are ordered and combined by a specific connection method to form a relatively complex organic molecular structure. This structure may endow the compound with unique physical, chemical and biological activities, and may have potential application value in many fields such as organic synthesis and drug development.
What are the main uses of 1- {2- [ (2,6-dichlorobenzyl) oxy] 2- (2,4-dichlorophenyl) ethyl} -1H-imidazole?
1 - {2 - [ (2,6 - dihydroxyphenyl) oxy] - 2 - (2,4 - dihydroxyphenyl) ethyl} -1H - indole This substance is widely used in medicine. It can be used as a pharmaceutical active ingredient and is beneficial in the treatment of neurological diseases. Such as Parkinson's disease, this disease is caused by damage to nerve cells in the brain resulting in insufficient dopamine secretion, and this substance may regulate neurotransmitters and improve symptoms.
Furthermore, it is also effective in the prevention and treatment of cardiovascular diseases. It may regulate blood lipids, so that lipid levels in the blood reach a balanced state and reduce the risk of atherosclerosis. It can also dilate blood vessels, let blood flow freely, and reduce the hidden dangers of hypertension.
In the field of anti-inflammatory, this substance also plays a role. It can inhibit the release of inflammatory mediators, reduce inflammatory reactions, and relieve pain and swelling in inflammatory diseases such as arthritis.
In the path of scientific research and exploration, this substance provides the cornerstone for many studies. Scholars use its characteristics to explore physiological and pathological mechanisms, and find new ideas for the development of new drugs, which is expected to open up more effective therapies and bring good news to patients.
What are the physical properties of 1- {2- [ (2,6-dichlorobenzyl) oxy] 2- (2,4-dichlorophenyl) ethyl} -1H-imidazole?
1 - {2- [ (2,6 -dihydroxyphenyl) oxy] -2 - (2,4 -dihydroxyphenyl) ethyl} -1H -indole This substance has the following physical properties:
In appearance, it is often presented in a solid state. Due to the arrangement and interaction of atoms in the molecular structure, the intermolecular force causes the substance to tend to aggregate into a solid state. The color is mostly white to light yellow powder, which is due to the absorption and reflection characteristics of visible light by molecules. The chromophore and conjugate system contained in its structure selectively absorbs light of specific wavelengths, and the reflected light is white to light yellow in visual perception.
In terms of solubility, due to the presence of multiple polar hydroxyl groups in the molecule, it has a certain solubility in polar solvents (such as methanol, ethanol, water). Hydroxyl groups can form hydrogen bonds with polar solvent molecules, increasing the affinity between substances and solvents, and promoting dissolution. However, due to the large non-polar indole ring and phenyl structure in the molecule, the overall solubility is limited, and the solubility in non-polar solvents (such as n-hexane, benzene) is poor. The force between the non-polar part and the non-polar solvent molecules is weak, and it is difficult to overcome the intermolecular force of the solute to disperse in the solvent.
On the melting point, the melting point of the substance is determined by experiments to be in a specific temperature range. There are hydrogen bonds, van der Waals forces and other interactions between molecules, and it is necessary to absorb enough energy to overcome these forces, so that the molecule can break away from the lattice binding and undergo a transition from solid to liquid. This specific temperature range is the melting point, which is an important basis for identification and purity judgment.
Density depends on the molecular weight and the degree of intermolecular packing. The molecular structure is complex, the mass is relatively large, and the intermolecular packing is closely packed through hydrogen bonds and other effects, resulting in its specific density value, which is of great significance in material separation, purification and preparation research.
In summary, the physical properties of 1 - {2- [ (2,6 -dihydroxyphenyl) oxy] -2 - (2,4 -dihydroxyphenyl) ethyl} -1H -indole, such as appearance, solubility, melting point and density, are determined by its unique molecular structure. These properties are crucial to the research and application of this substance in the fields of chemistry and pharmacy.
What are the synthesis methods of 1- {2- [ (2,6-dichlorobenzyl) oxy] 2- (2,4-dichlorophenyl) ethyl} -1H-imidazole?
The synthesis of 1 - {2- [ (2,6 -dihydroxyphenyl) oxy] -2 - (2,4 -dihydroxyphenyl) ethyl} -1H -indoles has attracted much attention in the field of organic synthetic chemistry. The synthesis process often requires delicate strategies and complicated steps.
To synthesize this compound, a feasible method is to use a suitable indole derivative as the starting material. The specific position of the indole is first modified, and a halogen atom, such as bromine or chlorine, can be introduced into the indole ring through a halogenation reaction for subsequent nucleophilic substitution reactions.
For the introduction of 2,6-dihydroxyphenyl and 2,4-dihydroxyphenyl groups, the reactivity of phenolic compounds can be exploited. The corresponding phenols are used as substrates and combined with modified indole derivatives through etherification. For example, under basic conditions, phenolic hydroxyl groups can undergo nucleophilic substitution reactions with halogenated hydrocarbons to construct [ (2,6-dihydroxyphenyl) oxy] and (2,4-dihydroxyphenyl) ethyl structures.
During the reaction process, the reaction conditions need to be carefully selected. Temperature control is critical, and different reaction steps may require different temperature ranges. Too low temperature may cause the reaction rate to be too slow, and too high may cause side reactions. At the same time, the choice of solvent cannot be ignored. Suitable solvents should be able to dissolve the reactants and have a positive impact on the selectivity and rate of the reaction.
In addition, the use of catalysts can effectively promote the reaction. For example, in nucleophilic substitution reactions, certain metal catalysts or organic base catalysts can enhance the activity of the reactants and improve the reaction efficiency.
During the synthesis process, the products of each step of the reaction need to be precisely separated and purified to ensure the smooth progress of subsequent reactions. Commonly used purification methods include column chromatography, recrystallization, etc., by which impurities such as unreacted raw materials and by-products can be removed.
What are the market prospects for 1- {2- [ (2,6-dichlorobenzyl) oxy] 2- (2,4-dichlorophenyl) ethyl} -1H-imidazole?
There are currently 1- {2- [ (2,6 -dioxobenzyl) oxy] -2- (2,4 -dioxophenyl) ethyl} -1H -indole, and its market prospects are as follows:
This compound has extraordinary potential in the field of medicinal chemistry. At the end of the observation of cancer treatment, the proliferation and invasion of many cancer cells are specific signaling pathways and protein expression. The compound has a unique structure and may be able to precisely target these key targets to inhibit the growth of cancer cells and induce their apoptosis. Looking at past studies, those with similar structures have shown good anti-cancer activity. It is expected that this product will have great potential in the development of new anti-cancer drugs, and it is expected to solve the suffering of patients and open a new chapter in medicine.
In the treatment of neurological diseases, it may act on mechanisms related to neurotransmitter metabolism and nerve cell protection. Today, neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease are raging, and the number of patients is increasing, but effective treatment methods are rare. After in-depth investigation, if this product can help repair nerve cell damage and relieve neuroinflammation, it will surely be able to provide a new path for the treatment of neurological diseases and save patients from fire and water.
Furthermore, in the field of materials science, due to the special electronic structure and physical properties of the compound, it may be applied to the field of organic optoelectronic materials. In today's era, organic Light Emitting Diode (OLED) and organic solar cells are developing rapidly, and there is an urgent need for new materials. This compound may optimize material properties, improve device efficiency and stability, and help the industry thrive. In the process of material innovation, add a strong pen.
However, although its market prospects are bright, there are also thorns ahead. The road of research and development is full of difficulties, and the synthesis process needs to be carefully optimized to improve yield and reduce costs. And the verification of safety and effectiveness requires rigorous clinical trials, long cycle and huge investment. Only by overcoming these difficulties can we shine in the market and achieve immortal feats for the well-being of humanity.